Sepsis is a major cause of mortality among children and newborns.The largest part of the global pediatric sepsis burden occurs in middle-and low-income countries,where the mortality of sepsis reaches 24％-50％.It is necessary to provide clinicians with a framework to improve the management of pediatric septic patients.The key of treatment is to ensure adequate tissue perfusion,to maintain cardiovascular and hemodynamic stability,the administration of adequate antibiotics,the proper use of glucocorticoid,and so on.

Objective To observe the curative effect of acupuncture point bloodletting,flash tank combined with ultrashort wave auxiliary in the treatment of infantile cough.Methods 102 children with cough were selected and randomly divided into control group (50 cases)and observation group (52 cases).The control group adopted general anti -infection,reduce phlegm,the method of atomizing inhalation.The observation group received control method based on the acupuncture point thorn bloodletting,cans,combined with ultrashort wave.The clinical curative effect was compared in the two groups.Results In the treatment group,34 cases got cure,improvement in 17 cases, 1 case had no effect,the cure rate was 65.3%,total effective rate was 98.0%,without efficiency 1.9%.In the control group,18 cases got cure,improvement in 23 cases,9 cases of invalid,and the cure rate was 36.0%,the total effective rate was 82.0%,without efficiency was 18.0%.The total effective rate between the two groups had statistically significant difference (χ2 =4.105,P <0.05).Conclusion Acupuncture point bloodletting,flash tank combined with ultrashort wave auxiliary in the treatment of infantile cough can obviously improve the clinical effect.

Objective:To investigate the effect of IRH on pulmonary fibrosis and its intervention mechanism.Methods:45 sprague-dawley rats were randomly divided into three groups.The model group and the intervention group were received endotracheal injection of bleomycln to induce pulmonary fibrosis,while the control group were received endotracheal injection of saline.From the second day the intervention group IRH were injected to the stomach,while the other two groups were injected saline instead.On the 7th day,14th day and 28th day the lungs were isolated.The expression of MMP-2 and TIMP-1 was detected by immunohistochemical method respectively.Results:There was only a very weak expression of MMP-2 and TIMP-1 in the control group,there was significantly higher level in model group compared with control group on the 7th day,14th day and 28th day.The IRH group was significantly lower than the model group with the same time points,though it was also obviously higher than the control group all over the period(P

Fractal is a new conception.In this paper some knowledge of fractal is first described.Our research work of fractal application in Doppler ultrasound technique is reported.

Objective To create a sterilized condition in field operation and the daily grind avoiding the intercross contamination between the experimentation and outside. Methods The air in the experimentation was filtrated by primary and advanced filter. High intense ultraviolet was used to sterilize the air, and negative compression was kept in the experiment condition. Results Hyperpurificatory biosafety cabinet guaranteed the sterilization condition in field operation and the daily grind, avoiding the intercross contamination. Conclusion Hyperpurificatory biosafety cabinet can be used in medical treatment, pharmacy, food industry, electrical industry, instrumentation, bioengineering, scientific tests, especially biology species identification in biological warfare.

Objective: To explore the clinical effect of modified preflush on the treatment of CRRT without heparin in patients received dialysis with complication of cerebral hemorrhage. Methods: 44 patients received dialysis with complication of cerebral hemorrhage were divided into control group (28 cases) and observation group (16 cases) according to the implemented time of modified preflush. A retrospective analysis was adopted to compare the effect of filter in blood coagulation grade and service life between conventional preflush (control group)and modified preflush (observation group). Results: The differences of I, II, III grade of blood coagulation between the two methods were significant (x2=12.020, P<0.05), and the differences of average service time of filter, transmembrane pressure(TMP), pressure of filter and value of pressure drawdown (ΔP) between the two methods also were significant (t=3.535, t=4.024, t=6.071, t=3.524, P<0.01). Besides, the difference of venous pressure (PV) between them was significant (t=2.166, P<0.05), while the differences of BFR, UFR and Pa between the two methods were not significant (t=0.263, t=1.162, t=0.258, P>0.05). Conclusion: Modified preflush method can make the fiber of filter to obtain more full stretch and soak, and it also can prolong the service of time, and decrease incidence of blood coagulation, and ensure curative effect and smooth process.

Objective:To explore the effects of formative assessment using sitcom play in obstetrics and gyne-cology nursing teaching.Methods:Totally 214 undergraduate of grade 2011 nursing students were recruited in the present study.Using envelope method,2 classes were randomly selected as the control group and 2 as the experi-mental group.Students in the control group (n--107) were assessed with traditional assessment method,while those in the experimental group (n =107) were taught using situational drama performance and assessed with form-ative assessment method throughout the process.Students' test scores of obstetrics and gynecology nursing in these two groups were compared,and the opinions on the formative assessment method using sitcom play were investiga-ted among students in the experimental group.Results:Students in the experimental groupscored significantly high-er than those of the control group(78.43 ± 5.21 vs.76.67 ± 6.40,t =2.20,P ＜ 0.05).About 98.31％ of the students approved the formative assessment mode.They reported that this approach was helpful to improve the abili-ty to combine theory and practice andto communicate with others,to cultivate students' creative thinking,and to stimulate their learning interest and learning initiative.Conclusion:The application of formative assessment mode using sitcom play in obstetrics and gynecology nursing teaching is beneficial to enhance teaching effect and improve the ability of nursing students,which is worth popularizing.

ObjectivesTo study the clinical characteristics, the risk factors and outcomes of arterial ischemic stroke (AIS) and hemorrhagic stroke (HS) in children.MethodsThe clinical data from 142 children with AIS or HS were retrospectively re-viewed and compared from Nov. 2010 to May 2014.ResultsIn these children, 92 cases (64.8%) was diagnosed of AIS, amont whom there were 60 males and 32 females and the onset age of stroke was 4.6±3.6 years (1 months to 16 years old), and 50 cases (35.2%) was diagnosed of HS, among whom there were 34 males and 16 females and the onset age of stroke was 2.6±3.7 years (1 months to 13 years old). The difference in age between two groups was statistically signiifcant (P=0.007). The most common presentation of AIS were focal neurological dysfunction including paralysis (73 cases, 79.3%), central facial palsy (30 cases, 32.6%) and speech impairment (19 cases, 20.7%). The most common presentation of HS were diffuse neurological dysfunction including dizziness (29 cases, 58.0%), nausea/vomiting (22 cases, 44.0%) and headache (14 cases, 28.0%). The major risk factors of AIS were arteriopathy (49 cases, 53.3%), infection (47 cases, 51.1%) and minor head injury (16 cases, 17.4%). The major risk factors of HS were vitamin K deifciency (22 cases, 44.0%), intracranial vascular anomalies (8 cases, 16.0%) and haematological disorders (6 cases, 12.0%). Five cases (6.4%) were died, 48 cases (61.5%) became disabled and 9 cases (11.5%) were relapsed in children with AIS while 15 cases (34.1%) were died, 19 cases (43.2%) became disabled in children with HS. The mortality was signiifcantly higher in children with HS than that in children with AIS (P<0.01).ConclusionsIn childhood stroke, HS occurs more frequently than is commonly appreciated and it has a poorer prognosis than AIS.

Objective To explore the application of partial least square regression model in the study of personality characteristics of the scientific personne1,to supply more reliable and scientific rationale to the training and intelligent use of scientific personne1 in colleges.Methods We took our survey by 114 scientific personnel from eight universities with NEO-PI-R(Revised NEO Personality Inventory).After the process of simplifying the NEO-PI-R,we need partial least square regression model to analyze.Results The results of the PLS analysis indicates the goodness-of-fit of the model was good,which opened out clearly and intuitively the connection between the items and five personality characteristics,the model could be used as theory reference for personnel department,research department and education department to consummate the training of scientific personne1 in colleges.Conclusion Partial least square regression model could be used to study personality characteristics of the scientific personne1 in colleges as statistic method appearing recently.

High-frequency ventilation ( HFV) is theoretically an ideal ventilatory mode for lung pro-tection. It also delivers extremely small tidal volumes near to or less than the anatomically invalid cavity (about 2ml/kg) at very high respiratory frequencies (recognized ventilation frequency about 4 times more than the normal range) . Compared to the conventional mechanical ventilation,HFV makes use of lung-open mode,with low tidal volume, low airway pressure, low thoracic pressure and end-exhaling pressure effect, which can avoid recruitment/derecruitment of alveoli to reduce pressure injuries on lung tissue and airway. Nowadays,more and more critical care practitioners implement this ventilation mode. We reviewed the princi-ples,classification,parameters,and clinical indications of HFV in this article.