1.Images of International Health and Nursing, in College Students in Fiji, Taiwan and Japan
Kiyoshi YOSHIMIZU ; Toyohiko KODAMA ; Sayaka OGURI ; Yuji FUJIMOTO ; Naruyo KANZAKI ; Setsuko UMEZAKI ; Bei Jia HE ; Koichi SHINCHI
Journal of International Health 2011;26(1):21-28
Images of the concepts of “International Health” and “International Nursing” may differ among countries. In this study, we examined the images of these concepts among 49 Fijian students, 85 Taiwanese students, and 377 Japanese students by self-administered questionnaire between 2007 and 2008. Full usable responses were received from 45 (91.8%) Fijian students, 69 (80.0%) Taiwanese students, and 352 (93.4%) Japanese students.
The results were as follows.
Ninety six percent of Japanese nursing students, 89% of Japanese medical students, 77% of Japanese student from four other faculties, 58% of Fijian students, and 26% of Taiwanese students reported their image of “International Health” to entail “Hygiene in developing countries”.
Ninety-two percent of Japanese nursing students, 92% of Japanese medical students, 40% of Fijian students, and 35% of Taiwanese students reported their image of “International Nursing” to entail “Nursing cooperation in developing countries”.
The images of “International Health” and “International Nursing” among the Fijian and Taiwanese students were of“Public health and nursing for foreigners living in Fiji or Taiwan”, and “Public health and nursing skills, and advanced medical systems in Westerns countries”. Most students in the three countries had a strong interest in-International Health and Nursing”.
Increasing chance of taking international information and knowledge of Japanese college students may influence the result of this study. Education and rearing students who will work in the field of international health was considered very important.
2.Prognostication of early-onset endometrioid endometrial cancer based on genome-wide DNA methylation profiles
Takuro HIRANO ; Eri ARAI ; Mao FUJIMOTO ; Yuji NAKAYAMA ; Ying TIAN ; Nanako ITO ; Takeshi MAKABE ; Wataru YAMAGAMI ; Nobuyuki SUSUMU ; Daisuke AOKI ; Yae KANAI
Journal of Gynecologic Oncology 2022;33(6):e74-
Objective:
The aim of this study was to establish criteria that would indicate whether fertility preservation therapy would likely be safe for patients aged 40 years or less with endometrioid endometrial cancer based on their DNA methylation profile.
Methods:
Forty-nine fresh-frozen tissue samples from patients with endometrial cancer from an initial cohort and 31 formalin-fixed paraffin-embedded tissue samples from a second cohort were subjected to genome-wide DNA methylation analysis using the Infinium MethylationEPIC BeadChip.
Results:
Epigenomic clustering of early-onset endometrial cancer was correlated with the widely used recurrence risk classification. Genes showing differences in DNA methylation levels between the low-recurrence-risk category and intermediate- and high-risk categories were accumulated in pathways related to fibroblast growth factor and nuclear factor-κB signaling. DNA hypomethylation and overexpression of ZBTB38 were frequently observed in the low-risk category. Eight hundred thirty-one marker CpG probes showed area under the curve values of >0.7 on the receiver operating characteristic curve for discrimination of patients belonging to the low-risk category. By combining marker CpG sites, seven panels for placing patients into the low-risk category with 91.3% or more sensitivity and specificity in both the initial and second cohorts were established.
Conclusions
DNA methylation diagnostics criteria using up to 6 of 8 CpG sites for LPP, FOXO1, RNF4, EXOC6B, CCPG1, RREB1 and ZBTB38 may be applicable to recurrence risk estimation for patients aged 40 years or less with endometrial cancer, regardless of tumor cell content, even if formalin-fixed paraffin-embedded biopsy or curettage materials are used.
3.Successful High-Dose Radiation Treatment for Chemo-Resistant Oral Squamous Cell Carcinoma in a Kindler’s Syndrome Patient
Yuka KIMURA ; Atsushi TANEMURA ; Yuma HANAOKA ; Eiji KIYOHARA ; Mari WATAYA-KANEDA ; Manabu FUJIMOTO ; Katsuto TAMAI ; Keisuke TAMARI ; Yuji SEO ; Kazuhiko OGAWA
Annals of Dermatology 2021;33(4):382-384
4.Successful High-Dose Radiation Treatment for Chemo-Resistant Oral Squamous Cell Carcinoma in a Kindler’s Syndrome Patient
Yuka KIMURA ; Atsushi TANEMURA ; Yuma HANAOKA ; Eiji KIYOHARA ; Mari WATAYA-KANEDA ; Manabu FUJIMOTO ; Katsuto TAMAI ; Keisuke TAMARI ; Yuji SEO ; Kazuhiko OGAWA
Annals of Dermatology 2021;33(4):382-384
5.Quantifying Bone Marrow Edema Adjacent to the Lumbar Vertebral Endplate on Magnetic Resonance Imaging: A Cross-Sectional Study of Patients with Degenerative Lumbar Disease
Toshio NAKAMAE ; Naosuke KAMEI ; Yoshinori FUJIMOTO ; Kiyotaka YAMADA ; Takayuki TAMURA ; Yuji TSUCHIKAWA ; Taiki MORISAKO ; Takahiro HARADA ; Toshiaki MARUYAMA ; Nobuo ADACHI
Asian Spine Journal 2022;16(2):254-260
Methods:
Patients with degenerative lumbar diseases, whose MRIs detected BME, were enrolled. On a T2-weighted fat-saturated MRI, BME appeared as a high-intensity region adjacent to the vertebral endplate. We calculated the contrast ratios (CRs) of BME and normal bone marrow using the signal intensities of BME, normal bone marrow, and the spinal cord. On computed tomography, we calculated Hounsfield unit (HU) values in the same area as BME, the sclerotic endplate, and normal bone marrow to assess bone density.
Results:
There were 16 men and 14 women, with an average age of 73.5 years. The mean CRs of BME and normal bone marrow were −0.015±0.056 and −0.407±0.023, respectively. BME’s CR was significantly higher than that of normal bone marrow (p<0.01). The HU values in the same area as BME, the sclerotic endplate, and normal bone marrow were 251.9±24.6, 828.3±35.6, and 98.1±9.3, respectively; these values were significantly different from each other (p<0.01).
Conclusions
The CR on MRI is a useful quantitative assessment tool for BME in patients with degenerative lumbar diseases.
6.An Interim Report on Result of Knee Pain Chart Accumulation
Toshikatsu KITADE ; Shoji SHINOHARA ; Masanori AKANUMA ; Fujio ITO ; Jun TANABE ; Masayoshi HYODO ; Akiya KATAOKA ; Kaji SHIBA ; Futami KOSAKA ; Yuji MIYAKE ; Toshifumi TARAHARA ; Zaigen OH ; Toshikazu TAKAGI ; Keiji YOSHIKAWA ; Takumi ITO ; Yasuzo KURONO ; Toru SATO ; Masaaki SHINOHARA ; Hiroshi SANADA ; Katsuhiko MATSUMOTO ; Hiromitsu TANIMURA ; Renpu FUJIMOTO ; Tetsusai YAMAMOTO ; Mitsuru NAKAMURA ; Takao SAKAI ; Tabasu MATSUMOTO ; Takaharu IKEUCHI
Journal of the Japan Society of Acupuncture and Moxibustion 1987;37(4):250-256
7.Rehabilitation after Forequarter Amputation for Left Scapula Chondrosarcoma:A Case Report
Yudai FUJIMOTO ; Takaaki TANAKA ; Toru WAKAMATSU ; Seiji IKEDA ; Yuji KATO ; Norifumi NAKA
The Japanese Journal of Rehabilitation Medicine 2020;57(4):364-369
Forequarter amputation is a rare procedure, performed mainly for patients with malignant bone and soft tissue tumors. The present case involved a 59-year-old man with left scapula chondrosarcoma. Rehabilitation began on the second day after amputation for a left shoulder chondrosarcoma. We performed early mobilization, wound management, mirror therapy for phantom pain, strength training for the remaining muscles, and activities of daily living (ADL)/instrumental ADL (IADL) training for only the remaining upper limb. In addition, we made a shoulder disarticulation prosthesis. Six months after the operation, the International Society of Limb Salvage-Musculoskeletal Tumor Society functional score was 36.7% for 6 items and 73.3% for 3 items, while the Disability of Arm, Shoulder and Hand score was 31.7. The patient-reported outcome had a low score because of the lack of an upper limb, including the scapula. However, when he was discharged from the hospital, he gained self-care independence with only the remaining upper limb and resumed fishing as a hobby. We suggest that rehabilitation after forequarter amputation requires careful intervention based on a deep evaluation of the patient's ADL/IADL, hobbies, and quality of life, in accordance with the patient's lifestyle.
8.Rehabilitation after Forequarter Amputation for Left Scapula Chondrosarcoma:A Case Report
Yudai FUJIMOTO ; Takaaki TANAKA ; Toru WAKAMATSU ; Seiji IKEDA ; Yuji KATO ; Norifumi NAKA
The Japanese Journal of Rehabilitation Medicine 2020;():19010-
Forequarter amputation is a rare procedure, performed mainly for patients with malignant bone and soft tissue tumors. The present case involved a 59-year-old man with left scapula chondrosarcoma. Rehabilitation began on the second day after amputation for a left shoulder chondrosarcoma. We performed early mobilization, wound management, mirror therapy for phantom pain, strength training for the remaining muscles, and activities of daily living (ADL)/instrumental ADL (IADL) training for only the remaining upper limb. In addition, we made a shoulder disarticulation prosthesis. Six months after the operation, the International Society of Limb Salvage-Musculoskeletal Tumor Society functional score was 36.7% for 6 items and 73.3% for 3 items, while the Disability of Arm, Shoulder and Hand score was 31.7. The patient-reported outcome had a low score because of the lack of an upper limb, including the scapula. However, when he was discharged from the hospital, he gained self-care independence with only the remaining upper limb and resumed fishing as a hobby. We suggest that rehabilitation after forequarter amputation requires careful intervention based on a deep evaluation of the patient's ADL/IADL, hobbies, and quality of life, in accordance with the patient's lifestyle.
9.Applicability of the Self-Evaluation Scale of nursing practices for improving sleep quality among patients with dementia taking sleeping pills to general nurses
Yuichi IWAMOTO ; Narumi FUJINO ; Takaomi FURUNO ; Yuji FUJIMOTO ; Yuki KAMADA
Journal of Rural Medicine 2024;19(2):92-104
Objective: Many patients with dementia experience sleep-related problems. However, there is a lack of clarity regarding nursing practices that can address these issues. Thus, we developed a self-assessment scale for nursing practices to improve sleep quality among patients with dementia taking sleep medication and confirmed its validity and reliability. This study aimed to test the validity and reliability of this scale for adaptability to general nurses and test its applicability.Participants and Methods: The survey included basic attributes and questionnaire items related to nursing practices to improve sleep quality in patients with dementia taking sleeping pills. Data from 477 participants with no missing values in the survey items were used in the analysis. The self-evaluation scale of nursing practices for improving sleep quality among patients with dementia taking sleeping pills was based on a three-factor model, and confirmatory factor analysis was performed using structural equation modeling.Results: Goodness-of-fit indices were satisfactory, supporting the construct validity of the scale. Cronbach’s α coefficients for the total score and the three factors of the self-evaluation scale of nursing practices for improving sleep quality among patients with dementia taking sleeping pills exceeded 0.7.Conclusion: The development of this scale can improve the quality of nursing practice for patients with dementia who take sleeping pills. Moreover, it can serve as evidence for general nurses to participate in drug treatment and can be considered as basic research for appropriate drug treatment in nursing practice.