1.Strategy for the effective management of adverse drug reactions
Yukari Deguchi ; Tomoki Inaba ; Yasuyo Fukuda ; Hitomi Yokota ; Yoko Kawaguchi
Japanese Journal of Drug Informatics 2010;12(1):30-35
Abstruct
Effective method for the management of information on adverse reactions is not uniformly in place, due to differences among medical facilities. We have been developing a strategy for the effective management of adverse drug reactions on the transition of clinical records from paper to electronic media.
We have taken a forward-thinking approach after 4 years identifying each year’s main target, predicted problems and how to address them in every year. The targets for the four 1-year periods were: enabling the collection and analysis of information on adverse reactions from paper-based clinical records, standardized handling of adverse reactions in situations where paper records are still in use, transition of adverse reaction information to electronic records, and sharing of information on adverse reactions where electronic records are in use. The Committee on Adverse Events conducted analysis of information on adverse reactions which were collected regardless of seriousness, disseminated useful information to all medical staff, and determined the degree to which each period target was achieved.
The transition to electronic form of information on adverse reactions achieved 0% success within the target period. Establishing effective management of adverse reactions will require 5 years, with as yet unresolved issues remaining. During 5 years, 767 incidents of adverse reactions were reported, 73.1% by physicians, the proportion by nurses increasing from 6.7% to 22.3%.
Strategic approach will help to establish a effective management of adverse reactions, which contribute to the adequate use of drugs and safety management of patients.
2.Evaluation of the effect of analgesics for cancer patients using their pain descriptions
Kikuyo Nishida ; Yukio Toyama ; Kumi Kuno ; Shigeki Hirano ; Yuko Deguchi ; Yuiko Matsuda ; Takashi Watanabe ; Chie Yamazeki ; Yukari Itakura ; Hiroko Saito ; Takaaki Hasegawa
Palliative Care Research 2009;4(1):207-213
Purpose: The present study aims to evaluate the effect of analgesics in cancer patients based on their pain descriptions. Methods: The relationship between the words that patients used to describe their pain due to cancer and the efficacy of treatment with analgesics such as non-steroidal anti-inflammatory drugs (NSAIDs) or opioids was evaluated. Results: We recorded 529words that were used by 164patients to describe their pain and pain quality and classified them into 108types of pain.For patients who used the actual word 'dull' or one with a similar meaning, treatment with opioids was effective. However, treatment with opioids was less effective in patients who used words such as "numb" and "tingling". Conclusion: We were able to gain a good understanding of cancer pain by listening to the actual words that patients used when complaining of pain. These findings suggested that we could choose a suitable medication through evaluation of the actual words cancer patients used to describe their pain and successfully relieve their pain. Palliat Care Res 2009: 4(1): 207-213