1.10-11 Having Residents under the COVID-19 Pandemic - Experiences in the Spring of 2020
Kayoko MATSUSHIMA ; Eriko OZONO ; Yusuke MATSUZAKA ; Syoko ASHIZUKA ; Noriko SHIGETOMI ; Toshimasa SHIMIZU ; Masafumi HARAGUCHI ; Takeshi WATANABE ; Takashi MIYAMOTO ; Hayato TAKAYAMA ; Kenichi KANEKO ; Yuji KOIDE ; Atsuko NAGATANI ; Hisayuki HAMADA
Medical Education 2020;51(3):331-333
2.Effects of Histamine-2 Receptor Antagonists and Proton Pump Inhibitors on the Rate of Gastric Emptying: A Crossover Study Using a Continuous Real-Time 13C Breath Test (BreathID System).
Takashi NONAKA ; Takaomi KESSOKU ; Yuji OGAWA ; Kento IMAJYO ; Shogo YANAGISAWA ; Tadahiko SHIBA ; Takashi SAKAGUCHI ; Kazuhiro ATSUKAWA ; Hisao TAKAHASHI ; Yusuke SEKINO ; Eiji SAKAI ; Takashi UCHIYAMA ; Hiroshi IIDA ; Kunihiro HOSONO ; Hiroki ENDO ; Yasunari SAKAMOTO ; Koji FUJITA ; Masato YONEDA ; Tomoko KOIDE ; Hirokazu TAKAHASHI ; Chikako TOKORO ; Yasunobu ABE ; Eiji GOTOH ; Shin MAEDA ; Atsushi NAKAJIMA ; Masahiko INAMORI
Journal of Neurogastroenterology and Motility 2011;17(3):287-293
BACKGROUND/AIMS: The effects of Histamine-2 receptor antagonists and proton pump inhibitors on the gastrointestinal motility have not yet been sufficiently investigated. The aim of this study was to determine the effects of intravenous bolus administration of famotidine and omeprazole on the rate of gastric emptying using the continuous 13C breath test (BreathID system, Exalenz Bioscience Ltd, Israel). METHODS: Twelve healthy male volunteers participated in this randomized, 3-way crossover study. After fasting overnight, the subjects were randomly assigned to receive 20 mg of famotidine, 20 mg of omeprazole or 20 mL of saline alone by intravenous bolus injection before a test meal (200 kcal per 200 mL, containing 100 mg of 13C-acetate). Gastric emptying was monitored for 4 hours after the ingestion of test meal by the 13C-acetic acid breath test performed using the BreathID system. RESULTS: No significant differences in the calculated parameters, namely, the T1/2, Tlag, GEC, beta and kappa, were observed among the 3 test conditions. CONCLUSIONS: The study revealed that intravenous administration of gastric acid suppressant drugs had no significant influence on the rate of gastric emptying in comparison with that of saline alone as a placebo. Our results indicating the absence of any effect of either famotidine or omeprazole on accelerating the rate of gastric emptying suggest that both medications can be administered safely to patients suffering from hemorrhagic peptic ulcers who need to be kept nil by mouth from the viewpoint of possible acceleration of gastrointestinal motility in the clinical setting.
Acceleration
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Administration, Intravenous
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Breath Tests
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Cross-Over Studies
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Eating
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Famotidine
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Fasting
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Gastric Acid
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Gastric Emptying
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Gastrointestinal Motility
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Humans
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Male
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Meals
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Mouth
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Omeprazole
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Peptic Ulcer
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Proton Pump Inhibitors
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Proton Pumps
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Protons
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Stress, Psychological
3.Comparative Study of 2 Different Questionnaires in Japanese Patients: The Quality of Life and Utility Evaluation Survey Technology Questionnaire (QUEST) Versus the Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease Questionnaire (FSSG).
Takashi NONAKA ; Takaomi KESSOKU ; Yuji OGAWA ; Shogo YANAGISAWA ; Tadahiko SHIBA ; Takashi SAKAGUCHI ; Kazuhiro ATSUKAWA ; Hisao TAKAHASHI ; Yusuke SEKINO ; Hiroshi IIDA ; Hiroki ENDO ; Yasunari SAKAMOTO ; Tomoko KOIDE ; Hirokazu TAKAHASHI ; Masato YONEDA ; Shin MAEDA ; Atsushi NAKAJIMA ; Eiji GOTOH ; Masahiko INAMORI
Journal of Neurogastroenterology and Motility 2013;19(1):54-60
BACKGROUND/AIMS: The aim of this study was to examine the convenience of the quality of life and utility evaluation survey technology (QUEST) questionnaire and the frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) questionnaire as self-assessment diagnostic instrument. METHODS: This was a two-way crossover study conducted over 6 weeks from September 2010 to November 2010. The subjects were 60 consecutive patients admitted to the Hiratsuka city hospital with a gastrointestinal condition, regardless of the coexistence of heartburn. They were assigned to fill in both the QUEST and FSSG questionnaires in random order. We analyzed the time taken to complete the questionnaires, whether subjects asked any questions as they filled in the questionnaire, and the questionnaire scores. RESULTS: Comparison of the QUEST and the FSSG revealed significant differences in the completion time (196.5 vs. 97.5 seconds, respectively; P < 0.0001) and in whether subjects asked any questions (37 vs. 15 subjects, respectively; P < 0.0001). Completion time in QUEST scores of > or = 4 was lower than < 4 (170.5 vs. 214.0 seconds, respectively; P = 0.022), and the QUEST score was significantly higher without questions than with question (3 vs. 1 points, respectively; P = 0.025). CONCLUSIONS: This study revealed that the FSSG questionnaire may be easier for Japanese subjects to complete than the QUEST questionnaire.
Asian Continental Ancestry Group
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Cross-Over Studies
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Gastroesophageal Reflux
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Heartburn
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Hospitals, Urban
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Humans
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Quality of Life
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Surveys and Questionnaires
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Self-Assessment