0.05),and 12 928.75 vs.14 262.98,respectively.Both groups had 1 alimentary tract hemorrhage case in either group but were cured on treatment.No intracranial hemorrhage was noted in either group.CONCLUSION:Yinxingdamo injection was an optimal therapy as compared with Shuxuening.

0.05) and the cost-effectiveness ratios were 1 898.85 and 1 599.81,respectively.CONCLUSION:Levoflocaxin is superior to cefoperazone sodium/sulbactam sodium for community acquired pneumonia.

Objective To study the expression and its significance of bcl-2 associated death (bad) gene in human optic nerves from traumatic atrophic eyeballs. Methods The optic nerves from 8 normal human donor eyes and 31 traumatic atrophic eyes were studied by immunohistochemistry technique. Results Bad protein was positively expressed in the normal optic nerve myelin sheath and residual myelin portions of optic nerve tissues from traumatic atrophic eyes. The expression of bad protein in the residual portions of myelin sheath was stained significantly stronger than that in normal optic nerves (P0 05). Conclusion Bad might possess the function of promoting the optic nerve atrophy processes in traumatic atrophic eyes.

Acute Lung Injury ; chemically induced ; pathology ; Animals ; Humans ; Lung ; pathology ; Nanospheres ; adverse effects ; Titanium ; adverse effects

Anticonvulsants ; administration & dosage ; therapeutic use ; Drug Prescriptions ; Humans ; Off-Label Use

OBJECTIVE:To investigate the possible mechanism of the neuroprotective action of isatin(ISA).METHODS:A total of 40 C57BL/6J mice were divided into 4 groups:control group,model group,ISA(200 mg?kg-1 intragastrically) group,and selegiline(0.5 mg?kg-1 intraperitoneally) group.After pretreatment with drugs for 10 days,the latter 3 groups were given 1-methyl-4-phenyl-1,2,3,6-tetrahyrdropyridine(MPTP) intraperitoneally to establish Parkinson's disease(PD) model,then the mice were put to death for the determination of the activities of MAO-B,SOD and GSH-px in blood serum and brain tissue.RESULTS:As compared with blank control group,the activity of MAO-B in model group increased slightly,while the activities of SOD and GSH-px decreased(P

Objective To explore the role of phosphatidylinositol 3-kinase/protein kinase B(PI3K/AKT) pathway in recombinant human erythropoietin( rhEPO) protecting new type BPD. Methods Injected LPS or PBS to 40 spra-gue-dawley (SD) rats, gestational sacs on 15th day of gestation, the newborn rats were divided into four groups:control group, hyperoxia group, rhEPO group, rhEPO+LY294002 group. To detect the expression of lung tissue BCL-2 and Caspase - 9 protein and mRNA by Western blot and RT-PCR. Results In the hyperoxia group and rhEPO+LY294002 group, BCL-2 expression was decreased,while Caspase-9 expression was increased apparently;in the rhEPO group, BCL-2 expression was increased, while Caspase-9 expression was decreased. The differences between each group were statistically significant on 1st,7th and 14th day of hyperoxia exposure (P<0. 05). Con-clusion Intrauterine inflammatory exposure combined with hyperoxia after birth can cause lung cell apoptosis in-creases. While rhEPO has certain control effects on BPD, possibly by reducing the pulmonary apoptosis. The mechanism may be associated with PI3K/AKT signaling pathway.

Diabetic retinopathy (DR) is one of the most significant microvascular complications of diabetes,and its incidence increases with the prolongation of DM;meanwhile,it can lead to severe vision loss.Recently,the pathogenesis of DR has been one of the focuses both at home and abroad,but the basic mechanisms are not fully elucidated.More and more scholars believe that DR may be a chronic and low degree of inflammatory response.Moreover,it is well established that microglia is a monocyte-macrophage,with antigen-presenting function.Especially in the retina,as microglia is activated,followed by the release of a large number of inflammatory factors,microglia involves in DR inflammatory response.Understanding the activation mechanism of microglia can provide a new perspective for the prevention and treatment of DR.Therefore,recent advances in activation of microglia in diabetic retinopathy and its intervention mechanism will be reviewed in the article.

The similar mechanism of human cancer and aging means that cancer is the natural result of aging.Mitochondrial replacement, genome editing, telomere synthesis and immune editing can induce cancer cell senescence and resist human aging, which may breach a limit to human lifespan.

Objective To develop a lossless compression algorithm applied on the MCU.Methods Direct difference data compression and 2-4-8 three-word-length coding data compression based on the first order difference were developed.Statistics on the results of the first order difference of ECG data in the MIT_BIH ECG database resulted in an optimal three-word-length code table.Results Direct difference data compression ratio was lower than 2,and three-word-length data compression ratio was around 3.Conclusion There are both advantages and disadvantages in two types of lossless data compression,but three-word-length data compression is superior to direct difference data compression.[Chinese Medical Equipment Journal,2008,29(2):24-27]