Purpose:To study the efficacy and the side ef fe ct of morphine controlled-release tablets plus diclofenac sodium in the treatme nt of pain of metastatic bone carcinoma. Methods:69 patients with pain were randomly divided into two gr oups. Group Ⅰ was treated only with morphine controlled-release tablets (30 mg ,q 12 h),GroupⅡ with morphine controlled-release tablets (30 mg,q 12 h) and diclofenac sodium (100 mg,q 12 h). The analgesia effect and adverse reaction were observed. Results: Both have analgesia effect,but group Ⅱ was superior (P