1.Application of artificial pneumothorax combined with intercostal nerve block in alleviating chest pain during percutaneous microwave ablation for subpleural lung malignancy: analysis of therapeutic efficacy
Xiaowei HOU ; Xingjun ZHUANG ; Haiwen ZHANG ; Kai WANG ; Yuanxin ZHANG
Journal of Interventional Radiology 2017;26(3):269-273
Objective To discuss the clinical effect of artificial pneumothorax combined with intercostal nerve block in alleviating chest pain occurring during and after percutaneous microwave ablation (MWA) for subpleural lung malignancy.Methods A total of 30 patients with subpleural lung malignancy were randomly and equally divided into group A (n=10),group B (n=10) and group C (n=10).The patients in group A received both artificial pneumothorax and intercostal nerve block before MWA.The patients in group B only received artificial pneumothorax before MWA,and the patients in group C only received intercostal nerve block before MWA.The degree of pain was evaluated by visual analogue scale (VAS) score during MWA,immediately after MWA and at 6 h,12 h and 24 h after WMA.The side effects after MWA were recorded.Results During MWA,no statistically significant differences in VAS scores existed between each other among the three groups (P=0.885).The VAS scores determined at 6 h,12 h and 24 h after MWA in group C were significantly increased (P=0.014,P=0.006 and P=0.006 respectively).No patient in group A and group B developed symptoms of chest tightness after artificial pneumothorax was performed.After treatment,a small amount of asymptomatic residual pneumothorax was still observed in 6 patients of group A and group B,which disappeared spontaneously in about one week.Another patient still showed massive pneumothorax even after thoracic gas suction,and the patient recovered after thoracic closed drainage for three days.No other serious complications related to artificial pneumothorax occurred.Conclusion Artificial pneumothorax combined with intercostal nerve block can effectively relieve the chest pain occurring during and after MWA in patients with subpleural lung malignancy,and clinically this technique is quite safe.(J Intervent Radiol,2017,26:269-273)
2.Role of scapholunate interosseous ligament in flexion-extension motion of scaphoid and lunate
Xiuzhong LI ; Jinfang CAI ; Yuanxin ZHANG ; Xu LIU ; Haiping TANG ; Shujian HOU ; Shizhen ZHONG
Chinese Journal of Trauma 2011;27(10):919-923
Objective To observe the resection of the scapholunate interosseous ligament (SLIL)and its subregions on the three-dimensional(3-D)movement of the scaphoid and lunate so as to discuss the role of SLIL in the 3D flexion-extension motion of the scaphoid and lunate.Methods Twelve upper extremities(six left extremities and six right extremities)from adult cadaver were used in this study and divided into five groups:normal group,proximal subregion resection group,proximal subregion plus dorsal subregion resection group,proximal subregion plus palmar subregion resection group and whole SLIL resection group.The 3-D laser scan and reconstruction technique were used for meusure ment of the 3-D flexion-extension motion of the scaphoid and lunate.Results In the normal group,the scaphoid and lunate flexed and the radial deviated at the same direction during wrist flexion-extension motion.At the same time,there was minimal scaphoid and lunate pronation-supination during wrist flexionextension.After resection of the proximal and palmar(or dorsal)subregions of the SLIL,some different movements were found compared with the normal specimen.Whole SLIL resection resulted in increase of the flexion motion of the scaphoid but decrease of the palmar flexion of the lunate.Conclusions 3-D laser scanning and image reconstruction techniques can accurately measure the 3D motion of the scaphoid and lunate.Partial or whole resection of SLIL may exert significant effect on the flexion-extension motion of the scaphoid and lunate.However,the proximal subregion of SLIL has no prominent effect on the motion of the scaphoid and lunate.
3.Study on Chemical Constituents of Petroleum Ether Part from Whole Herbs of Pteris vittata
Yuanxin HOU ; Shufen HOU ; Rongmin GAO ; Jiayi CHEN ; Wenyue XING ; Xing TU
China Pharmacy 2019;30(6):817-820
OBJECTIVE: To study the chemical constituents from the petroleum ether part from whole herbs of Pteris vittata. METHODS: The petroleum ether part from whole herbs of P. vittata was separated and isolated by silica gel column, gel column, recrystallization and TLC. The structures of the compounds were identified according to physicochemical properties and spectrum data (1H-NMR and 13C-NMR). RESULTS: A total of 11 compounds were isolated and identified from the petroleum ether part from whole herbs of P. vittata, as (2R)-acetyl pterosin B (Ⅰ), palmitic acid (Ⅱ), hop-22(29)-ene (Ⅲ), epifriedelanol (Ⅳ), lupenone (Ⅴ), olean-18-en-3-one (Ⅵ), stigmasterol (Ⅶ), β-sitosterol (Ⅷ), 22-hydroxyhopane (Ⅸ), ergosterol (Ⅹ), β-sitosterol acetate (Ⅺ). CONCLUSIONS: Compounds Ⅰ-Ⅶ and Ⅸ-Ⅺ are isolated from this plant for the first time, and can provide theoretic reference for further studying bioactive pharmacodynamic substances in P. vittata and enriching chemical component data.