Objective To evaluate the effect of malaria control in Shayang County from 1995 to 2014,so as to provide the evidence for the strategy revision of the elimination of malaria prevention and control. Methods The data of malaria surveil?lance were collected and analyzed in Shayang County from 1995 to 2014. Results During the 20 years,582 malaria patients(9 imported patients)were reported. The average annual incidence rate was 0.53/ten thousand. Through the comprehensive preven?tion and control measures,the incidence of malaria decreased from 2.30/ten thousand in 1997 to 0.02/ten thousand in 2010,and the decreasing rate was 99.13% . The proportion of malaria cases in the total infectious diseases cases also decreased from 21.23% in 1997 to 0.07% in 2010,and the decreasing rate was 99.67%. There were no local malaria patients from 2010 to 2014. However,the imported malaria patients were increased year by year during the recent years. Conclusions This county has reached the national malaria control and elimination standards,and the malaria control work has been transferred from the con?trol period to the elimination phase. We should implement the prevention and control measures and strictly control imported ma?laria,so as to consolidate the malaria control results.

AIM:To analyze the correlation between serum angiotensin-converting enzyme 2 (ACE2) levels and different stages of coronary heart disease (CHD), and to explore the change of serum ACE2 level during the development of CHD.METHODS:The control group included 85 non-CHD samples, and 174 CHD samples were divided into light stenosis (ls-CHD, stenosis degree <50%) group, moderate stenosis (ms-CHD, stenosis degree 50%~75%) group and severe stenosis (ss-CHD, stenosis degree ≥75%) group.The ACE2 level in each serum sample was detected by ELISA.The relationship between the ACE2 level and the development of coronary heart disease was explored by statistical analysis of serum ACE2 levels in different stages of CHD.RESULTS:The serum ACE2 levels in ls-CHD group, ms-CHD group and ss-CHD group were all higher than that in control group.The more severe the coronary artery stenosis existed, the higher the ACE2 level was observed.The serum ACE2 level in the males was higher than that in the females.In a single sex, the serum ACE2 levels in ls-CHD group, ms-CHD group and ss-CHD group were higher than that in control group with significant differences.Regression analysis found that sex, diabetes and CHD were associated with the serum ACE2 levels.Among them, sex and CHD were the independent factors to affect serum ACE2 levels.CONCLUSION:The serum ACE2 level of males was higher than that of females.Compared with the non-CHD samples, the serum ACE2 level of CHD patients was higher than that of the non-CHD samples.During the development of coronary heart disease, the serum ACE2 level increased constantly.