1.Research Progress in Animal Models of IBS-D Disease Combined with Liver Stagnation and Spleen Deficiency
Yuanyue SHU ; Xiaoqin XIAO ; Guiming DENG ; Zhen CHEN ; Liping YANG ; Linqi OUYANG ; Yanping HE ; Biao XIANG ; Hai HE
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(6):134-136
At present, TCM treatment of diarrhea-predominant irritable bowel syndrome (IBS-D) is based on the combination of disease differentiation and syndrome differentiation. Therefore, the establishment of IBS-D of liver stagnation and spleen deficiency syndrome combined with animal model as a combination of traditional Chinese and Western medicine innovation theory has become increasingly concerned about, and gradually become a new direction for the development of TCM experimental animal model. This article reviewed the research progress in IBS-D liver and spleen deficiency syndrome in recent years, discussed the establishment of IBS-D liver stagnation and spleen deficiency animal model and research ideas for the treatment of IBS-D, and provided references for mechanism research of TCM treatment for IBS-D and research and development of new medicine.