Among 941 patients of AMI admitted in the period from Jan 1969 to Jan 1989, 89 cases were complicated with diabetes mellitus (9.5%). The diabetic patients are older than non-diabetic, the occurrence of reinfarction and complications during AMI were more frequent and the mortality was higher incidence of complication of hypertension (69.7%) and hyperlipi-demia(39.3%).The clinical characteristics of AMI in diabetic patients are: higher occurrence of silent myo-cardial infarction and more frequent occurrence of heart failure. Recently, evidences from clinic-pathologic and epidemiologic investigations and experimental studies suggest that diabetes mellitus is associated not only with severe coronary atherosclerosis, but also microangiopathy, disorders in vegetative nervous system, and pathology of the myocardium. Therefore effective measures for prevention and treatment of diabetes is very important to decrease the mortality of AMI.

Objective:To investigate genetic characteristics of human rhinovirus (HRV) in adult inpatients with pneumonia in autumn and winter in Bengbu, Anhui province, 2021.Methods:The pharyngeal swabs of inpatients with pneumonia in Bengbu were collected for the detection of 14 common respiratory pathogens by Real-time PCR during September to December 2021. VP4/VP2 coding regions of HRV positive samples were amplified by nested PCR and phylogenetic tree was constructed using MEGA7.0.Results:A total of 146 samples were collected from inpatients with pneumonia; 35.62% (52/146) samples were positive with at least one pathogen. The four viruses with high detection rate were HRV, adenovirus, human coronavirus OC43 and influenza B virus. HRV positive samples accounted for 44.23% (23/52) of the positive samples, among which 9 cases (39.13%, 9/23) co-infected with HRV. Phylogenetic analysis found that HRV infection were dominated by HRV-A and HRV-B groups. The analysis based on clinical syndrome found that the white blood cells count and the proportion neutrophils of patients with HRV co-infection were higher that of HRV single infection. The proportion of patients with hypertension, diabetes, mechanical ventilation and poor prognosis in the HRV co-infection group were higher than that of HRV single infection group ( P<0.05). Conclusions:HRV is the predominant pathogen among the adult inpatients with pneumonia in Bengbu. HRV-A and HRV-B groups are common. Patients accompanied by hypertension, diabetes were easily co-infected with HRV. Patients coinfeted with HRV are more likely to be mechanical ventilation and poor prognosis.