1.The application of endoscopic sinus joint laryngoscope in laryngeal microsurgery
Yang XIAO ; Yi YUAN ; Jinglian CHEN
Chinese Journal of Primary Medicine and Pharmacy 2013;20(4):536-537
Objective To observe the effect applicated of endoscopic sinus joint laryngoscope in laryngeal microsurgery.Methods 68 patients with laryngeal lesions were randomly divided into the multi-mirror combination group (34 cases) and the single laryngoscope group (34 cases).The multi-mirror combination group was taken with laryngeal microsurgery under endoscopic Joint laryngoscope.The single laryngoscope group was only taken with laryngeal microsurgery under laryngoscope.The efficacy and surgical situation of the two groups were compared.Results The total effective rate of the multi-mirror combination group was 97.06%,which was significantly higher than that of the single-laryngoscope group (85.30%) (x2 =4.031,P < 0.05).Compared with the case of surgery and complications and recurrence rate,the multi-mirror combination group was superior to the single laryngoscope group (all P < 0.05).Conclusion The endoscopic joint laryngoscope has the function of expanding the scope of the operative field and increasing the focus and clarity,and also has the advantages of small traumatic for patients,fewer complications,low recurrence rate,easy operation and high accuracy.
2.The significance of TFPI test in Pre-DIC state of rats
Zhong YUAN ; Xichun XIAO ; Min YANG
Journal of Chinese Physician 2008;10(4):487-488
Objective This pre-DIC rat models were constructed by injecting LPS in order to reveal the relationship and significance among tissue factor pathway inhibitor (TFPI),platelet, fibrinogen, prothrombin time and activated partial thromboplastin time. Methods Enzyme-labeled immunosorbent assay was used to detect blood plasma TFPI in pre-DIC state rats(n=16),DIC state rats(n=8)and health rats(n=8).Platelet, fibrinogen, prothrombin time and activated partial thromboplastin time in the same rat were detected. Results TFPI increased first(pre-DIC state)and then decreased(DIC state)in the blood plasma of rata, but the levels of TFPI were always higher than that in the normal state. Conclusions TFPI is more sensitive and accurate to monitor the pro-DIC state than routine examination, which is very useful in the early diagnosis of pre-DIC state.
3.Quality standard of Xinfang Biyan Capsule
Xiao YANG ; Shuiping YANG ; Ling YUAN ; Lin LIU
Chinese Traditional Patent Medicine 1992;0(09):-
AIM: To establish a standard for quality control of Xinfang Biyan Capsule(Radix Saponikovae, Radix Angelicae Dahuricae, Radix Scutellariae, etc.). METHODS: TLC and HPLC were used. RESULTS: Flos Magnoliae, Radix Saponikovae, Flos Chrysanthemi, Radix Bupleuri in the capsule could be identified by TLC, and baicalin content in the capsule could be measured by RP-HPLC with a linear relatioship at a range of 0.243 ?g- 2.43 ?g(r= 0.999 8 ). The average recovery was 98.15% and RSD was 0.15% . CONCLUSION: The methods are accurate and can be used for the quality control of Xinfang Biyan Capsules.
4.Study on HPLC Fingerprint of Total Flavonoids from Pollen ofBrassica campestrisL.
Chengcheng FENG ; Sude YANG ; Shaowei YUAN ; Zhenzhong WANG ; Yuan BI ; Siyang FAN ; Yifang YANG ; Wei XIAO
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;17(3):591-595
In this article, HPLC fingerprint analysis method for total flavonoids from pollen of Brassica campestris L.was established., The HPLC fingerprint was performed on Waters C18 column (250 mm × 4.6 mm, 5 μm), eluted gradiently with the mixture of acetonitrile and 0.4% phosphoric acid aqueous solution at a flow rate of 0.8 mL·min-1. The column temperature was 40℃. The detection wavelength was 320 nm. The HPLC standard fingerprint of total flavonoids from pollen of Brassica campestrisL. was established, and 16 common peaks were calibrated. The method was simple, stable, and reproducible. It could be applied for quality control of total flavonoids from pollen of Brassica campestris L.
5.Pseudocyst of spleen with widespread calcification: report of a case.
Xiao-lu YUAN ; Yi-fei DAI ; Ji-zhou YANG
Chinese Journal of Pathology 2011;40(11):782-782
Adult
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Calcinosis
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diagnostic imaging
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pathology
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surgery
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Cysts
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diagnostic imaging
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pathology
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surgery
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Diagnosis, Differential
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Female
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Humans
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Lymphatic Vessel Tumors
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pathology
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Mucocele
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pathology
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Parasitic Diseases
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pathology
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Spleen
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diagnostic imaging
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Splenectomy
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Splenic Diseases
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diagnostic imaging
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pathology
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surgery
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Tomography, X-Ray Computed
6.Behavior Characteristics in Children with Benign Epilepsy Combined with Centro-Temporal Spikes
yu-han, XIAO ; si-yuan, YANG ; hui-ci, LIANG
Journal of Applied Clinical Pediatrics 2004;0(12):-
Objective To explore the behavior characteristics in children with benign epilepsy combined with centro-temporal spikes(BECTS).Methods Eighty-two children with BECTS aged 2.5-3.0(2.65?2.31)years old,51 male,31 female,who were free of mental retardation assessed with Gesell developmental schedules,untreated with antiepileptic drugs,and were investigated 15 days after the latest seizure.Eighty-two healthy children with sex and age matched to the cases,53 male,29 female,aged 2.5-3.0(2.6?0.4)years old.The behavior characteristics of infants in BECTS group and control group were assessed with CBCL,including 6 behavior factors which were sleep problem,social flinches,depression,physical aspect,attacking,act of sabotage and the infants-middle school student social ability scale.Results The total scores of behavior characteristics and the scores of depression,sleep problem,attacking and act of sabotage in BECTS group were all higher than those in control group,the differences were statistically significant.However,scores of social flinches,and physical aspect in BECTS group had no significant differences compared with those of control group.There were no significant difference of social adaptive component between the BECTS and control group.Conclusions Children with BECTS have behavior disorders to some extent,but their social adaptive capacity are the same as normal children.
7.Robot-assisted laparoscopic radical prostatectomy for prostate cancer: report of 34 cases.
Yan-Zhu WANG ; Xiao-Jian YANG ; Jian-Lin YUAN
National Journal of Andrology 2014;20(9):808-811
OBJECTIVETo assess the feasibility and safety of robot-assisted laparoscopic radical prostatectomy (RLRP) in the treatment of prostate cancer.
METHODSUsing the da Vinci robot surgical system, we performed RLRP for 34 patients with localized prostate cancer and analyzed the intraoperative and follow-up data.
RESULTSThe procedures were performed successfully in all the patients, with the mean operation time of 198 min (range 135-340 min), average blood loss of 257 ml (range 50-700 ml), and 1 case of blood transfusion, but no postoperative complications. Three cases had positive surgical margins. Postoperative examination at 4 weeks showed PSA > 0.2 microg/L in 2 cases, suggestive of residual tumor, for which maximal androgen block therapy was administered. The other 32 patients were followed up for 3-10 (mean 7.5) months, during which the average level of serum tPSA remained < 0.2 microg/L. Urinary continence was found in 94% (32/34) and 97% (33/34) of the patients at 3 and 6 months, respectively, of whom 77% (26/34) and 88% (30/34) had no urinary leakage (0 pad per day).
CONCLUSIONRLRP, with its advantages of less perioperative blood loss, low rate of positive margin, and good urinary continence, is a safe and effective surgical option for the treatment of prostate cancer.
Aged ; Humans ; Laparoscopy ; methods ; Male ; Middle Aged ; Prostatectomy ; methods ; Prostatic Neoplasms ; surgery ; Retrospective Studies ; Robotics
8.The basic structure of heavy-ion tumor therapy facility.
Tong WANG ; Ping XIAO ; Shaowei JIA ; Kehong YUAN ; Hongjie YANG
Chinese Journal of Medical Instrumentation 2014;38(6):427-438
Heavy-ions have the similar characteristic of depth-dose distribution with protons, but exhibit enhanced physical and radiobiological benefits. With increasing development in technical and clinical research, more facilities are being installed in the world. At the same time, many critical techniques of heavy-ion therapy facility were optimized and completed. This paper classified and reviewed the basic structure of heavy-ion system equipments, especially the accelerator, gantry, nozzle , TPS.
Cancer Care Facilities
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Heavy Ion Radiotherapy
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instrumentation
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Humans
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Neoplasms
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therapy
9.Effect of Compound Zaofan Pills on the Hemopoietic Function in Mice with Radiation Injury
Yang XIAO ; Songwen LI ; Weiwei REN ; Yuan ZHANG
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(06):-
Objective To observe the effect of compound Zaofan Pills on the recovery of hemopoietic function in mice with radiation injury.Methods Three days after gastric infusion of compound Zaofan Pills 40 mg/mL (1 g/kg),the mice were treated with radiation of 60Co, 5 Gy per day. After 10 days of radiation, peripheral blood counting ,CFU-GM,BFU-E,CFU-E,CFU-S and the content of 3H-TDR integrated into DNA were tested.Results After treatment,compound Zaofan Pills increased the count of white blood cells, red blood cells and platelet, elevated CFU-GM,BFU-E and CFU-E and enhanced the content of 3H-TDR integrated into DNA (P 0.05).Conclusion Compound Zaofan Pills can promote the recovery of hemopoietic function in mice with radiation injury.
10.Research of the mechanism of pre-B-cell colony-enhancing factor in pulmonary vascular endothelial permeability increasing after CPB
Yuan ZENG ; Wei YANG ; Xiaoqiang ZHANG ; Bin LI ; Xiao DONG
Chongqing Medicine 2013;(28):3388-3389,3392
Objective To investigate the mechanism of PBEF in pulmonary vascular endothelial permeability increasing after car-diopulmonory bypass ,in order to provide the basis for a better lung protective measures during cardiopulmonary bypass .Methods Animal models were established ,group A :the rats were transfected with the lentiviral AD-PBEFshRNA ;group B :the rats were took 30 min deep hypothermic circulatory arrest ;group C :the rats were took 30 min deep hypothermic circulatory arrest ,then trans-fected with the lentiviral AD-PBEFshRNA ;control group :the rats were anesthetized and established CPB tube ,without CPB by-pass .Lung tissue was detected with Western blotting and ELISA .Results PBEF ,phosphorylation of P38MAPK ,ERK ,MLC ,VE-cadherin ,FAK in group C had significant difference with group A ,B and the control group(P<0 .05) .VEGF ,MMP2 ,MMP9 ,W/D in group C had significant difference with group A ,B and the control group(P<0 .05) .The pathological results showed that rat lung tissue of the control group was normal ,while in group C ,it had severe pathological damage ,the pathological damage degree in group A ,B reduced compared to group C .Conclusion PBEF can through MAPK/PI3K-Akt/VEGF signaling pathway ,increase pulmonary vascular endothelial permeability .