Purpose To confirm the effects of acupuncture, and Chinese medicines in controlling the withdrawal symptoms from the opium-like drugs. Method 96 heroin-dependent subjects were divided into four groups,which were treated respectively by western medicine (Agroup), acupuncture (B group), Chinese herbs (Cgroup), and acupuncture & Chinese herbs (D group).Before, during and after treatment, the concentration of serum testosterone and prolactin, and immune functions (serum CD3+ 、CD4+ 、CD8+ and CD4+/CD8+ ) were tested.Results After treatment, the concentration of serum testosterone in A and B group were higher than before and during treatment, and in C and D group, during treatment were higher. In the four groups, the concentration of serum prolactin before treatment was the highest. The levels of CD3+、CD4+、 CD8+ and CD4+/CD8+ were lowest before treatment and highest after treatment. Conclusion Acupuncture and Chinese medicines effective in relieving spasm and pain can control the opium-like drug withdrawal symptoms to different degrees, especially acupuncture. However, acupuncture cannot ease the withdrawal symptoms completely. Acupuncture does not strikingly cooperate with the Chinese medicines effective in relieving spasm and pain (including M-receptor antagonists). In detoxification, the Jiaji points are the primary ones and symptom-based points the secondary ones.

Objective To study the effect of TCM five-tone therapy on chronic fatigue syndrome(CFS).Methods Fifty nine CFS patients were divided into the treatment group(n=30)and the control group(n=29),which received TCM five-tone therapy and common music therapy,respectively for 3 months.Both groups were assessed with fatigue Scale-14,depression status inventory and visual analogue scale.Result After treatment,the treatment group was scored lower than the control group in FS-14,DSI and VAS(all P<0.05).Conclusion TCM five-tone therapy may be more effective in decreasing the CFS patients with fatigue and depression and alleviating their pain symptoms.

Objective To analyze the law of medicinals and discuss rules of clinical administration of Chinese medicinals and features of pattern differentiation and treatment in treatment of diabetic macular e -dema(DME).Methods The literature using TCM decoctions for treating DEM published at home and abroad were collected, analyzed and studied by applying modern computer data mining technology The core medicinals,core couplet medicinals and core medicinal combinations were analyzed,and the presic-riptvons law was explored.Results A total of 54 articles were included in this study involving 99 kinds of medicinals with a total frequency of 540 counts.The top ten frequent single medicinals were Fuling (Indian Bread, Poria), Zexie(Oriental Waterplantain Rhizome, Rhizoma Alismatis), Huangqi (Milkvetch Root,Radix Astragali seu Hedysari), Danggui(Chinese Angelica, Radix Angelicae Sinen-sis),Chuanxiong(Sichuan Lovage Rhizome,Rhizoma Ligustici Chuanxiong), Zhuling(Chuling,Pol-yporus),Shengdihuang(Unprocessed Rehmannia Root,Radix Rehmanniae Recens),Baizhu(White At-ractylodes Rhizome,Rhizoma Atractylodis Macrocephalae),Danshen(Salvia Root,Radix Salviae Miltior-rhizae), and Cheqianzi(Plantain Seed, Semen Plantaginis).There were 19 types of TCM patterns, which were divided into 3 categories: phlegm-stasis obstruction, spleen deficiency and water retention, and qi-blood and yin-yang deficiency.The top four couplet medicinals according to association rules were Fuling-Huangqi,Fuling-Zexie,Chuanxiong-Danggui,Fuling-Danggui.The top three-medicinal combi-nations according to association rules were Fuling-Chuanxiong-Danggui, Zexie-Danggui-Fuling, and Fuling-Zexie-Huangqi.The top three four-medicinal combinations according to association rules were Zexie-Chuanxiong-Danggui-Fuling, Chuanxiong-Danggui+Huangqi+Fuling, and Zexie-Danggui-Huan-gqi-Fuling.Conclusion DME was treated mainly with medicinals with effects of tonifying qi and indu-cing dieresis,and with medicinals with effects of activating blood and enriching blood to supplement.The TCM pathogenesis of DME is qi-blood and yin-yang deficiency leading to internal water retention,binding of phlegm-stasis and obstruction of ocular collaterals over the time.

At present, the registration process of Traditional Chinese Medicine (TCM) in Canada is refering to the requirements of Natural Health Products (NHPs). In terms of registration material, both NHPs and TCM include plants, animals and minerals with medicinal components, but the fundamental difference between them is that TCM is guided by the basic theory of TCM. As for the registration classification of TCM in Canada, first of all, judge whether the product to be applied for is NHPs; Secondly, we should clarify the types and ways of registration, mainly including simple application, traditional application and non-traditional application, and provide application forms, label texts, summary reports, evidence, animal tissue forms, finished product specifications and other materials according to different requirements. At present, the successful registration experience of TCM products in Canada mainly mainly includes applying for superior varieties, selecting appropriate application channels, communicating with local health management units and providing sufficient scientific evidence and good clinical application records. The regulations on the registration of NHPs in Canada have not fully considered the particularity of TCM and the registration of TCM products is still facing some difficulties. In the future, we can learn from the registration process and requirements of the Health Canada, promote the interconnection and mutual recognition of the Pharmacopoeia of the People's Republic of China and the NNHPD monographs in Canada, reduce the obstacles to the local application for registration of TCM, and promote the further improvement of the international standards of TCM.

Traditional Chinese Medicine (TCM) products could be registered as natural health products (NHPs) in Canada. Its registration process could be mainly divided into simple-application, traditional-application and non-traditional application. By analyzingi the TCM registration evidence system and its safety, effectiveness and quality required by different registration categories in Canada, we found that "simple-application" procesure needs to submit evidence based on the parameters of a component in the monograph. As for "traditional application", TCM products need to be used at least 50 years with, traditional material or Pharmacopoeia can be used as evidence; As for non-traditional application, TCM products need to provide evidence according to the disease risk level, and most of them need to provide scientific experiment evidence. Therefore, from the experience of TCM registration evidence system in Canada, the registration of TCM products should pay attention to improve the its classification method, refining its evidence requirements and data types, promoting the formulation of monograph of TCM, realizing the scientific evaluation and rapid review of classic famous prescriptions, and promoting the inheritance and innovative development of TCM in China.

Humans ; Severe Acute Respiratory Syndrome ; diagnosis ; therapy