1.2 Schemes for Ischemic Cerebral Infarction:Cost-Effectiveness Analysis
China Pharmacy 1991;0(02):-
0.05),and 12 928.75 vs.14 262.98,respectively.Both groups had 1 alimentary tract hemorrhage case in either group but were cured on treatment.No intracranial hemorrhage was noted in either group.CONCLUSION:Yinxingdamo injection was an optimal therapy as compared with Shuxuening.
2.Cost-Effectiveness Analysis of Cefoperazone Sodium/Sulbactam Sodium vs. Levofloxacin in the Treatment of Community Acquired Pneumonia
China Pharmacy 2001;0(08):-
0.05) and the cost-effectiveness ratios were 1 898.85 and 1 599.81,respectively.CONCLUSION:Levoflocaxin is superior to cefoperazone sodium/sulbactam sodium for community acquired pneumonia.
3.Expression of bad gene in human optic nerves from traumatic atrophic eyes
Dongkan LI ; Yue SONG ; Yue ZHANG
Chinese Journal of Ocular Fundus Diseases 2000;0(04):-
Objective To study the expression and its significance of bcl-2 associated death (bad) gene in human optic nerves from traumatic atrophic eyeballs. Methods The optic nerves from 8 normal human donor eyes and 31 traumatic atrophic eyes were studied by immunohistochemistry technique. Results Bad protein was positively expressed in the normal optic nerve myelin sheath and residual myelin portions of optic nerve tissues from traumatic atrophic eyes. The expression of bad protein in the residual portions of myelin sheath was stained significantly stronger than that in normal optic nerves (P0 05). Conclusion Bad might possess the function of promoting the optic nerve atrophy processes in traumatic atrophic eyes.
5.Aldo-keto reductase superfamily and lung cancer
Journal of International Oncology 2013;(1):43-46
Aldo-keto reductase reductase (AKR) superfamily is NADPH-dependent oxidoreductase.As a rate-limiting enzyme in polyols metabolic pathway,the activation or inactivation of AKR involves in neoplastic process of lung cancer with the metabolism of environment toxic.AKR is related to drug resistance of chemotherapy,which will be the prognostic factor of lung cancer.
6.Clinical Analysis of 124 Children with Henoch-Sch(o)nlein Purpura
Journal of China Medical University 2010;(1):58-60
Objective To study the clinical characteristics of Henoch-Sch(o)nlein purpura (HSP) in children.Methods We retrospectively analyzed the clinical data of 124 children with HSP.Results Among these 124 children,54.84% of the children presented upper respiratory tract infection before the onset of HSP.The purpura recurred in 30 of 47 children with Henoch-Sch(o)nlein purpura nephritis and in 22 of 77 children without Henoch-Schonlein purpura nephritis,respectively (P<0.05).The incidence of Henoch-Sch(o)nlein purpura nephritis was significantly higher in children who had purpura,gastrointestinal symptoms,and joint symptoms simultaneously than in those only with purpura (P<0.05).The elevated levels of IgA and C reactive protein were found in 67.35% and 39.39% of the children,respectively.Conclusion The most important predisposing factor of HSP is upper respiratory tract infection.The children with recurrence of purpura or those who have purpura,gastrointestinal symptoms,and joint symptoms simultaneously are more likely to present renal damage.
7.Advances in diagnosis and treatment of Takayasu arteritis in children
International Journal of Pediatrics 2013;(3):297-300
Takayasu arteritis (TA) is a devastating vasculitis of the aorta and its major branches,coronary and pulmonary arteries.The clinical manifestations in children are less specific than in adnlts:the disease in children presents with fever,arthralgias,vomiting,weight loss and hypertension.Conventional angiography,which is recognized as the golden standard in evaluating vascular lesions in TA,combined with computer tomography angiography (CTA),magnetic resonance angiography (MRA),ultrasonography,could not only provide important information for early diagnosis,but also detect disease activity.New immunosuppressive agents and biological therapies,such as TNF-a blocking agents,have been verified to be effective although corticosteroids and conventional immunosuppressive agents are still basic treatment.
8.Tumor microenvironment and tumor
Journal of International Oncology 2013;40(8):582-584
Rational microenvironment contributes actively to cancer development through multiple mechanisms including triggering genomics instability,providing shield,promoting immune escape,inducing differentiation and permissive nich.Tumorigenesis reversely promotes the form of tumor microenvironment composed of hypoxia,decreasing pH,angiogenesis and nutrition deficiency.Tumor microenvironment not only is the reasons but also results in cancer development and progression.A better understanding of how the tumor environment affects cancer progression would provide the new strategy for cancer therapy.
9.Current status of laparoscopic therapy of severe acute pancreatitis
International Journal of Surgery 2012;39(6):412-415
The surgical intervention and criteria of severe acute pancreatitis has significantly changed in the last several years with the advent of enhanced imaging techniques and minimally invasive surgery.Many kinds of minimally invasive technologies which take laparoscopy as a representative are constantly applied to the treatment of severe acute pancreatitis and make its mortality and postoperative complication rate decrease obviously.However,there are many different ways using laparoscopic techniques to treat severe acute pancreatitis.In this review,the author will discuss the current status of the different approaches.
10.Molecular classification of breast cancer
Journal of International Oncology 2014;41(4):270-272
Breast cancer is a group of heterogeneous diseases.Molecular portraits provide a new insight for personalized cancer management in breast cancer.According to the molecular pathology,molecular biology and system biology,breast cancer goes through different typing methods,including four subclasses,geneexpression signature and integrated genomic classification.These major subtypes of breast cancer may provide guidance for precise therapeutics.