This paper introduced and analyzed the unique geographical location and diverse climatic conditions in the yunnan region, its rich reservation of regional medical plant resources, and the local history, doctors, literatures and medical schools of Traditional Chinese Medicine (TCM). Besides, we combined the characteristics with the current national development strategy "The Belt and Road Initiative" , "cultural soft power" and the Yunnan’s development strategy "big health industry" and "healthy life destination" . This paper discussed the current situation and development prospect of the international development of TCM in Yunnan and the results helped to provide suggestion for the internationalision of TCM in Yunnan.