1.A Case of Left Ventricular Pseudo-false Aneurysm
Yuki Arakawa ; Eiji Murakami ; Kenichiro Azuma ; Kiyoshi Doi
Japanese Journal of Cardiovascular Surgery 2017;46(6):292-295
A 66-year-old man presented to a local doctor with a chief complaints of episodes of dizziness lasting several seconds. Electrocardiographic findings were suggestive of arrhythmia and old myocardial infarction, and the patient was therefore referred to our hospital. Left ventriculography showed an aneurysm at the posteroinferior wall of the left ventricle, while coronary angiography showed chronic total occlusion of the left circumflex branch (segment 13) and a coronary-pulmonary artery fistula with a coronary aneurysm. On computed tomography, the orifice of the ventricular aneurysm was small, measuring approximately 10 mm. Magnetic resonance imaging showed wall thinning and mural thrombus in the ventricular aneurysm, with aneurysmal dilatation during systole. Suspecting a ventricular false aneurysm resulting from old myocardial infarction, left ventricular reconstructive surgery and resection of the coronary artery aneurysm were performed. Intraoperatively, myocardial necrosis of the posteroinferior wall accompanied by the ventricular aneurysm was seen. There was no pericardial adhesion to the ventricular aneurysm, and the diameter of the orifice of the aneurysm was approximately 10 mm. The ventricular aneurysm was cut open and then closed using a direct suture combined with patch repair. As for the coronary artery aneurysm, the inflow and outflow arteries were each clipped before the wound was closed. The patient had a favorable postoperative course and was discharged from the hospital on the 15th day after surgery. The pathological examination showed residual cardiomyocytes within the aneurysmal wall, thereby establishing the diagnosis of a pseudo-false aneurysm. Our experience with this rare case is reported.
2.Hospital-based screening to detect patients with cadmium nephropathy in cadmium-polluted areas in Japan.
Toru SASAKI ; Hyogo HORIGUCHI ; Akira ARAKAWA ; Etsuko OGUMA ; Atsushi KOMATSUDA ; Kenichi SAWADA ; Katsuyuki MURATA ; Kazuhito YOKOYAMA ; Takehisa MATSUKAWA ; Momoko CHIBA ; Yuki OMORI ; Norihiro KAMIKOMAKI
Environmental Health and Preventive Medicine 2019;24(1):8-8
BACKGROUND:
In health examinations for local inhabitants in cadmium-polluted areas, only healthy people are investigated, suggesting that patients with severe cadmium nephropathy or itai-itai disease may be overlooked. Therefore, we performed hospital-based screening to detect patients with cadmium nephropathy in two core medical institutes in cadmium-polluted areas in Akita prefecture, Japan.
METHODS:
Subjects for this screening were selected from patients aged 60 years or older with elevated serum creatinine levels and no definite renal diseases. We enrolled 35 subjects from a hospital in Odate city and 22 from a clinic in Kosaka town. Urinary ß-microglobulin and blood and urinary cadmium levels were measured.
RESULTS:
The criteria for renal tubular dysfunction and the over-accumulation of cadmium were set as a urinary ß-microglobulin level higher than 10,000 μg/g cr. and a blood cadmium level higher than 6 μg/L or urinary cadmium level higher than 10 μg/g cr., respectively. Subjects who fulfilled both criteria were diagnosed with cadmium nephropathy. Six out of 57 patients (10.5% of all subjects) had cadmium nephropathy.
CONCLUSIONS:
This hospital-based screening is a very effective strategy for detecting patients with cadmium nephropathy in cadmium-polluted areas, playing a complementary role in health examinations for local inhabitants.
REGISTRATION NUMBER
No. 6, date of registration: 6 June, 2010 (Akita Rosai Hospital), and No. 1117, date of registration: 26 December, 2013 (Akita University).
Aged
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Aged, 80 and over
;
Cadmium
;
adverse effects
;
urine
;
Cadmium Poisoning
;
blood
;
complications
;
urine
;
Creatinine
;
urine
;
Environmental Exposure
;
adverse effects
;
Environmental Monitoring
;
Environmental Pollutants
;
adverse effects
;
urine
;
Female
;
Hospitals
;
Humans
;
Japan
;
Kidney Diseases
;
chemically induced
;
urine
;
Male
;
Middle Aged
;
Sex Distribution