This article reviews the types and development of informatics nurses in the United States, focusing on their qualification certification and employment, analyzes the development status of informatics nurses in China, and puts forward the implications of the development of informatics nurses in the United States to China, aiming to provide reference to the specialization of nursing informatics and nursing talents and provide guarantee for the training and rapid development of informatics nurses, thereby promoting the development of nursing informatics and advancing hospital informatization in China.