1.Effect of Naoxinqing Tablet for Cerebral Atherosclerosis and Angina Pectoris of Coronary Heart Disease: An Observation of 60 Cases
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(06):-
To assess the effect and the safety of Naoxinqing Tablet in treating cerebral atherosclerosis and angina pectoris of coronary heart disease. Forty-eight patients with cerebral atherosclerosis and 12 patients with angina pectoris of coronary heart disease served as the objects. The effective rates were 83.33% and 75.00% in cerebral atherosclerosis group and angina pectoris of coronary heart disease group respectively, and the total effective rate of Naoxinqing Tablet was 81.67%, the difference being significant as compared with those before treatment (P
2.Laparoscopic splenectomy performed in 41 cases
Xianfa WANG ; Xiujun CAI ; Hong YU ; Yuedong WANG ; Xiao LIANG ; Wei LI
Chinese Journal of General Surgery 2001;0(10):-
Objective To evaluate the feasibility and efficacy of laparoscopic splenectomy(LS). Methods In this study 41 cases were enrolled including 10 cirrhotic splenomegaly cases and 17 idiopathic thrombocytopenic purpura cases. The clinical data of 41 cases undergoing LS was retrospectively reviewed. KG2Result Two cases were shifted to open surgery, LS was successful in 39 cases with average operating time of 238 min, the average spleen weight was 389 g, blood loss 318 ml, postoperative GI movement started from 12 to 24 hrs. The average postoperative hospital stay was 4 days. Postoperative complications occurred in 3 cases including intraabdominal bleeding, subcutaneous emphysema, and stabbing-caused abdominal wall bleeding in one each. Conclusion LS is safe and less traumatic in selected patients indicated for splenectomy, especially for those suffering from haemotologic diseases.
3.EST pipeline system: detailed and automated EST data processing and mining.
Hao XU ; Ling HE ; Yuanzhong ZHU ; Wei HUANG ; Lijun FANG ; Lin TAO ; Yuedong ZHU ; Lin CAI ; Huayong XU ; Liang ZHANG ; Hong XU ; Yan ZHOU
Genomics, Proteomics & Bioinformatics 2003;1(3):236-242
Expressed sequence tags (ESTs) are widely used in gene survey research these years. The EST Pipeline System, software developed by Hangzhou Genomics Institute (HGI), can automatically analyze different scalar EST sequences by suitable methods. All the analysis reports, including those of vector masking, sequence assembly, gene annotation, Gene Ontology classification, and some other analyses, can be browsed and searched as well as downloaded in the Excel format from the web interface, saving research efforts from routine data processing for biological rules embedded in the data.
Automation
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Base Composition
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Computational Biology
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methods
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Databases, Genetic
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Expressed Sequence Tags
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Software
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User-Computer Interface
4.Classification Tree Model Analysis on Risk Factors of Diabetic Kidney Disease to Progress to ESRD for CKD3-4 Stages Patients
Zhi-bo LIAO ; Xun LIU ; Cai-lian CHENG ; Cheng-gang SHI ; Shao-min LI ; Wen-bo ZHAO
Journal of Sun Yat-sen University(Medical Sciences) 2019;40(5):767-773
【Objective】To analyze the risk factors of progression to end-stage renal disease(ESRD)in patients with
diabetic kidney disease(DKD),and screen the high-risk population for early prevention.【Methods】The clinical data of
231 patients with diabetic nephropathy in our hospital were collected and followed up for 3 years. According to whether
ESRD occurred,they were divided into non-progressing ESRD group(133 cases)and ESRD group(98 cases). Classification
tree model was used to analyze the risk factors related to ESRD,and the high-risk population was screened by node gain
analysis.【Results】Four important explanatory variables were screened out by the classification tree model from the candi⁃
date variables related to early renal damage,including apolipoprotein B(ApoB),gender,diabetic retinopathy,systemic blood
pressure(SBP). ApoB level was an important factor for DKD progression. For DKD patients with the chronic kidney disease
(CKD)3~4 stageswith ApoB> 1.14 mmol/L,theprobabilityofprogression toESRDfor 3 yearswas 75.0 %,and ifat the same
time with diabetic retinopathy,the probability was 79.7 %.【Conclusion】The classification tree model can analyze the risk
factors of progression to ESRD in DKD patients effectively,to identify the characteristics of high-risk populations.
5.Effects of Dual-task Motor Training with Anti-gravity Treadmill on Motor and Balance after Stroke
Qing CAI ; Lijun XIE ; Junlv ZHAO ; Pengying YE ; Minzhi SU ; Shuxian ZHANG ; Huigang GAO ; Xiquan HU ; Xi CHEN
Chinese Journal of Rehabilitation Theory and Practice 2018;24(11):1315-1319
Objective To observe the effects of dual-task motor training on motor and balance function for stroke patients. Methods From January, 2016 to June, 2017, 30 patients with stroke were assigned randomly into control group (n = 15) and treatment group (n = 15). Both groups accepted routine physical therapy, the control group accepted anti-gravity treadmill training, while the treatment group accepted dual-task training with anti-gravity treadmill, for four weeks. They were measured with balance training and evaluation system, and assessed with Fugl-Meyer Assessment-lower extremity (FMA-L), Berg Balance Scale (BBS) and modified Barthel Index (MBI), before and after treatment. Results The range of swaying on X axial (Rx) and Y axial (Ry), as well as rectangle area (RecArea) decreased after treatment in the treatment group (t > 4.719, P < 0.001), while RecArea decreased in the control group (t = 5.069, P < 0.001). Ry and RecArea were less in the treatment group than in the control group (t > 2.288, P < 0.05). The scores of FMA-L, BBS and MBI improved after treatment in both groups (t > 7.316, P < 0.001), and improved more in the treatment group than in the control group (t > 2.322, P < 0.05). Conclusion The dual-task training via anti-gravity treadmill may improve motor and balance function in stroke patients, and promote the activities of daily living.