Objective To discuss clinical efficacy of shuxuetong in treatment of pulmonary fibrosis. Methods Selected 60 cases with pulmonary fibrosis and they were divided into control group of 30 cases treated by prednisone and study group of 30 cases treated by shuxuetong based on treatment of prednisone. Lung function, arterial blood gas and lung CT were compared. Results The efficiency of study group was higher than control group (P<0.01). FEV1 of study group after treatment was higher than before treatment, and was higher than control group after treatment(P all<0.05). PaO2 of study group after treatment improved apparently, and was higher than control group (P<0.05). Conclusion Clinical effi-cacy and lung function of mild, moderate pulmonary fibrosis patients are improved with treatment of shuxuetong based on prednisone.

Objective To discuss serum IL-13, TGF-β1, IL-8 levels in idiopathic pulmonary fibrosis and correlation with lung function. Methods A total of 60 cases with idiopathic pulmonary fibrosis were selected as pulmonary fibrosis group, and 60 healthy volunteers were selected as control group. Serum IL-13, TGF-β1, IL-8, arterial blood gas analy-sis and related indicators of lung function were detected. Results Serum IL-13, TGF-β1, IL-8 levels of idiopathic pul-monary fibrosis group were higher than the control group(P<0.01). TGF-β1, IL-8 were significantly negative correlation with FVC predicted percentage (P<0.01); TGF-β1, IL-13 were significantly negative correlation with FEV1 predicted percentage (P<0.01); TGF-β1 and PaO2 was significantly negative correlation, and TGF-β1, IL-8 were significantly positive correlation with P(A-a)O2 (P<0.01);IL-8 was significantly negative correlation with PaO2 and SaO2 (P<0.01). Conclusion Serum IL-13, TGF-β1, IL-8 levels in idiopathic pulmonary fibrosis increase significantly, and are nega-tive correlation with lung function.