Cyclopia is a rare congenital fetal anomaly, characterized by a single median eye and a grotesquily shaped nose(proboscis) that arises from the supraorbital area. It is consistently associated with serere holoprosencephaly, which is the failure of cleavage of the prosencephalon with a deficite in the midiline facial development. Holoprosencepphaly occurs in as many as 1 to 2 % of diabetic mothers. A case of cyclopia delivered from a diabetic mother is presented with a brief review of literatures.
Holoprosencephaly ; Humans ; Mothers* ; Prosencephalon