Purpose:Investigate the clinical value of tumor markers CEA, CA50, CA199 and CA242 for the diagnosis of lung cancer.Methods:The 223 serum sample included 41 cases of squamous cell carcinoma, 46 cases of adenocarcinoma, 14 cases of small cell lung cancer, 16 cases of unclassified carcinoma, 6 cases of metastatic carcinoma, 100 cases of benign lung disease. The levels of CEA, CA50, CA199 and CA242 in the plasm were measured by ELISA. Some data were analyzed by t and ? 2 test. The results were analyzed with regard to sensitivity, specificity, negative prognostic value, positive prognostic value and positive percentage.Results:In all malignant groups the value of CEA was higher than normal value,while in benign group. There was notable difference (P

Idiopathic pulmonary fibrosis (IPF) is characterized by diffuse alveolitis and disorder of alveolar structure and eventually leads to pulmonary interstitial fibrosis. The cause of IPF is unknown and there is no effective treatment for IPF. There is no effective treatment for IPF, mainly to delay disease progression and improve patient's quality of life. At present, the incidence of IPF with lung cancer (IPF-LC) has increased significantly, which resulted in higher mortality and reduced quality of life. IPF-LC is more common in men, elderly, and smokers. It is a fatal disease and its clinical manifestations lack specificity. IPF-LC has no clear treatment plan, meanwhile, the median survival time is short, and the prognosis is poor. At present, the pathogenesis and treatment plan of IPF-LC are not clear. This article provides a brief review of the current research on the risk factors, pathogenesis, clinical characteristics and treatment of IPF-LC.