Objective To know the pollution situation by microcystin MC in Tai Lake in Wuxi. Methods The MC content in 12 water samples and 28 fish samples in the Tai Lake were determined by ELISA. Results The positive rates of MC in water samples and fish samples were 100%. The mean content of MC in water samples was higher in July 9 874.8 pg/ml than in November 142.8 pg/ml. The mean content of MC in the livers was 27.84 ng/g, in the muscle it was 3.97 ng/g. Conclusion The Tai Lake has been contaminated by microcystin and it can be detected in the fish living in the lake.

Objective To evaluate the effect of community systemic management on quality of life in patients with hypertension.Methods A cross-sectional study was used to survey 224 patients with essential hypertension systemically managed in community and 205 non-management patients using the questionnaire including demographic information,behaviour,years of hypertension,treatment,Chinese version SF-36 short form of quality of life and the symptom distress checklist.Student-t test,?2-test,and covariance analysis was used in data analysis.Result The managed patients' mean score of knowledge(6.40?1.31)was significantly higher than that in non-managed patients'(5.02?1.82,t=8.82,P

Atherosclerosis(AS)is a chronic inflammatory disease of large and medium-sized arteries that leads to ischemic heart disease,stroke,and peripheral vascular disease.Despite the current treatments,mortality and disability still remain high.Sonodynamic therapy(SDT),a non-invasive and localized methodology,has been developed as a promising new treatment for inhibiting atherosclerotic progression and sta-bilizing plaques.Promising progress has been made through cell and animal assays,as well as clinical trials.For example,the effect of SDT on apoptosis and autophagy of cells in AS,especially macrophages,and the concept of non-lethal SDT has also been proposed.In this review,we summarize the ultrasonic parameters and known sonosensitizers utilized in SDT for AS;we elaborate on SDTs therapeutic effects and mechanisms in terms of macrophages,T lymphocytes,neovascularization,smooth muscle cells,lipid,extracellular matrix and efferocytosis within plaques;additionally,we discuss the safety of SDT.A comprehensive summary of the confirmed effects of SDT on AS is conducted to establish a framework for future researchers.

Objecgive To investigate the HB awareness,the infection rate of HBV and the immunity status among adults at the communities of Wuxi,and to provide some evidences for vaccination strategy.Methods Two communities were enrolled in the study through cluster sampling method.A household survey was conducted to collect subjects' information through a face-to-face interview and blood samples were collected to detect HBsAg,anti-HBs,HBeAg,anti-HBe and anti-HBc.Results 3744 subjects were enrolled in this study.The general knowledge coverage rate of hepatitis B was high and 87.30%respondents claimed that hepatitis B was an infectious disease.The percentage of subjects who got more than 5 scores in persons had got hepatitis B vaccination was 60.18%(239/393),and this was significantly higher than in those without vaccine inoculation(x2=17.07,P＜0.01),with the proportion being 49.49%(1071/2164).rnIe percentage of subjects who got more than 5 scores in persons had family history of HBV infection was 60.00%(318/530),and this wag significantly higher than in those without family history (x2=53.05,P＜0.01),with the proportion of 43.00%(1382/3214).The standardized HBV infection rate was 49.88%.There were 1109(29.62%)subjects whose HBsAg,anti-HBs,HBeAg,anti-HBe and HBcAg were negative.There were 8 subjects(0.21%) whose HBsAg,HBeAg and anti-HBc were positive simultaneously,and there were 133 subjects(3.55%)whose HBsAg,anti-HBe and anti-HBc were positive simultaneously.The positive rate of anti-HBc was significantly higher in males than in females( 59.37%and 53.08%,P=0.00).The positive rates of HBsAg,anti-HBs,HBeAg,anti-HBe and HBcAg were 2.84%,44.05%,0.64%,1.93%,33.44%respectively in 20 year age group,while they were 5.69%,65.85%,0.81%,4.07%,69.44%respectively in 80 year age group.The positive rates of anti-HBs,HBeAg,anti-HBe and HBcAg increased with age(x2trend=256.16,P＜0.001).Among 3744 objects,530 subjects (accounted for 14.16%)had the family history of hepatitis B.HB immunization coverage rate was 11.77% (393/3339),with the standardized rate being 20.20%.The positive conversion rate of anti-HBs among those had HB vaccine inoculation was 21.12%(83/393).Conclusion The infection rate of HBV was high,whereas the immunization rate of hepatitis B vaccine and the level of anti-HBs were low in adults,Thus,to improve the immunization rate of hepatitis B vaccine is a key step to decrease the infection rate.

Objecgive To investigate the HB awareness,the infection rate of HBV and the immunity status among adults at the communities of Wuxi,and to provide some evidences for vaccination strategy.Methods Two communities were enrolled in the study through cluster sampling method.A household survey was conducted to collect subjects' information through a face-to-face interview and blood samples were collected to detect HBsAg,anti-HBs,HBeAg,anti-HBe and anti-HBc.Results 3744 subjects were enrolled in this study.The general knowledge coverage rate of hepatitis B was high and 87.30%respondents claimed that hepatitis B was an infectious disease.The percentage of subjects who got more than 5 scores in persons had got hepatitis B vaccination was 60.18%(239/393),and this was significantly higher than in those without vaccine inoculation(x2=17.07,P＜0.01),with the proportion being 49.49%(1071/2164).rnIe percentage of subjects who got more than 5 scores in persons had family history of HBV infection was 60.00%(318/530),and this wag significantly higher than in those without family history (x2=53.05,P＜0.01),with the proportion of 43.00%(1382/3214).The standardized HBV infection rate was 49.88%.There were 1109(29.62%)subjects whose HBsAg,anti-HBs,HBeAg,anti-HBe and HBcAg were negative.There were 8 subjects(0.21%) whose HBsAg,HBeAg and anti-HBc were positive simultaneously,and there were 133 subjects(3.55%)whose HBsAg,anti-HBe and anti-HBc were positive simultaneously.The positive rate of anti-HBc was significantly higher in males than in females( 59.37%and 53.08%,P=0.00).The positive rates of HBsAg,anti-HBs,HBeAg,anti-HBe and HBcAg were 2.84%,44.05%,0.64%,1.93%,33.44%respectively in 20 year age group,while they were 5.69%,65.85%,0.81%,4.07%,69.44%respectively in 80 year age group.The positive rates of anti-HBs,HBeAg,anti-HBe and HBcAg increased with age(x2trend=256.16,P＜0.001).Among 3744 objects,530 subjects (accounted for 14.16%)had the family history of hepatitis B.HB immunization coverage rate was 11.77% (393/3339),with the standardized rate being 20.20%.The positive conversion rate of anti-HBs among those had HB vaccine inoculation was 21.12%(83/393).Conclusion The infection rate of HBV was high,whereas the immunization rate of hepatitis B vaccine and the level of anti-HBs were low in adults,Thus,to improve the immunization rate of hepatitis B vaccine is a key step to decrease the infection rate.