Objective To study the effect of finasteride on preventing prostate hyperplasia with acute urinary retention.Methods Totally 626 patients with benign prostatic hyperplasia (BPH) were randomly divided into treatment group (316 cases) and control group (310 cases),followed up for 3 years.The incidence of acute urinary retention and prostate volume changes were analyzed.Results There were 3 cases of acute urinary retention in treatment group (1.0 ％),9 cases in control group (2.9％) (x2 ＝5.37,P＜0.05).In treatment group,the average prostate volume was reduced about 23.6％ compared with before taking the medicine,on the contrary,prostate volume was averagely increased 12.3％ in control group.Conclusions Finasteride can reduce the risk of acute urinary retention by narrowing the prostate volume in patients of benign prostatic hyperplasia.

ObjectiveTo study the feasibility,safety and efficacy of laparoscopic cyst excision and Roux-en-Y hepaticojejunostomy for adult congenital choledochal cyst.MethodA retrospective study was conducted on 7 adult patients with congenital choledochal cyst who received total laparoscopic cyst excision and Roux-en-y hepaticojejunostomy from May 2008 to February 2011 in the Department of General Surgery of Shengjing Hospital,China Medical University.ResultsAll the laparoscopic surgery was successful.The mean operation time was 210 minutes.The average intraoperative blood loss was 80 ml.All patients were out of bed within the first 24 h after surgery.The mean time to first flatus/bowel motion was 2.4 days.Except 1 patient who had small amount of bile leakage,all patients recovered smoothly without any major postoperative complications.The average hospital stay was 8.1 days.No patients suffered from abdominal pain,fever or jaundice during follow-up from 3 to 30 months.ConclusionTotal laparoscopic cyst excision and Roux-en-Y hepaticojejunostomy was a safe,efficacious,and minimally invasive procedure.

0. 05). Conclusion The expression of VEGF is highly related to the invasion, DNA ploidy and cellular proliferation activity of malignant bone tumor. It isn't related to the size of tumor. The expression of VEGF is probablya predictor for judgment of malignant degree of bone tumor.

Objective To Study the criteria of assessment on the degree of mental damage due to in-jury. Methods A retrospective study of 297 mental damage cases caused by injury expertised by the depart-ment of legal psychiatry of Tongji Medical College, Huazhong University of Science and Technology from July 1986 to December 2002 was conducted. Results In 297 cases, 91 were heavily injury, 93 were moder-ate. 44 cases were slight injury, and 69 cases between injury and disease. Conclusion The Study proposed a concrete and practical assessment criteria of forensic expertise of mental damage by the analysis of these 297 cases. We hope this criteria is developed into perfection in future forensic expertise.

OBJECTIVETo observe clinical therapeutic effect of fuzhong (supporting the middle-jiao) manipulation of tuina for infantile anorexia.

METHODSEighty-one children with anorexia were treated with fuzhong manipulation, including abdominal kneading, acupressure at Zhongwan (CV 12), Lanmen (Extra), Tianshu (ST 25), Zusanli (ST 36), Sanyinjiao (SP 6), spine pinching, warm moxibustion and warm scraping with supporting-yang cupping, three times a week, six times as a session. Onset time, therapeutic effect and TCM symptom scores before and after treatment were observed after two sessions and differences of therapeutic effect among different patterns were compared.

RESULTSSeventy-two children had the effect in one session while 41 children had the effect within half of a session. 38 cases were clinically cured, 15 cases were markedly effective, 23 cases were effective and 5 cases were failed. The total effective rate was 93.8%. Compared with before treatment, TCM symptom scores, including appetite, food intake, complexion and defecation, were all obviously improved after treatment (all P < 0.001). The clinical cured rate was 45.2% (19/42) in the pattern of dysfunction of spleen in transportation, 45.8% (11/24) in the pattern of qi deficiency of spleen and stomach, 50.0% (4/8) in the pattern of yin deficiency of spleen and stomach, 57.1% (4/7) in the pattern of liver sufficiency and spleen insufficiency, which had no obvious differences among different patterns (all P > 0.05).

CONCLUSIONThe fuzhong manipulation of tuina has quick onset time and satisfied clinical therapeutic effect, which could obviously improve symptoms and is fit for different patterns of infantile anorexia.

Adolescent ; Anorexia ; physiopathology ; therapy ; Child ; Child, Preschool ; Eating ; Female ; Humans ; Infant ; Male ; Massage ; Meridians ; Spleen ; physiopathology ; Stomach ; physiopathology ; Yin Deficiency ; physiopathology ; therapy

Acupuncture Therapy ; methods ; Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Needles ; Tourette Syndrome ; therapy

Objective To explore the effect of brain derived neurtrophic factor(BDNF) gene modified umbilical cord mesenchymal stem cells ( UCMSC ) transplantation on neurological functional improvement in rats after brain trauma.Methods Cerebral contusion model in motor-sensory cortex in rats was established by a weight hammer falling method.UCMSC were cultured and transferred with BDNF gene.After BDNF expression and activity were determined,the BDNF gene modified UCMSC were implanted into traumatic brain.The neurological function was evaluated for 2 weeks after brain injury.And the BDNF expression was determined by using immunohistochemistry.Results Severe neurological dysfunction was seen in animals that had been subjected to contusion brain injury( 10.50 ±0.53 ).A significant improvement on neurological function was found in the UCMSC transplantaion animal( 7.75 ± 0.71 ), compared with only brain injury group (P ＜ 0.01 ).Moreover, rats in BDNF gene modified UCMSC showed the most behavior improvement ( 5.50 ± 0.76 ) (P ＜ 0.01 ).Conclusion BDNF gene modified UCMSC transplantation can survive and migrate, and improve neurological function in brain traumatic rats.

Objective To investigate the effect of NGF gene modified umbilical cord mesenchymal stem cells (UCMSC) transplantation on neurological functional improvement in traumatic brain rats. Methods Cerebral contusion model in motor-sensory cortex in rats was established by a weight hammer falling method. UCMSC were culutred and transferred with NGF gene. After NGF expression and activity was identified,the NGF gene modified UCMSC were engrafted into injured brain. The neurological function was evaluated 2 weeks after brain injury. And the NGF immunostaining was also performed to explore the level of NGF expression. Results Severe neurological dysfunction( 10.50 ± 0.53 )occurred in rats after traumatic brain injury, while the UCMSC transplantaion led to a significant functional improvement( 7.75 ± 0. 71 )(P ＜ 0. 01 ). Moreover, the best functional improvement was found in rats receiveing UCMSC grafts modified with NGF gene (5.38 ± 0. 52 ) (P ＜ 0.01 ). Conclusion NGF gene modified UCMSC transplantation can improve neural behavior in rats with brain trauma.

Objective To optimize the purification technology of total flavonoids from the Tripterospermi Chinensis Herba by macroporous resin. Methods The purification abilities of six kinds of macroporous adsorption resins for total flavonoids from Tripterospermi Chinensis Herba were studied with the adsorption and desorption rates as the index by static adsorption and desorption experiments. The column liquid concentration, adsorption rate, and the loaded amount were studied by using dynamic adsorption experiments. The optimal desorption technology was examined by orthogonal experiment. Results AB-8 macroporous resin was found to have good adsorption and desorption effects. The optimal purification conditions were as follows:the column liquid concentration was 5.285 mg/mL, adsorption rate was 2 BV/h;the loaded amount was 17.62 mg/mL. The sample was eluted by 10%ethanol with 4 BV and 50%ethanol of 5 BV at a flow rate of 4 BV/h. The purity of total flavonoids increased to 61.95% after the purification, and the yield was 87.28%. Conclusion This optimized process was stable, feasible and suitable for separation and purification of total flavonoids from Tripterospermi Chinensis Herba.

Objective To explore the method and effects of operative treatment of superior shoul-der suspensory complex(SSSC)injury.Methods A total of 18 patients with SSSC injury were enrolled. There were six cases of scapular neck fracture combined with comminuted clavicle fracture,five cases of scapular neck fracture combined with acromial fracture,and two cases of comminuted clavicle fracture com-bined with acromial and glenoid fracture.These patients were treated with open reduction and internal fixa-tion.Three patients had acromioclavicular joint dislocation combined with coracoclavicular ligament rupture and they were given hook plate fixation and ligament repair.One patient with scapular neck fracture com-bined with acromioclavicular joint dislocation,and one patient with comminuted clavicle fracture combined with coracoclavicular ligament rupture,were treated with the open reduction,internal fixation and the liga-ment repair.Results All patients were followed up for 3 to 14 months,with an average of 9 months.Ana-tomical reduction and healing were all achieved within 7 to 12 weeks,with an average of 8.6 weeks.Con-clusion Anatomical structure of SSSC is very complex and surgery is given priority to internal fixation, which restores the stability good therapeutic effect.