Peripherally inserted central catheter (PICC) in neonates is a commonly used technique in Neonatal Intensive Care Unit (NICU) . It is almost a necessary drug treatment and parenteral nutrition pathway for critically ill neonates, including very low birth weight premature infants. PICC safety management is related to nurses' practical ability. The National Association of Neonatal Nurses (NANN) formulated the Practice Guideline for PICC in Neonates and revised it into the Practice Guideline for PICC in Neonates (Third Edition) in 2015, in order to guide the bedside nursing practice of neonatal PICC and promote neonatal safety. In order to facilitate clinical nurses to guide clinical practice according to this guideline, the contents of this guideline are interpreted.

Neonatal skin care is still an important aspect of newborn care. At present, although there are nursing standards for various types of neonatal skin problems, there are different reports on complete evidence-based neonatal skin care practices. The American Association of Women's Health, Obstetric and Neonatal Nurses (AWHONN) developed and published the fourth edition of the Evidence- based Clinical Practice Guideline for Neonatal Skin Care in 2018. The guideline gives detailed guidance on the assessment of neonatal skin, identification of risk of neonatal skin damage, intervention of neonatal skin care, method of promoting neonatal skin development, and treatment of neonatal skin damage. However, nurses in China know little about this guideline. In order to facilitate nurses' understanding and application of this guideline to guide clinical practice, the content of this guideline is specially interpreted.