1.Predictive value of serum lactate combined with PIRO score in prognosis of septic patients
Xiangqun ZHANG ; Bo LIU ; Aimin XU ; Yugeng LIU ; Hong ZENG
Chinese Journal of Emergency Medicine 2017;26(2):176-180
Objective To investigate the predictive value of serum lactate combined with PIRO (Predisposition,Infection,Response and Organ dysfunction) score in the development of multiple organs dysfunction syndrome (MODS) in septic patients and to study procalcitonin (PCT),in order to provide guidelines for clinical care.Methods From April 2015 to July 2016,a total of 752 sepsis patients were enrolled and divided into MODS group (n =488) and non-MODS group (n =264) according to the criteria of MODS.At 28 d after admission,these patients were divided into survival group (n =477) and death group (n =275).PCT and lactate levels in serum were measured,and PIRO score of these patients was calculated.Then the differences in levels of PCT and lactate in serum were compared among patients at different PIRO score categories.ROC was constructed to observe the clinical values of the biomarkers,PIRO score and lactate combined with PIRO score in predicting prognosis.Result PCT,lactate levels in serum and PIRO score were significantly higher in MODS group and death group,showing significant positive correlation.The areas under ROC curves (AUCs) of serum lactate combined with PIRO score for predicting MODS were 0.906,which was significantly higher than that of serum PCT (0.716),serum lactate (0.851) and PIRO score (0.840) alone (all P < 0.05).Serum PCT,serum lactate and PIRO score were the independent predictors of MODS.Conclusions Serum lactate in combination with PIRO score was a valuable indicator in predicting development of MODS in septic patients.
2.Survey on the distribution of common allergens responsible for cases with allergic rhinitis in Tianjin district.
Wenjie SHI ; Jinmei ZHANG ; Peng LIN ; Yugeng ZHANG ; Peiyong SUN ; Xiaofei WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2011;25(5):220-223
OBJECTIVE:
To investigate the distribution of common allergens responsible for cases with allergic rhinitis in Tianjin district.
METHOD:
A total of 676 cases who are diagnosed with allergic rhinitis in Tianjin district, underwent a skin prick tests with 23 kinds of inhaling allergens and 20 kinds of ingestive ones. The samples were stratified on four age group. Then, an analysis was made to determine the distributive characteristics of allergens responsible for difference groups.
RESULT:
Among the surveyed local 676 cases with allergic rhinitis, higher positive rates was all inhaling group of allergens.
CONCLUSION
It is concluded that the mostly responsible common allergens for attacks of allergic rhinitis among local cases in Tianjin district are mites, flowers pollen in inhaling group of allergens.
Adolescent
;
Adult
;
Aged
;
Aged, 80 and over
;
Allergens
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analysis
;
immunology
;
Animals
;
Child
;
Female
;
Humans
;
Male
;
Middle Aged
;
Mites
;
immunology
;
Pollen
;
immunology
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Rhinitis, Allergic, Perennial
;
diagnosis
;
immunology
;
Skin Tests
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Young Adult
3.Objective evaluation of nasal ventilation function in healthy adults in Tianjin area.
Xuejie FAN ; Peng LIN ; Peiyong SUN ; Wenjie SHI ; Jinmei ZHANG ; Xianfeng WEI ; Yugeng ZHANG ; Jing BI ; Yue MI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2010;24(14):628-635
OBJECTIVE:
To establish reference values of acoustic rhinometry, rhinomanometry and rhinospirometer in healthy adults in Tianjin area, analyze the effects of age,sex and side on the value, investigate the correlation of the measure values, offer the diagnosis date for test nasal ventilation function in Tianjin area.
METHOD:
Four hundred and sixty-six healthy adults in Tianjin area were tested. A1 acoustic rhinometry was used to measure the minimum cross-sectional area (MCA), distance of the minimal cross-sectional area to the nostril (DCAN) and the nasal volume from 0-5 cm, 2-5 cm (V5, V2-5); At 150 Pa, 75 Pa and broms, NR6 Rhinomanometry was used to measure unilateral nasal inspiratory resistance (IR)and expiratory resistance (ER), bilateral nasal inspiratory and expiratory resistance (TIR and TER), and differences of the bilateral nasal resistance can be calculated; NV1 Rhinospirometer was used to measure unilateral inspiratory capacity (IC) and expiration capacity (EC), and the nasal partitioning ratio (NPR) can be calculated. Practical measure the distance of nostril to ahead of the inferior turbinate and compare with DCAN. Make the correlational analysis on different index of three exam.
RESULT:
Reference values of acoustic rhinometry: MCA was (0.45 +/- 0. 16) cm2 for male, (0.44 +/- 0.16) cm2 for female; V2-5 was (3.52 +/- 1.38) cm3 for male, (3.36 +/- 1.22) cm3 for female, V5 was (5.10 +/- 1.47) cm3 for male, (4.86 +/- 1.12) cm3 for female; DCAN have two distance, (2.22 +/- 0.398, 0.53 +/- 0.625) cm was for male, (2.10 +/- 0.37, 0.67 +/- 0.15) cm was for female. No significant gender, side and age differences were shown in MCA, V5, V2-5. Significant gender differences were shown in DCAN but no side and age differences. Reference values of rhinomanometry: Significant gender but no side and age differences were shown in IR, ER, TIR, TER. Reference values of rhinospirometer: IC was (2.06 +/- 1.10) L/20 s for male, (1.37 +/- 0.34) L/20 s for female, EC was (2.15 +/- 1.23) L/20 s for male (1.39 +/- 0.58) L/20 s for female. NPRi was 0.11 [0.05, 0.23],NPRe was 0.11 [0.05, 0.19]. Significant gender but no side and age differences were shown in IC and EC. No gender and age differences were shown in NPRi and NPRe. There was significant correlation found between MCA and IR/ER/IC/EC, IR and IC, ER and EC, Rlr and NPRi/ NPRe.
CONCLUSION
Acoustic rhinometry,rhinomanometry and rhinospirometer can be useful reference values to evaluate nasal ventilation function, more value will be found if use the three together.
Adolescent
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Adult
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Aged
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China
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Female
;
Humans
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Male
;
Middle Aged
;
Nasal Cavity
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physiology
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Nasal Mucosa
;
physiology
;
Nose
;
physiology
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Reference Values
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Respiration
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Rhinomanometry
;
standards
;
Rhinometry, Acoustic
;
standards
;
Young Adult
4.Analysis of mite-allergic characteristics in patients with allergic rhinitis.
Xiaolin PENG ; Peiyong SUN ; Wenjie SHI ; Jinmei ZHANG ; Lisheng WANG ; Yugeng ZHANG ; Peng LIN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(17):932-934
OBJECTIVE:
To investigate the characteristics of allergic rhinitis sensitized with mite, providing the evidence for the treatment plan of allergic rhinitis in Tianjin area.
METHOD:
The medical records of skin prick test results on 2390 allergic rhinitis patients from March 2009 to February 2012 were retrospectively studied. The data of mite sensitivity in gender, age, season, and regional differences were analyzed.
RESULT:
There was no significant difference of the positive rate of Dermatophagoides pteronyssinus and Dermatophagoides farinae between male and female (P > 0. 05); The positive rate of dust mite decreased gradually with the growth of the age in the three groups of < 18,18-39,40-60 years old, but the positive rate of the patients over the age of 60 years old increased then. There were significant differences of positive rate to dust mite in different season (P < 0.05). The positive rate of Dermatophagoides pteronyssinus was the highest in the autumn (55.4%), and the lowest in winter (39.7%). The positive rate of Dermatophagoides farinae was the highest in winter (73.8%), and the lowest in spring (47.2%). There was no significant difference of the positive rate to dust mite between urban and suburb (P > 0.05).
CONCLUSION
There were some relationship of the positive rate of dust mite with age and season, but not gender and region among allergic rhinitis in tianjin.
Adolescent
;
Adult
;
Aged
;
Aged, 80 and over
;
Allergens
;
analysis
;
immunology
;
Animals
;
Child
;
Child, Preschool
;
China
;
epidemiology
;
Female
;
Humans
;
Male
;
Middle Aged
;
Pyroglyphidae
;
immunology
;
Retrospective Studies
;
Rhinitis, Allergic
;
Rhinitis, Allergic, Perennial
;
epidemiology
;
immunology
;
Young Adult
5. Epidemiological characteristics and its trends of other infectious diarrhea diseases in infants in Inner Mongolia Autonomous Region, 2005-2016
Xiaofeng JIANG ; Huixia HAO ; Yugeng ZHANG ; Jian SONG ; Xia LEI ; Wenrui WANG
Chinese Journal of Infectious Diseases 2019;37(11):667-671
Objective:
To analyze the epidemiological characteristics and its trends of other infectious diarrhea diseases in infants in Inner Mongolia Autonomous Region.
Methods:
Statistical analysis was conducted on other infectious diarrhea cases of infants in Inner Mongolia Autonomous Region from China Information System for Disease Prevention and Control from 2005 to 2016. The main methods were descriptive epidemiology for population, area and time distribution of these registered cases in Inner Mongolia Autonomous Region. The trends were analyzed by the ratio of fixed base and ring base. Area map method was used for regional differences.
Results:
From 2005 to 2016, 17 760 other infectious diarrhea diseases of infants were reported in Inner Mongolia Autonomous Region, accounting for 58% of the total reported cases. The cases number and incidence showed an overall upward trend. After 2011, the growth rate of case reports and incidences slowed down relatively. The peak of the incidence was in July and August (4 739 cases), accounting for 27% of cases of the whole year. Seventy-three point forty-four percent of the cases were located in Hulunbeier City (5 161 cases, 29.06%), Hohhot City (4 465 cases, 25.14%) and Baotou City (3 417 cases, 19.24%) . Except for Wuhai City, the remaining 11 cities showed increased incidence of other infectious diarrhea diseases in infants. The ratio of male to female was 1.55∶1, and the incidence in males was higher than that in females every year. Twelve-month-old (5 800 cases, 33%) had the greatest proportion. Clinical diagnosis (56.26%) and confirmed diagnosis (43.51%) were the main categories, but the rate of pathogen labeling was only 7.60%.
Conclusions
After 2011, the incidence of other infectious diarrhea diseases of infants in Inner Mongolia Autonomous Region have slowed down relatively. However, the incidence has significant time, region and population aggregation.