Objective To evaluate the feasibility and safety of stent implantation in treating patients with symptomatic vertebral artery kinking.Methods Thirty-six patients with vertebral artery kinking confirmed by DSA and accorded with the stent implantation indications were chosen in our study;these patients were performed stent implantation.The stenosis and haemodynamics changes,and recent and postoperative complications were observed; Malek scale was adopted to evaluate the clinical efficacy during the 1-year follow-up.Results The success rate of stent implantation for patients with symptomatic vertebral artery kinking was 100％.The percentage of stenosis was significantly reduced from(76％±15％)to(8％±3％)after stenting(P＜0.05); the mean flow velocity of kinking lesion was obviously decreased from([45.4±22.3]cr/s)to([31.8±15.1]em/s,P＜0.05); cerebellum hematoma was noted in 1 patient subcutaneous hematoma of puncture point in 2 and femoral artery pseudoaneurysms after the stenting in 1; all these complications did not cause serious consequences.Malek scale indicated that 31 patients got 1 point,3 got 2 points,1 got 3 points,1 got 4 points and no one got 5 points; 31patients were asymptomatic during the 1-year follow-up; no significant in-stent restenosis was found.Conclusion Symptomatic vertebral artery kinking can be treated safely and effectively with stent implantation.

Oral squamous cell carcinoma (OSCC) is the most common oral malignancy. It has a high incidence, strong invasion ability, easy metastasis, poor curative effect, and poor prognosis. Innate lymphoid cells (ILCs) are an important part of immune cells located in the mucosal barrier, which play an important role in the occurrence, development and outcome of tumors. ILCs are the key cells for decoding the regulatory mechanism of tumor microenvironment and the signatures for tumor progression. This paper reviewed the latest progress on ILCs, summarized the possible characteristics and functions of ILCs in the microenvironment of OSCC, and explored the relationship between ILCs and the occurrence, development and immunotherapy of OSCC.

Objective:To explore the clinical value of high frequency color Doppler ultrasound in the diagnosis of upper limb nerve disease.Methods:The inspection of 32 patients with upper limb nerve disease was performed by high frequency color Doppler ultrasound.Through observing the upper limb nerve continuity, epineurium, nerve bundle, surrounding tissues, the nerve-associated mass and their relevance, the type and location of neurological diseases were confirmed, and the ultrasonographic features were analyzed and compared with those of the healthy side.Results:Fourteen cases showed single schwannoma, whose image characteristics were priority to elliptic low echo, clear boundary, the envelope.Six cases showed neurofibromatosis;among them, 5 cases with single neurofibroma showing low echo, internal uniform, fusiform shape, and the ends connected with the nerves;other 1 case with multiple and beaded neurofibroma.Three cases showed ulnar neuritis with local nerve thickening, echo reduction, hypoechoic cross-section, "screen mesh shape" structure disappearing, and abundant blood flow signals on CDFI.Nine cases showed traumatic nerve injury, whose local nerve was compressed and morphologically abnormal, with irregular abnormal echo around region.Conclusions:The different upper limb nerve diseases have different characteristic ultrasonography, and high frequency color Doppler ultrasound may provide the preferred image basis for clinical diagnosis and treatment.