OBJECTIVE:To facilitate the construction of Chinese pharmaceutical profession associations. METHODS: We analyzed the current situation and problems existing in Chinese pharmaceutical profession association as well as the developmental experience of foreign pharmaceutical associations then put forward suggestions for the development of pharmaceutical profession associations in China. RESULTS & CONCLUSIONS: The sound development of pharmaceutical profession associations calls for the cooperated efforts of government, profession association and pharmaceutical enterprises, meanwhile its function as bridge and tie between pharmaceutical enterprises and government should be brought into full play.

Arthralgia ; etiology ; Arthroplasty, Replacement, Knee ; adverse effects ; Humans ; Knee Joint ; surgery ; Pain, Postoperative ; etiology

Humans ; Pulpitis ; diagnosis

Chronic Disease ; Cone-Beam Computed Tomography ; Humans ; Periapical Abscess ; pathology ; Periapical Granuloma ; pathology ; Periapical Periodontitis ; diagnostic imaging ; pathology ; Problem Solving ; Prognosis ; Radicular Cyst ; diagnostic imaging ; pathology

Excitatory Amino Acids ; secretion ; Humans ; Neurotransmitter Agents ; secretion ; Pain, Postoperative ; etiology ; metabolism ; prevention & control

The foundation of neonatal arrhythmia is the immature heart conduction system. Common causes include neonatal organic heart disease (infectious myocarditis, myocardial injury, and congenital heart disease); neonatal infectious diseases; neonatal asphyxia; electrolyte imbalance, acidosis, and drug overdose. According to different arrhythmia (premature constractions,paroxysmal superventricular tachycardia,chaotic atrial tachycardia,completely conduction block),the patients should be treated in different measures. Managements include original disease treatment, removal of incentives, add with anfi-arrhythmic drugs, and protection of myocardial.

ObjectiveTo master the condition of work environment and job satisfaction in Dongying district,as well as the relationship between them in order to provide a scientific basis for improving the morale of nurses and stable nursing position in this region. Methods760 clinical nurses of 5 hospitals of grade-two level in Dongying district were randomly selected.The survey was carried out with questionnaire. ResultsIn the aspect of work environment,the lowest score was the cultural sensitivity and practice control,in the aspect of job satisfaction,the most dissatisfying was the benefits.The impact factors of work environment included leadership and autonomy,internal work motivation,control of practice,work stress and doctor-nurse relationship.The personal factors affecting satisfaction included professional title,age,working years. ConclusionsIt is recommended to take effective measures to improve nursing work environment to improve job satisfaction degree of nurses.

The mechanism of drug resistance of refractory epilepsy has remained unclear.In recent years,studies have shown that the multi-drug resistance associated protein(MRP) is related with refractory epilepsy.The mechanism responsible for the drug resistance may have something to do with the higher expression of MRP1 mRNA in brain tissues of refractory epilepsy patients.Through the use of drugs in cells to cells from the pump,it can reduce the drug concentration in brain and make the creation bears the medicine and inhibitors specific for MRP,which can significantly improve the effect of some antiepileptic drugs.Thus,further studies may provide new ways for the treatment of refractory epilepsy and find targets for new antiepileptic drugs.

10.3969/j.issn.2095-4344.2013.24.023

Objective To investigate the clinical efficacy of amlodipine combined with atorvastatin in treatment of hypertensive patients complicated with coronary heart disease.Methods 80 hypertension patients complicated with coronary heart disease were randomly divided into the observation group 40 cases,control group 40 cases.Control group was given amlodipine treatment,the observation group was given amlodipine and atorvastatin calcium therapy.The clinical efficacy of two groups were compared.Results The hypertension excellent and good rate of the observation group was 95.0％,77.5％ in the control group.The excellent and good rate of coronary heart disease in the observation group was 87.5％,75.0％ in control group.The excellent and good rate of hypertension and coronary heart disease between two groups had statistically significant differences(x2 =23.12,18.98,all P ＜ 0.05).The incidence rate of adverse reaction in observation group was 10％,control group 10％,which showed no significant difference between the two groups (P ＞ 0.05).Conclusion Amlodipine combined with atorvastatin calcium has the exact clinical efficacy in the treatment of hypertension and coronary heart disease,it can improve the patients' quality of life and worthy of clinical application.