Objective To establish the quality standard for Tibetan medicine MNXT granule.Methods Inula racemosa,Tinospora sinensis were identified by TLC; Isoalantolactone and alantolactone were determined by HPLC.Results Inula racemosa,Tinospora sinensis could be identified by TLC.The concentration of isoalantolactone was linear in the range of 0.281～0.842 μg,r=0.9998,with the average recovery rate being 98.5％,RSD being1.14％.The concentration of alantolactone was linear in the range of 0.232～0.696 μg,r=0.9999,with the average recovery rate being 97.4％,RSD being 1.10％.Conclusion The method was simple,accurate,repeatable and able to control the quality of preparation effectively.

Objective To analyze the use of outcome indicators and evaluation tools in randomized controlled trial(RCT)of music interventions for lung cancer-related anxiety and depression.Methods Nine databases were searched,and the literature was screened according to inclusion and exclusion criteria,followed by a summary of outcome indicators,and statistical analysis of classification and frequency of use according to the attributes of the outcome indicators.Results A total of 243 articles were retrieved,and 18 RCTs were finally included.The outcome indicators were classified into 8 indicator categories according to their functional attributes:anxiety scale(24.19%),depression scale(16.13%),quality of life scale(14.52%),sleep quality scale(9.68%),pain scale(4.84%),blood biochemical indicators(14.52%),vital signs(11.29%),and pulmonary and exercise function indicators(FEV1%,6MWD,BODE index)(4.84%).The problems are as follows:First,the overall risk of bias is high in the included RCTs.Second,the timing of measurement is variable due to inconsistency in the length of treatment.Third,the forms of music intervention are diverse.Besides,the use of other rating scales and objective indicators is low and safety indicators were neglected.Finally,the method of evaluation tools was single and some RCTs did not specify grading criteria.Conclusion The use of outcome indicators and evaluation tools in music interventions for lung cancer-related anxiety and depression has certain shortcomings,which affects the credibility of the trials.It is recommended to standardize the use of outcome indicators and establish a core set of indicators for clinical studies of music intervention for lung cancer-related anxiety and depression.

"State-target medicine" is a traditional Chinese medicine （TCM） diagnosis and treatment theoretical system proposed by Academician Tong Xiaolin based on the current development of modern medicine. The active stage of gastric ulcer， as a precancerous state of gastric cancer， has a great impact on people's health. Prof. ZHOU Xuewen， a master of TCM， innovatively put forward the theory of "toxicity-heat" etiology for the active stage of gastric ulcer， which plays an important guiding role in clinical diagnosis and treatment. The article took the theoretical system of "state-target medicine" as the framework to explain the rationale， method， formula， and medicine of Prof. ZHOU Xuewen， who applied the Xiaoyong Kuidekang based on the "toxicity-heat" theory to treat the gastric ulcer in the active stage. The Chinese medical name of gastric ulcer， "gastric carbuncle"， was established， and it was believed that gastric ulcer is born due to "toxicity" and is based on "toxicity and heat". In the course of the disease， "toxicity"， "heat"， "deficiency"， and "stasis" coexisted， and its pathogenesis was divided into three phases， namely， toxicity-heat accumulation phase， toxicity-heat affecting the health phase， and weakened body resistance and strengthened toxicity phase. According to the positioning of gastric ulcer as an "internal carbuncle"， Prof. ZHOU Xuewen proposed the treatment of gastric ulcer in the active stage with "carbuncle theory" and introduced the surgical methods of "elimination"， "support"， and "tonifying" into the treatment of gastric ulcer in the active stage. Prof. ZHOU Xuewen took "clearing heat and removing toxins， eliminating carbuncle and generating muscle" as the basic treatment of the disease. For different stages of the disease， Prof. ZHOU Xuewen emphasized the use of the methods of clearing heat and removing toxins， supporting rot and muscle growth， and strengthening the spleen and harmonizing the stomach and created the representative formula for the treatment of gastric ulcer in the active stage with "carbuncle theory"， namely "Xiaoyong Kuidekang"， which could regulate state and targets.