1.Endoscopic mucosal resections and follow-up study for 8 patients with colonic laterally spreading tumors with early carcinomatous change
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
Objective To eraluate the methods and results of endoscopic mucosal resections for colonic laterally spreading tumors with early malignant degeneration. Methods The pit pattern was studied with magnitying colonoscopy and mucosal staining technique for colonic laterally spreading tumors (LST) undergoing early earcinatous degeneration. They were removed with endoscopic mucosal resection techniques. A follow-up study was made. Results Eight patients suffering from early carcinoma on top of colonic laterally spreading tumors were followed-up. ① 75% of the lesions were situated in the rectum, sigmoid colon and decending colon. ② 75% of the lesions were larger than 30mm in diameter. ③ 75% of the lesions belonged to Ⅳpit pattern. ④ 62.5% of the lesions were Villous adenomas and 75% of the onalignant change involved the mucosa only. ⑤ All the lesions were completely removed by EMR, ⑥ No local residual lesion, recurrence or metastasis was discovered in all the patients after a mean follow-up period of 20.7 months. Conclusions Most of the early carcinomas originated from colonic LST involved the mucosa only. Endoscopic mucosal resection may be a curative method for the early cancer arising from colonic LST.
3.Comparative study on bio-activity of polysaccharide from Pinus massoniana pollen and its sulfated derivative
Yue GENG ; Hui LIU ; Lihua SHI ; Zhihe LIU
Chinese Journal of Biochemical Pharmaceutics 2010;31(2):98-102
Purpose To study the polysaccharide from Pinus massoniana pollen(PPM)and to compare its anti-tumor,immune modulation activities and scavenging qualities of free radical with its sulfated derivative(S-PPM).Methods PPM Wag chemically modified by chlorosulfonic acid-pyfidine method and their bioactivities were compared.Results The substituting degree of S-PPM was 1.47.Results showed that S-PPM was more powerful in inhibiting the growth of tumor cell in vivo and in vitro and in promoting T,B lymphocytes than PPM.But there Wag no remarkable difference in promoting phagocytosis of macmphages.S-PPM was stronger in scavenging superoxide anion radical than PPM but it wag vice versa in scavenging hydroxyl radical.Conclusion S-PPM inhibited the cancer cell growth mainly through specific immunity.Sulfate of PPM influenced its quality of scavenging free radicals greatly.
4.Inhibitory effect of nicotinylsalicylic acid on rabbit platelet aggregation induced by ADP,AA and Collagen
Minheng ZHU ; Yue WU ; Hong CHEN ; Hui TIAN ; Honghai LIU
Chinese Pharmacological Bulletin 2003;0(10):-
Aim To investigate the effect of nicotinyl salicylic acid(NSA) on rabbit platelet aggregation induced by Collagen,ADP and AA.Methods Platelet aggregation induced by collagen,adenosine diphosphate(ADP) or arachidonic acid(AA) was studied with turbidimetry in rabbtis blood,in vitro and vivo.Results NSA significantly inhibited the platelet aggregation induced by Collagen and ADP,in vitro and vivo.The inhibition by NSA was dose-dependent.NSA had no effect on the platelet aggregation induced by AA.Conclusion NSA can inhibit rabbit platelet aggregation induced by Collagen and ADP.
5.Lower respiratory tract of pneumoconiosis on fosfomycin antibacterial activity in vitro of fosfomycin to infected in coal worker pneumoconiosis in vitro antibacterial activity.
Pei-Yue LIU ; De-Quan GU ; Kai-Hui ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2011;29(7):547-548
Acinetobacter Infections
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microbiology
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Acinetobacter baumannii
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drug effects
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isolation & purification
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Anthracosis
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microbiology
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Anti-Bacterial Agents
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pharmacology
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Drug Resistance, Bacterial
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Fosfomycin
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pharmacology
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Humans
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Imipenem
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pharmacology
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Pneumonia, Bacterial
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microbiology
6.Summary of Hui prescriptions for treating cough.
Wen-jin ZHANG ; Yue LIU ; Xin-hui ZHANG
China Journal of Chinese Materia Medica 2015;40(4):753-757
In this study, by using the method of literature research, 35 prescriptions related to asthma therapy has been screened out from Hui medicine through collecting the ancient and modern literature. A comparison of fragrant medicine between the name in Arab and Chinese herbal medicine is done. The countif function in Microsoft Excel 2007 is used to get the prescriptions of the drug on the frequency statistics, summarizing the common drugs of Hui medicine for asthma are Pinellia, almond, white sugar, walnut. According to the commonly used drugs, the pathogeny and treatment principle about Hui medicine for asthma is preliminarily inferred combining literature research and the related Hui medical theory. In this study, those prescriptions have been classified into 21 cases which are effective and can be used in medical therapy according to the relevant literatures with the development of the Hui people in their long process of formation of the unique diet culture, 14 useful and convenient Halal diet therapies are made up according to the indications, therapies, party name and composition. Halal diet and "medicine and food" herbs are preliminarily analyzed and summarized, which can be convenient for the people to reduce pains through the diet and improve health awareness.
Asthma
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drug therapy
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ethnology
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China
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Cough
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drug therapy
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ethnology
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Diet
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ethnology
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Drug Prescriptions
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Drugs, Chinese Herbal
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chemistry
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therapeutic use
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Humans
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Medicine, Chinese Traditional
7.A nested case-control study of influencing factors of chronic brucellosis
Yue ZHAO ; Ying WANG ; Zhanli WANG ; Hui YU ; Chunfang LIU
Chinese Journal of Endemiology 2015;34(6):450-451
Objective To investigate the influencing factors of chronic brucellosis.Methods Nested case control method was used to study newly diagnosed patients (n =600) with brucellosis in a cohort study in 2012.Data of general characterstics,clinical presentation,treatment and prognosis of those patients were collected.These patients were followed up for one year,and the chronic patients as the case group (n =248) and the healed patients as a control group (n =260).By means of Logistic multivariate analysis,factors turned brucellosis into chronic were screened.Result The chronic brucellosis-related factors were:gender,veterinary or epidemic prevention staff,muscle and joint pain,fatigue symptoms,and substandard treatment (x2 =5.163,16.445,14.977,17.154,8.813,all P < 0.05).Conclusion Gender (female),veterinary or epidemic prevention staff,muscle and joint pain,fatigue symptoms,and substandard treatment are probably the chronic brucellosis-related factors
8.The relationship between hepatitis B virus pre-S gene mutations and progression of liver disease
Jing-Juan DING ; Mei WANG ; Yue-Hui LIU ;
Chinese Journal of Infectious Diseases 2001;0(06):-
Objective To study the relationship between hepatitis B virus(HBV)pre-S gene mutations and progression of liver disease.Methods The entire pre-S1,pre-S2 genes were amplified hy nested polymerase chain reaction(PCR)and the products were digested by NlaⅢ.The method for detecting pre-S2 start codon mutation was established based on the digested restriction fragment length polymorphism(RFLP).Pre-S gene deletion was revealed by electrophoresis on polyacrylamide gel(PAGE).Pre-C A1896 and basic core promoter T1762/A1764 mutations were identified by direct sequencing of PCR products.The 138 sera from patients with HBV-related disease,including asymp- tomatic carriers(ASC),chronic hepatitis(CH),liver cirrhosis(LC),hepatocarcinoma(HCC),were tested by these methods.Results The detection rate of pre-S deletion mutation was higher in patients with HCC(56.3%)and LC(42.9%)than those with CH(11.8%)and ASC(8.1%,P
9.The investigation of the university and secondary school students' cognition of wetland protection in Jining
Xitong YUE ; Ye SONG ; Min ZHAI ; Liming SUI ; Hui LIU
Chinese Journal of Medical Education Research 2006;0(09):-
Objective Through the investigations of university students’and middle school students’ grasping situation of wetland elementary knowledge and their attitude toward wetland protection,the situation in propaganda and education of wetland protection and the congnition of wetland function,to identify some problems and to adopt the corresponding measures. Methods Using the stratified cluster sampling method, a questionnaire survey was carried out among 480 students of two urban and rural middle school and two universities. Results There were significant differences on the farmiliar degree to basic concepts of wetland protection,the methods of acquiring wetland knowledge and the understanding of wetland function among the urban and rural middle school students, arts and science university students. Conclusions The study subjects have many shortages in the consciousness and knowledge of wetland protection, and the special propaganda and education of the wetland protection should be carried out.
10.Exploration and reflection of the education model of environmental hygiene
Min ZHAI ; Xitong YUE ; Hui LIU ; Ye SONG
Chinese Journal of Medical Education Research 2006;0(08):-
With the reform of means and methods of teaching,experimental teaching and the establishment of training bases of environmental hygiene,a survey of teaching effects and demands among the students of preventive medicine was conducted through questionnaire,in order to explore the appropriate way for environmental education.