Objective To compare clinical curative effects of two types of compression hollow screws in the treatment of femoral neck fractures. Methods A retrospective analysis was carried out on clinical records of 87 cases of femoral neck fracture from February 1996 to September 2004 treated with two types of compression hollow screws,that is,doubleheaded compression hollow screws(46 cases,Group A) and AO titanium compression hollow screws(41 cases,Group B).Results A follow-up was conducted for 3 months~8 years(mean,4.2 years).No statistically significant differences were observed between the two groups.The intraoperative blood loss was significantly less and the time to bone union was significantly shorter in the Group B than in the Group A(t=5.147,P=0.000;t=5.472,P=0.000).The surgical outcomes were classified as "excellent" in 34 cases,"good" in 8,"fair" in 1,and "poor" in 3 in the Group A,while "excellent" in 37 cases,"good" in 2,"fair" in 2,and "poor" in no cases in the Group B,without statistically significant differences between the two groups in the rate of "good" or "excellent" results(89.1% vs 95.1%,?~2=0.398,P=0.528).No femoral head necrosis or non-union was found in the Group B. Conclusions Both of two types of compression hollow screws have showed advantages of simplicity of performance,minimal invasion,short operative time,reliable fixation,and high success rate,being an ideal option for femoral neck fractures.

Objective To dieuss clinical manifestations of the organs damage out of lung caused by my-coplasma pneumonia(MP) infection in children. Methods Clinical date of 383 children with mycoplasma pneumonia infection were retrospectively reviewed. Results Among 383 cases, a total of 81 cases(21.25 %) were accompanied by organs damage out of lung. Conclusion The organs damage out of lung were observed in many system, the rate of organs damage out of respiratory tract is high in children. Mistake may occur easily in diagnosis if the symptoms out of lung appear first.

Objective:To evaluate the equity of the secondary performance allocation in target hospital.Methods:Through the comparison on the Gini coefficient calculation,the calculation method of Gini coefficient developed by Jianhua Zhang was applied to estimate the secondary allocation result of performance salary in the target hospital from 2014 to 2015.Results:From 2014 to 2015,the Gini coefficient remained at 0.22 or so,the overall allocation was average.Conclusion:Estimating the Gini coefficient was beneficial for the hospital managers control the structure and level of the second performance distribution and modulate the program of the sencond performance distribution in time,so that the distribution of performance salary would be accordant to the designed program and acts as the direction of motivation.

Objective To study the characteristics of the serum free light chain ( sFLC ) and cytokines levels and the effects of cyclophosphamide (CTX) on patients with primary Sj(0)gren's syndrome (pSS) complicated with amyloidosis.Methods Nine patients of pSS with amyloidosis who were admitted to Department of Rheumatology of the hospital from Jan 2005 to Mar 2011 were selected.The serum levels of sFLC and cytokines TNF-α,TGF-β1,IL-4 were measured before and 3,6,12 months after the treatment respectively.Meanwhile,Twelve patients with pSS without complications were selected as controls.Repeated measures analysis of variance was used for data analysis.Results The sFLC in serum of pSS patients with amyloidosis was λ type,the κ type was not found.The level of serum sFLC after 12 months treatment [(22±42) mg/L]was significantly lower than before treatment [(180±15) mg/L].The levels of TNF-α,TGF-β1,IL-4 after 12months treatment [(24.0±1A),(58±5),(38.8±3.2) ng/L,respectively] were significantly lower than before treatment [(31.1±L0),(65±5),(61.2±3.8) ng/L,respectively].Conclusion The levels of serum sFLC and eytokines are abnormally increased in patients of pSS with amyloidosis.After treatment,the levels of cytokines are decreased initially which indicates that these cytokines may play a key role in the pathogenesis of pSS.CTX therapy may lead to better efficacy and more favorable prognosis.

Objective To investigate the changes of calmodulin kinase Ⅱ (CaMK Ⅱ) and cAMP responsive element binding protein(CREB) expressing in primary cultured hippocampal neurons and its relationship with learning and memory deficit after 2000 μW/cm2 electromagnetic radiation.Methods Primary cultured hippocampal neurons in vitro were randomly divided into normal control group,sham-radiated group,and 1 h/d,2 h/d,3 h/dradiation groups.The neurons in the radiation groups were received microwave exposure of 2000 μW/cm2.The change of CaMK Ⅱ and CREB protein in hippocampal neurons of each group of rats were measured with western blot,and the expression of CaMK Ⅱ and CREB mRNA in hippocampus were determined by RT-PCR.Results Compared with control group((0.78 ± 0.07),(0.62 ± 0.12)),the expression of CaMK Ⅱ protein (1 h/d(0.59 ±0.05),2h/d(0.44 ±0.08),3h/d(0.18 ±0.04)) and its mRNA(1h/d(0.41 ±0.08),2h/d(0.34 ±0.04),3h/d(0.24 ±0.02)) was obviously decreased (P＜0.05).Compared with control group((0.69 ±0.10),(0.80 ±0.12)),the expression of CREB protein(1h/d(0.49 ±0.05),2h/d(0.4 ±0.04),3h/d(0.17 ±0.03))and its mRNA (1 h/d (0.68 ± 0.11),2h/d (0.53 ± 0.08),3h/d (0.30 ± 0.03)) was obviously decreased after radiation(P＜0.05).Conclusion Electromagnetic radiation of 2000 μW/cm2 exposure could weaken the learning and memory abilities of rats and the decreases in the expression of CaMK Ⅱ and CREB protein and their mRNA in hippocampus may be involved in the pathophysiological process of learning and memory deficit.

Arthritis, Juvenile ; therapy ; Child ; Humans ; Macrophage Activation Syndrome ; therapy ; Plasmapheresis

Objective To inquire into the relationship between infections of Toxoplasma gondii and apoptosis of spermatogenic cells. Methods Apoptotic spermatogenic cells of mice infected with Toxoplasma gondii were examined by Wright-Giemsa staining and terminal deoxynucleotidyl trans-Icrase (TdT) mediated deoxyuridine triphosphate (dUTP)-biotin nick-end labeling (TUNED techniques. Results Apoptosis rate of infective group of Toxoplasma was significantly higher than thai oi control group (F

OBJECTIVE To know the bacterial distribution in the blood of septicemia patients and the characteristics of drug resistance.METHODS To train the blood in BD BACTEC 9050 full-automatic blood training system and to analyze it in the FOUTUNE IMS bacterial identification and hypersusceptibility analysis system of Fuxing Company.RESULTS The Gram-negative bacilli were in superiority with 64.9% of the total isolated bacteria.Then were the Gram-positive cocci,and Staphylococcus were the main.The Enterococcus and fungi were with a certain proportion.The drugs to which had relatively low resistance for the Gram-positive bacilli and the Gram-positive cocci were the carbapenems,the enzyme inhibitors and vancomycin.CONCLUSIONS The Gram-negative bacilli get priority in the blood bacteria in patients with septicemia during the last two years,the enterococci and fungi have a certain proportion.And the pathogenic bacteria have higher resistance clinically to antibacterial drugs.

Objective To investigate the serum cystatin C (CysC) and urinary albumin excretion (mALB) joint detection in di‐agnosis of early diabetic nephropathy injury .Methods 120 cases of determination of CysC and microalbuminuria in type 2 diabetic patients and 40 healthy people and related clinical and biochemical parameters were measured ,and the various factors by correlation analysis ,the determination of differences in early renal damage in diabetes and healthy people .Results the early diabetic nephropa‐thy group ,diabetic nephropathy group serum cystatin C and urinary microalbumin is higher than the normal control group ,CysC and mALB level had significant difference ,the difference was statistically significant (P<0 .05) ,the mALB was positively correla‐ted with serum CysC levels (r=0 .662 ,P<0 .05) ,and no obvious correlation of serum Cr ,BUN levels and mALB .Conclusion trace albumin serum cystatin C and urine is reflecting early renal function injury sensitive and reliable index ,serum cystatin C com‐bined detection of urine micro albumin contributes to kidney disease early diagnosis ,treatment and prognosis judgement .

Objective To investigate the value of serum α1 acid glycoprotein(AAG) and Homocysteine(Hcy) in different stage of renal damage in type 2 diabetes(T2DM ) .Methods a total of 128 patients with T2DM were recruited from January 2013 to Octo‐ber 2013 ,According to 24 h urinary albumin excretion rate (UAER) were divided into the first group ,the second and third groups , and choose 80 healthy cases over the same period as the normal control group .Serum AAG ,Hcy ,creatinine (Cr) and blood urea ni‐trogen (BUN) were detected ,the test results were analyzed statistically .Results There were significant differences in type 2 diabe‐tes mellitus group ,early diabetic nephropathy group ,clinical diabetic nephropathy group of the serum AAG ,Hcy levels(P<0 .05) , there were positively correlated (r=0 .673 ,P<0 .05) between UAER and serum AAG levels ,and were positively correlated (r=0 .35 ,P<0 .05) between UAER and Hcy levels .Conclusion Combined detection of serum AAG ,Hcy have a significant for early diagnosis of diabetic nephropathy and assessing the degree of renal injury in diabetes .