Objective? To investigate the status quo of knowledge, attitude and practice (KAP) about palliative wound care in wound nurses, to analyze its influencing factors and to lay a basis for the development of palliative wound care. Methods? Totally 183 wound nurses were selected using convenient sampling from June to August 2018 and investigated with the general information questionnaire and KAP scale for palliative wound care. Univariate analysis and multivariate linear regression analysis were used to analyze the influencing factors to KAP. Results? The knowledge score of the wound nurses was (5.75±1.58), with a pass yield of 59.02%; the attitude score was (26.07±3.22), and the practice score was (29.20±7.05). Multivariate linear regression analysis showed that the influencing factor to wound nurses＇ knowledge about palliative wound care was their length of service dedicated to wound care (P＜ 0.05); the influencing factors to their attitude were their length of service dedicated to wound care, role in the wound care team, and whether to attend further education in wound care (P＜ 0.05); the influencing factor to their practice was their role in the wound care team (P＜ 0.05). Conclusions? Wound nurses＇ knowledge about palliative wound care stands at a low level. Their attitude is positive, but their practice is poor. Relevant knowledge and skill training shall be organized and the opportunities to attend various academic meetings and lectures should be provided to improve their clinical wound care.