1.Effects of moxibustion on six acupoints around the knee on prevention of perioperative acute deep venous thrombosis of the lower extremity in patients undergoing total knee arthroplasty
Yinzhen FENG ; Suzhen HUANG ; Rongzong LIAO ; Yaocheng PAN ; Yuejing FENG ; Chunshao FENG
Chinese Journal of Modern Nursing 2020;26(36):5080-5085
Objective:To explore the preventive effect of moxibustion on six acupoints around the knee on perioperative deep venous thrombosis (DVT) of the lower extremity in patients undergoing total knee arthroplasty.Methods:Using the convenient sampling method, a total of 80 patients who underwent single total knee arthroplasty in Foshan Hospital of Traditional Chinese Medicine in Guangdong Province from January 2018 to October 2019 were selected as the research objects. According to the random number table method, they were divided into the control group and the observation group with 40 cases in each group. The control group was given conventional treatments and nursing such as subcutaneous injection of low molecular weight heparin calcium and the observation group was given moxibustion on six acupoints around the knee on the basis of the control group. Patients in the two groups were observed for 14 days. Changes in circumference difference of calf (before operation, 1, 7, 14 days after operation) , plasma prothrombin time (PT) , activated partial thromboplastin time (APTT) and D-dimer were compared between two groups. DVT formation was compared between the two groups on the 14th day after surgery and satisfaction of patients was evaluated.Results:The differences in calf circumference of the operating limbs within each group were statistically significant on the first day after operation and before operation ( P<0.05) . There were statistically significant differences between the 7th and 14th day after operation and the first day after operation ( P<0.05) . There was no statistically significant difference in calf circumference difference between the two groups before and on the first day after the operation ( P>0.05) . The differences between the two groups on the 7th and 14th day after operation were statistically significant ( P<0.05) . There were statistically significant differences in PT, APTT and D-dimer on the first day after surgery and before surgery within each group ( P<0.05) , and there were statistically significant differences between the 7th and 14th day after surgery and the first day after surgery ( P<0.05) . There was no statistically significant difference in PT, APTT and D-dimer before operation and on the 1st and 7th day after operation between the two groups ( P>0.05) . On the 14th day after operation, the differences of PT, APTT, D-dimer between the two groups were statistically significant ( P<0.05) . A total of 6 patients (15.0%) in the control group had DVT, but no DVT occurred in the observation group, the total satisfaction rate of the observation group was higher than that of the control group, and the differences were statistically significant ( P<0.05) . Conclusions:Moxibustion on six acupoints around the knee can reduce the swelling of the lower limbs after operation, improve coagulation function and prevent the occurrence of DVT, which has higher satisfaction of patients.
2.Application of combined detection of PCT ,hs-CRP ,IL-6 and WBC in diagnosing type 2 diabetes mellitus bloodstream infection
Xueqin FENG ; Runjie WU ; Lanfen LU ; Juan WANG ; Lishao MIAO ; Haizhong YAN ; Xihua LUO ; Yuejing MU ; Yang LI
International Journal of Laboratory Medicine 2018;39(2):169-172,175
Objective To investigate the application value of single detection and combined detection of 4 kinds of inflammatory indicators of procalcitonin (PCT ) ,high sensitivity C-reactive protein(hs-CRP) ,interleu-kin-6(IL-6) and white blood cell(WBC) in diagnosing type 2 diabetes mellitus(T2DM) bloodstream by analy-zing the levels of peripheral blood PCT ,hs-CRP ,IL-6 and WBC in the T2DM bloodstream infection group and T2DM non-bloodstream infection group .Methods The clinical data in 85 patients with T2DM bloodstream in-fection (T2DM bloodstream infection group ) and contemporaneous 80 cases of T2DM non-bloodstream infec-tion(T2DM non-bloodstream infection group) in this hospital from January 2013 to July 2016 were retrospec-tively analyzed .The levels of various inflammatory indicators in peripheral blood were analyzed .The receiver operating characteristic(ROC) curve of various inflammatory indicators was drawn ,the area under the curve (AUC) and the best cut-off value were calculated .The detection schemes included 24 kinds of schemes such as the single indicator ,2-indicator ,3-indicator and 4-indicator .Results The levels of PCT ,hs-CRP ,IL-6 and WBC in the T2DM bloodstream infection group were significantly higher than those in the T 2DM non-blood-stream infection group ,the difference was statistically significant (P<0 .05) .AUC of PCT ,hs-CRP ,IL-6 and WBC were 0 .909 ,0 .818 ,0 .838 and 0 .760 respectively ,with best cut-off values of 0 .493 ng/mL ,11 .19 ng/mL ,40 .95 pg/mL and 11 .87 × 109/L respectively .The Youden index of PCT was highest (0 .65) and the ac-curacy of IL-6 was highest (83 .33% ) in the single indicator detection scheme .The Youden index and accuracy of the scheme of PCT/hs-CRP and PCT+hs-CRP+IL-6 were highest in the combined detection scheme .Con-clusion PCT detection has the prominent value in the assisted diagnosis of T 2DM bloodstream infection .Inthe combined detection scheme ,PCT/hs-CRP and PCT+hs-CRP+IL-6 have the highest value in the assisted diagnosis in T2DM bloodstream infection .