The paper expounds the practical significance of the humanistic quality of medical staff,and probes into the cultivation path according to the problems existing in the humanistic quality of medical staff,aimed at promoting the new health care reform orientation,in order to better practice the modern biological-psychological-social medical model,and to provide a useful reference for constructing harmonious doctor-patient relationship.

From the perspective of government health budget management system, health budget decision-making and health budget reform, to make a systematic introduction of government health budget reform’s characteristics, measurement and related experiences in some countries, especially Organization for Economic Cooperation and Development(OECD) countries, so as to provide references for the improvement of government health budget management in China.

s Medicine is a kind of culture. The ideal settlement of practical medical problems must be built on medical cultural platform. The higher demand of modern medical practice to the talents is to cultivate their medical cultural quality. The medical cultural quality and its education is regular. Therefore, only by integrating medical humanistic education into medical cultural education can the medical humanistic education come into being and be enforced.

Objective To correlate the expression levels of interferon inducible genes (IFIGs) with disease activity and clinical features in systemic lupus erythematosus (SLE) patiems,.Methods Peripheral blood cells obtained from 67 SLE patients and 23 healthy donors (HDs) were subjected to real-time PCR to measure the transcriptional levels of five IFIGs (OAS-1,Mx-1,Ly6e,IFIT1 and IFIT4).Interferon scores were calculated and were compared between various groups of SLE patients as well as between patients and controls;ISRE lucife:rase reporter gene activity was measured in 17 of 67 patients and correlated with interferon score.Results Interferon scores were strongly correlated with ISRIE reporter gene aetivity,which represented for the type Ⅰ interferon activity in serum.The expression.levels of IFIGs and jinterferon scores were significantly elevated in SLE patients compared with HDs (P＜0.0001).Interferon scores were correlated positively with SLEDAI-2K(P=0.0006) and negatively with C3 levels(P=0.0162).Interferon scores were also significantly elevated in SLE patients with a positive anti-Sm or anti-RNP autoantibodies.Clonclusion The interferon score may be regarded as a good indicator for serum type I interferon activity in SLE and serves as a new hiomarker for disease activity in SLE patients.

Objectives:To study efficiency characteristics and changes of county hospitals based on data envel-opment analysis model from 2008 to 2012 . Methods:A three-stage DEA model which can exclude the external envi-ronment variable on its efficiency is also added along with the C2 R and BC2-DEA traditional model. Results: From 2008 to 2012, the technical efficiency value was ranging between 0. 723 and 0. 681 in county hospitals, the pure technical efficiency was 0 . 785~0 . 771 and the scale efficiency value scaled between 0 . 908 and 0 . 897 . These values showed a low efficiency, but had annually improved. This reflects that the new health care reform policies have played an important role in improving county hospitals efficiency. Development of medical service ability is behind the development of hospital scale. How to improve the service and management capabilities has gradually become a major direction to improve the county hospital efficiency.

Objective:Based on the perspective of supply and demand balance, to analyze the implementation effects of primary-feature medical services measures in medical alliances.Methods:From July to September 2019, two regions with different levels of economic development were chosen, and from each region one leading hospital and two community health service centers/township hospitals were selected from its medical alliance. A total of 213 medical staff and 703 residents were surveyed, to learn their awareness and performance appraisal of these feature services.Frequency and proportion were calculated in a descriptive statistical analysis. The scores of the performance appraisal of both supply and demand sides were tested by independent sample t. Results:In the performance appraisal of such measures, the average scoring by medical staff was 4.39±0.07, and that by residents was 3.85±0.06; the residents were more concerned with service capabilities and contents, while medical staff were more concerned with service content and delivery mode; supply and demand sides were found with consensus in terms of improving the medical service quality of chronic diseases in primary level and service accessibility.Conclusions:The county-level medical alliances should focus on enhancing their capacity of primary medical services, and improving their primary service mode with the help of medical insurance institutions. Meanwhile, it is imperative to optimize the primary medical service policy in view of supply and demand balance.

Building an integrated health care service system is key to the Healthy China strategy. Based on the integrated health care service conceptual framework, the authors took two pilots regions of health-centered medical alliances in Zhejiang province as an example, and analyzed their conception framework, organizational structure, operation elements and effects. The study found initial success of the two alliances in terms of the contents, capabilities, effects and satisfaction of primary health care service. Such alliances feature a health-centered multi-entity participation mechanism, carry out health care and prevention integration leveraging the information platform, hence conducive to the effective governance of the alliances. However, the contents of their health related services are expected to be broadened and deepened; functionalities of health-related institutions need to be clarified and refined, while their performance appraisal needs to be further improved.

Objective To investigate the the association between psychological behavior and self-awareness of obese children and family factors,in order to provide scientific basis for clinical intervention in obese children. Methods Fifty children with obesity ( obesity group) and fifty healthy children ( control group) were included in the study. All children were evaluated with the Achenbach Child Behavior Checklist (CBCL),Piers-Harris Child's self-concept Scale ( PHCSS), Family Environment Scale-Chinese Version ( FES-CV) and Egma Minnen av Bardndosnauppforstran(EMBU). Moreover,correlation analysis was applied in the study to explore family factors affecting behavioral problems and self-awareness of obese children. Re-sults Compared with control group,significant higher ratio of abnormal behaviors was found in children with obesity (P<0. 05). FES-CV showed that the degree of expressiveness((3. 16±1. 93),(4. 65±1. 02)),intel-lectual-cultural orientation((5. 31±1. 28),(6. 10±1. 83)) and active-recreational((2. 78±1. 36),(4. 84± 1. 72)) were lower than control group,and the degree of family conflict((4. 11±1. 45),(3. 32±1. 27)) and control((6. 42±1. 37),(5. 09±1. 65)) were higher in children with obesity (P<0. 05). Moreover,EMBU showed that emotional warmth score was significantly lower in obese group than that in control group (P<0. 01),and the scores of parent's rejection,father's severity,parent's over-interference,and mother's over-protection were significantly higher than the scores in control group(P<0. 05). In obese group,the correlation analyses showed a negative association between social withdrawal in children's behavioral problems and fami-ly expressiveness (r=-0. 62,P<0. 01),and a positive association between aggressivity and family conflict (r=0. 39,P<0. 05). There was a positive correlation between internalizing behavioral problems and mother's over-protection and over-interference(r=0. 60,P<0. 01). Low self-awareness was positive associated with parent's rejection and father's severity(r=0. 46,0. 51,0. 44 respectively,P<0. 05). Conclusion A signifi-cant higher risk of abnormal psychological behaviors and low self-concept can be found in children with obe-sity,which can closely related to family factors.

Objective:To observe the expression of molecular chaperone-mediated autophagy in hippocampal neurons and its relationship with brain injury after recurrent-status seizures.Methods:Seven-day-old SD rats were divided into two groups according to simple randomization: the control group (NS group, 6 rats) and the recurrent-seizure group (RS group, 39 rats). Rats in the RS group were subjected to recurrent seizures after repeated inhalation of flurothyl, with 30 minutes once each day for consecutive 7 days.A total of 30 convulsive models were successfully established (9 rats that failed to establish models were discarded), and they were further divided into 0 h, 1.5 h, 3 h, 12 h and 24 h after the last seizure according to simple randomization, with 6 rats in each group.Western blot and reverse transcription-polymerase chain reaction (RT-PCR) were adopted for the observation of the expression of molecular chaperone-mediated autophagy markers [heat shock cognate protein 70 (Hsc70), lysosome-associated membrane protein type 2a (LAMP-2a), heat shock protein 40(HSP40) and heat shock protein 90(HSP90)] in hip-pocampal neurons, and apoptosis was detected by TdT-mediated dUTP nick-end labeling (TUNEL).Results:(1) RT-PCR and Western blot showed that, compared with the NS group, the expression of Hsc70, as a molecular chape-rone, started to increase at 1.5 h and continued until 24 h after the last seizure in the RS group ( P<0.05). HSP90 increased immediately after the last seizure and lasted until 24 h after the seizure ( P<0.01); the expression of HSP40 and LAMP-2a also showed high expression after the last seizure episode ( P<0.05). (2) The TUNEL method showed that the number of apoptotic cells in the hippocampal CA1 region increased significantly at 3 h (36.33±5.16)/40 field, 12 h (44.83±4.83)/40 field and 24 h (54.83±7.16)/40 field after the last seizure compared with NS group(15.16±2.48)/40 field ( P<0.01). (3) Pearson correlation analysis showed that the level of apoptosis in hippocampal CA1 region of rats after recurrent seizures was positively correlated with the expression of molecular chaperone marker molecules (Hsc70: r=0.734, P=0.001; LAMP2a: r=0.790, P<0.001). Conclusions:After recurrent seizures in developmental rats, the presence of increased expression of multiple molecular chaperone-mediated autophagy, which may positively correlate with apoptosis, may be involved in the process of brain injury.

At present,some medical personnel have problems in professional resilience,such as post competence,psychological resilience,self-efficacy and decreased professional identity.In order to strengthen the training of medical personnel professional resilience,starting with the mechanisms of professional resilience training,management guaran-tee,hospital culture construction and self-construction,it puts forward that the government and society should build the training system of multiple subjects,improve the occupational safety and welfare guarantee,and optimize the psy-chological environment of medical personnel;medical institutions should create a good hospital culture atmosphere,strengthen the material support of occupational resilience training,and establish the vocational resilience training pro-gram;medical personnel should enhance their professional quality,enhance professional identity,and establish a harmo-nious interpersonal relationship.