1.The influence to present depth doses and peripheral doses by enhanced dynamic wedge and physical wedge
Yueqin YANG ; Yinghai CHEN ; Ruoyu WANG
Chinese Journal of Medical Physics 2001;18(1):12-13
Purpose: To understand the influence to depth doses and peripheral doses by Enhanced Dynamic Wedge and physical wedge.Methods: The depth doses and peripheral doses were measurement for open field and Enhanced Dynamic Wedge field as well as physical wedge.Results: ⑴ depth doses and peripheral doses for Enhanced Dynamic Wedge fields was very similar to those for open fields ⑵ depth doses and peripheral doses for physical wedge fields was large than those for open fields. Conclusion: depth doses measured for open fields can also be used for Enhanced Dynamic Wedge fields dose calculation. Wedge depth dose must be used in the physical wedge fields dose calculation. It should be pay attend to peripheral doses for physical wedge fields in the clinic.
2.Changes of IL-8 and ICAM-1 in early stage of cerebral white matter damage and their correlations with prognosis in premature infants
Yang DUAN ; Fuqiang SUN ; Yueqin LI
Journal of Clinical Pediatrics 2014;(9):821-824
Objective To explore the IL-8 and ICAM-1 in premature infants with cerebral white matter damage (CWMD) and their correlations with prognosis. Methods One hundred and two cases of CWMD were selected from March 2009 to June 2012 as experimental group and 42 cases of normal preterm children were selected as control group. Serum IL-8 and ICAM-1 levels were measured during 48-72 h after birth. Motor development index (psychomotor developmental index, PDI) and mental development index (mental development index, MDI) were evaluated by Bayley scale. The correlations of IL-8 and ICAM-1 levels with prognosis were analyzed. Results Serum IL-8 and ICAM-1 levels in the experimental group were signiifcantly higher than those in the control group (P<0.05). MDI and PDI scores in the experimental group were signiifcantly lower than those in the control group (P<0.05). There were negative correlations of serum IL-8 and ICAM-1 levels with MDI (r=-0.64, P<0.05;r=-0.66, P<0.05)+and PDI (r=-0.70, P<0.05;r=-0.71, P<0.05). Conclusions Serum IL-8 and ICAM-1 levels in infants with CWMD are signiifcantly increased, and are negatively correlated with MDI and PDI scores.
3.Analysis of influence of anesthetic effect, maternal and infant outcomes and safety of subarachnoid block using sulfentanyl combined with ropivacaine for patients with gestational hypertension in the cesarean section
Shuxiong ZHA ; Yueqin YANG ; Chao JIANG
Chinese Journal of Primary Medicine and Pharmacy 2017;24(9):1356-1361
Objective To study the influence of anesthetic effect,maternal and infant outcomes and safety of subarachnoid block used sulfentanyl combined with ropivacaine for patients with gestational hypertension in the cesarean section.Methods 180 cases of gestational hypertension ready to cesarean section were selected as study subjects,and they were randomly divided into A group,B group and C group by digital table method,60 cases in each group.A group used 10mg ropivacaine,B group used 13mg ropivacaine,C group used 5μg sulfentanyl combined with 10mg ropivacaine.The anesthetic effect,circulation function,duration of pain,operation time,neonatal Apgar score at 1 and 5 min after birth,neonatal weight,motor block evaluation after operation,adverse reaction and complication were compared in three groups.Results The anesthetic effect between B group and C group had no statistical difference (x2 =1.233,1.465,all P > 0.05).The anesthetic effect of B group and C group was better than that of A group(F =5.633,7.299,all P <0.05).The HR and MAP of every time points between A group and C group had no statisticaldifferences (F =1.313,1.265,all P > 0.05).Compared with T0,the HR and MAP of B group at T1,T2,T3,T4 had statistical differences compared with A group and C group(F =5.633,7.299,all P <0.05).The operation time of the three groups had no statistical difference(F =0.933,P > 0.05).The duration of pain between B group and C group had no statistical difference(t =0.822,P > 0.05).The duration of pain of A group was longer than that of B group and C group(F =8.316,P <0.05).The neonatal Apgar scores at 1 and 5 min after birth and neonatal weight of the three group had no statistical differences(F =0.822,0.929,all P > 0.05).The improved Bromage score between A group and C group had no statistical difference (t =2.627,1.991,all P > 0.05).The improved Bromage score between B group and A,C group had statistical differences(F =6.371,5.693,all P < 0.05).The complete recovery time of motor nerve of B group was much longer than that of A group and C group (F =8.924,P < 0.05).The incidence rates of vomit and nausea of A group and B group were much higher than that of C group(F =3.561,12.581,all P < 0.05).The incidence rate of bradycardia and hypotension of B group was much higher than that of A group and C group (F =8.273,10.833,all P < 0.05).Conclusion During subarachnoid block anaethesia using 5 μg sulfentanyl combined with l0mg ropivacaine can be applied to mild and moderate gestational hypertension,it has advantages such as less adverse reaction,good analgesic effect,less hemodynamic effect,and it is worthy of clinical promotion.
4.Effect of team-based tutorial system to nursing student in the order cultivation pattern
Yueqin CHEN ; Shuxia LIU ; Jinxu YANG
Chinese Journal of Practical Nursing 2016;32(7):545-548
Objective To explore the effect of team-based tutorial system to nursing student in the order cultivation Pattern.Methods This study used the convenience sampling method.109 students were choosed from orientation training classes that 2012 and 2013 grade as the research subjects.The 59 students from 2013 grade as the test group,implement team-based tutorial system to them in the fourth semester.The 50 students from 2012 grade that had been implemented general management as the control group,then compare the fourth semester final grade,classes atmosphere,the evaluation of patients and clinical teachers over the same period.Results The test group and control group students' scores of their fourth semester final grade,classes atmosphere,the evaluation of clinical teachers and patients were (92.39±2.39),(3.45±0.64),(95.33±2.01),(94.75±2.38) points and (90.91±2.62),(3.14±0.63),(91.00±1.82),(90.63±2.34) points.There was difference between them,and the difference was statistically significant (t=-7.82 ~ 3.06,P < 0.05).Conclusions The implementation of team-based tutorial system to nursing student in the order cultivation pattern can improve students' academic performance,improve their class atmosphere and their communication skills so that patients get good evaluation of patients and clinical teachers.
5.The effect of different dosages of low molecular weight heparin on acute pulmonary embolism and inhibition of pulmonary intimal hyperplasiain immature rats
Fuqiang SUN ; Yang DUAN ; Shengshun QUE ; Yueqin LI ; Suyan YANG
Journal of Clinical Pediatrics 2016;34(8):628-633
Objectives To investigate the effect of different dosages of low molecular weight heparin on acute pulmonary embolism and inhibition of pulmonary intimal hyperplasia in immature rats. Methods 90 male immature SD rats were randomly divided into ifve groups: sham group, pulmonary embolism group, low-low molecular heparin group (L-LMH), medium-low molecular heparin group (M-LMH) and high-low molecular heparin group (H-LMH). The model of acute pulmonary embolism was established through jugular vein injection with gel-foam solution. The rates in the L-LMH, M-LMH, H-LMH groups were treated with low molecular weight heparin by subcutaneous injection after surgery with a dosage of 0 . 005 ml/kg, 0 . 01 ml/kg, 0 . 02 ml/kg, twice a day. Animals in the control group were given saline injection. Arterial blood gas, pulmonary artery pressure (mPAP), right ventricular pressure (RVP), wall area/tube area, wall thickness/tube diameter, and the expression of PDGF-B and MCP-1 at gene and protein levels in lung tissue were detected on the 7 th ( 7 d), 14 th ( 14 d) and 28 th ( 28 d) after opration. Results There were signiifcant differences of PaO 2 among 5 groups on 7 d, 14 d and 28 d. PaO 2 in group M-LMH ( 105 . 1 ± 4 . 6 mm Hg) were signiifcantly higher than that of embolization group, L-LMH, but not H-LMH group at 28 d. mPAP of M-LMH group was lower than that in the other three intervention groups, but showed no signiifcant difference compared with sham group (P?>0 . 05 ). There were signiifcant differences of RVP on 7 d and 14 d. PDGF-B, MCP-1 of M-LMH group were signiifcantly lower compared with the other three intervention groups (P?0 . 05 ), but showed no signiifcant difference compared with sham group (P?>0 . 05 ). Wall area/tube area, wall thickness/tube diameter scores of M-LMH group had no signiifcance differences compared with sham group on 28 d (P?>?0 . 05 ). Conclusion Medium dose of low molecular weight heparin could ameliorate the acute pulmonary embolism and inhibit the proliferation of pulmonary arteries in rats.
6.Therapeutic efficacy of compound tea polyphenols gargle in he treatment of gingivitis in children
Yueqin XUE ; Lan YANG ; Mingpei LIU ; Al ET
Journal of Practical Stomatology 2001;0(03):-
Objective: To evaluate the therapeutic efficacy of compound tea polyphenols gargle in gingivitis treatment in children. Methods: A study of therapeutic efficacy was carried out in 240 patients(6~16 years) with gingivitis at random. Compound tea polyphenols gargle was appiled to 120 patients of the experimental group, chlorhexidine acetate solution to 60 patients in control group I, and tea polyphenols solution to 60 patients in the control group Ⅱ. The agents were used as mouthwashes for 6 days and 3 times daily. Results: The effective rate(%) in the experimental group, control group Ⅰ and control group Ⅱ were 98.33, 95.00 and 73.33 respectively. Compound tea polyphenols gargle was as effective as chlorhexidine against bacteria. Conclusion: Compound tea polyphenols gargle is effective in the treatment of children's gingivitis.
7.Study on the output factors of asymmetrical rectangular electron beam field
Yinghai CHEN ; Yueqin YANG ; Yuhong MA ; Jin ZHENG ; Lijuan ZOU
Chinese Journal of Radiation Oncology 2009;18(5):413-415
nges in standard square field.
8.The measurement and analysis of output factor of lead block fields for high energy electron beam of Varian 2300 C/D linear accelerator
Yinghai CHEN ; Yueqin YANG ; Tao DENG ; Ruoyu WANG
Chinese Journal of Medical Physics 2001;18(1):14-15,28
Purpose: To analyses the variation regularity of output factor of lead block fields for high energy electron beam of Varian 2300 C/D linear accelerator. Methods: Output factors of lead block fields were measured for four standard applicators under various electron beam energy. Results: The variations of output factor with field side or with applicators size were no obvious regularity Output factor of lead block fields was related to standard applicators size and lead block fields side Output factor of lead block fields was related to electron beam energy. Conclusion: Electron beam energy, standard applicator size and lead block fields side had a obvious influence upon output factor. The accurate measurement should be performed for use electron beam energy in the clinic.
9.The effects of topiramate on the epileptiform discharge and related neurotrans mitters in hippocampus in seizure rats induced by penicillin
Rong YANG ; Mingzheng WANG ; Yinxia CHENG ; Yueqin LIANG
Chinese Pharmacological Bulletin 1987;0(01):-
Aim To investigate the effects of topiramate (TPM) o n the model of seizure rats induced by penicillin and explore its mechanism of ant iconvulsant action.Methods Using the model of seizure rats indu ced by penicillin localized injected in cortex, we investigated the effect of TP M on the changes of seizure extent and recorded the latency of epileptiform disc harge, frequency of epileptiform wave, highest wave of hippocampus EEG. The leve ls of Glu, Asp, Gly and GABA in hippocampus were determined by high performance liquid chromatography (HPLC). Results Compared with the model g roup, TPM (110 mg?kg -1, 440 mg?kg -1, ig) could significantly light ened the extent of seizure, prolonged the latency of epileptiform discharge, red uced the frequency of epileptiform wave and minished the highest wave of hippoca mpus EEG (P
10.Experimental study on the accuracy of output factor calculation for rectangular inserts of electron beams
Yinghai CHEN ; Yueqin YANG ; Tao DENG ; Chengquan CHANG
Chinese Journal of Radiation Oncology 1992;0(04):-
Objective To compare the accuracy of output factor calculation for rectangular inserts of electron beams by using three kinds of algorisms: square root, one dimensional formula and area periphery ration. Methods The differences between the values of output factor calculated by these three algorithms mentioned above and the results measured by ionization chamber for seven rectangular inserts were compared. Results When beam energy was fixed, the difference between calculated and measured output factors was larger for area periphery ration algorithm than that of the square root or one dimensional formula algorithms. The electron cone size, beam energy and rectangular inserts size all had some effect on the value of output factor calculated by the three algorithms. Conclusions The area periphery ration algorithm is not recommended for clinical use because of its great deviation. One dimensional formula and square root algorisms possess a good accuracy. One dimensional formula is superior to square root algorithm, but square root algorithm is more practical for clinical use.