1.Cases of Application of Buluo Buguan Decoction in Treatment of Kidney Diseases by SHAO Zhao-di
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(11):104-106
Buluo Buguan Decoction originates from ZHANG Xi-chun's book Yi Xue Zhong Zhong Can Xi Lu, with the functions of astringent, removing blood stasis, and vein relaxing. The original major functions of this decoction are to treat chronic hemoptysis and hematemesis. In long-term clinical practice, Professor SHAO found that the modified decoction showed significant positive outcome in the treatment of hematuria, nocturnal emission, spontaneous sweating, night sweats, and allergic purpura nephritis, with good efficacy.
2.Morphology of the soft palate in normal individuals when pronouncing: a digital cephalometric study.
Guo LI ; Hu WANG ; Kai BA ; Zhen-yu YANG ; Ming-xia LI ; Yuan-yuat LIU ; Meng YOU
West China Journal of Stomatology 2011;29(2):136-138
OBJECTIVETo investigate the morphology of the soft palate in normal individuals with digital radiography, when they pronounced the high vowel of "i", and to provide the references for therapy of the cleft palate.
METHODSIn this study, the sample comprised 27 normal subjects. With the digital cephalometry, the morphology of the soft palate when pronouncing the high vowel of "i" was observed. And the dimensional difference of the soft palate when pronouncing between different gender was studied.
RESULTSWhen pronouncing the high vowel of "i", the morphology of the soft palate was like the shape of the knee. And it could be divided into two parts: horizontal and vertical. The length of the vertical part in male group was (24.92 +/- 2.03) mm, the length of the vertical part in the female group was (20.66 +/- 2.77) mm. The length of the vertical part was different between male and female group (P < 0.001).
CONCLUSIONThe morphology of the palate when pronouncing the high vowel of "i" is similar. And the velar length of the vertical part of the male is longer than the female.
Cephalometry ; Cleft Palate ; Female ; Humans ; Male ; Palate, Soft
3.Effect of nano-granule titanium films on synthesis of osteoblasts.
Kai BA ; Jing ZHANG ; Hu WANG ; Yuan-yuan LIU ; Zhen-yu YANG ; Ming-xia LI ; Wei LI ; Jing-wei MIAO
West China Journal of Stomatology 2009;27(6):592-594
OBJECTIVETo compare the synthetic ability of osteoblasts on the surface of different nano-granule titanium films and investigate the correlation between nanophase titanium films and cellular biocompatibility.
METHODSFour different nano-granule titanium films were produced by direct current magnetron sputtering, at ambient, 100 degrees C, 250 degrees C, 380 degrees C substrate temperature, respectively. Rat osteoblasts were seeded on the surface of four treated groups of titanium film samples and non-treated Ti sample(control group). The production of osteocalcin (OC) in all five groups were detected by using double antibody sandwich enzyme-linked immunosorbent assay.
RESULTSThe production of OC increased gradually from day 7 to day 14 in all groups. In the control group, it showed significant differences with other five groups on day 7. On day 14, the production of OC in 100 degrees C group was the highest, and it showed significant differences with 380 degrees C, control group and blank group. In 250 degrees C group, the production of OC also showed significant differences with 380 degrees C, control group and blank group (P < 0.05).
CONCLUSIONTitanium with nano-modified surface had good biocompatibility and different nano-granule titanium films could affect the synthesis of osteoblasts.
Animals ; Osteoblasts ; Osteocalcin ; Rats ; Surface Properties ; Titanium
4.Port-Site Metastases and Chimney Effect of B-Ultrasound-Guided and Laparoscopically-Assisted Hyperthermic Intraperitoneal Perfusion Chemotherapy.
Ming Chen BA ; Hui LONG ; Xiang Liang ZHANG ; Yuan Feng GONG ; Zhao Fei YAN ; Shuai WANG ; Yun Qiang TANG ; Shu Zhong CUI
Yonsei Medical Journal 2017;58(3):497-504
PURPOSE: CO₂ leakage along the trocar (chimney effect) has been proposed to be an important factor underlying port-site metastasis after laparoscopic surgery. This study aimed to test this hypothesis by comparing the incidence of port-site metastasis between B-ultrasound-guided and laparoscopically-assisted hyperthermic intraperitoneal perfusion chemotherapy (HIPPC). MATERIALS AND METHODS: Sixty-two patients with malignant ascites induced by gastrointestinal or ovarian cancer were divided into two groups to receive either B-ultrasound-guided or laparoscopically-assisted HIPPC. Clinical efficacy was assessed from the objective remission rate (ORR), the Karnofsky Performance Status (KPS) score, and overall survival. The incidence of port-site metastasis was compared between the two groups. RESULTS: Patients in the B-ultrasound (n=32) and laparoscopy (n=30) groups were comparable in terms of age, sex, primary disease type, volume of ascites, and free cancer cell (FCC)-positive ascites. After HIPPC, there were no significant differences between the B-ultrasound and laparoscopy groups in the KPS score change, ORR, and median survival time. The incidence of port-site metastasis after HIPPC was not significantly different between the B-ultrasound (3 of 32, 9.36%) and laparoscopy (3 of 30, 10%) groups, but significantly different among pancreatic, gastric, ovarian, and colorectal cancer (33.33, 15.79, 10.00, and 0.00%, p<0.001). CONCLUSION: The chimney effect may not be the key reason for port-site metastasis after laparoscopy. Other factors may play a role, including the local microenvironment at the trocar site and the delivery of viable FCCs (from the tumor or malignant ascites) to the trauma site during laparoscopic surgery.
Ascites
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Colorectal Neoplasms
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Drug Therapy*
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Humans
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Incidence
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Karnofsky Performance Status
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Laparoscopy
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Neoplasm Metastasis*
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Ovarian Neoplasms
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Perfusion*
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Surgical Instruments
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Treatment Outcome
5.Impact of acupoint heat-sensitive moxibustion on lung function and life quality of patients with chronic persistent bronchial asthma: a randomized controlled study.
Ba-si OUYANG ; Jie GAO ; Gang SUN ; Ming-zhi PU ; Yuan-jian WU ; Chun FAN ; Ling-ling JI
Chinese Acupuncture & Moxibustion 2011;31(11):965-970
OBJECTIVETo observe the impact of heat-sensitive moxibustion on lung function in chronic persistent bronchial asthma and analyze its effect on the improvement of life quality as well as compare its efficacy with Seretide inhaler.
METHODSFifty-seven cases were divided into a heat-sensitive moxibustion group (28 cases) and a Seretide group (29 cases) according to the random number table. In heat-sensitive moxibustion group, the therapy of heat-sensitive moxibustion was applied to the regions at the level of Feishu (BL 13) and Geshu (BL 17), or to the heat-sensitized points in the region 6 cun lateral from the 1st and 2nd intercostal spaces in the chest. The treatment was given continuously for 8 days, once per day, 12 treatments should be ensured in the later 22 days of the 1st month. In the later two months since then, 15 treatments should be ensured each month (< or = 1 treatment each day). In Seretide group, Seritide manufactured in GlaxoSmithKLine was used, one inhalation each time, twice per day. The cases in both groups were received treatment for 3 months. The changes in lung function such as forced expiratory volume one second (FEV1), TCM symptoms score, Asthma Control Test (ACT) and St George's Respiratory Questionnaire (SGRQ) were assessed and compared between two groups and within group separately.
RESULTSLung function as FEV1 was improved in either group (P < 0.05, P < 0.01). The terminal improvement effects on symptoms of Chinese medicine, life quality and others were same between two groups (all P > 0.05). But the improvements in general situation, chills, fever and sweating in heat-sensitive moxibustion group were superior to those in Seretide group (both P < 0.05). Concerning to the improvement in respiratory symptoms, the effect of Seretide was better than that of heat-sensitive moxibustion (P < 0.05).
CONCLUSIONHeat-sensitive moxibustion improves lung function, relieves clinical symptoms and benefits life quality for patients with chronic persistent bronchial asthma. It's efficacy on the disease is equal to the internationally-recognized effect of Seretide.
Acupuncture Points ; Adult ; Asthma ; physiopathology ; therapy ; Female ; Humans ; Lung ; physiopathology ; Male ; Middle Aged ; Moxibustion ; Quality of Life
6.Determination of urine oxalate level in rats with renal calcium oxalate calculus by high-performance liquid chromatography.
Qiu-shi CAO ; Yuan-ming BA ; Jun-hua LUO ; Qi DAI
Acta Academiae Medicinae Sinicae 2015;37(1):82-87
OBJECTIVETo establish a method of high-performance liquid chromatography (HPLC) for determining the urine oxalate levle in rats with renal calcium oxalate calculus.
METHODSTotally 24 SPF Wistar healthy male rats were randomly divided into control group(n=12)and ethylene glycol (EG) group (n=12). Rats in EG group were administered intragastrically with 2% ammonium chloride (AC)2 ml/rat per day+1% ethylene glycol (EG), along with free access to drinking water.The control group was fed with deionized water, along with the intragastric administration of normal saline (1 ml per day). Twenty-eight days after modelling, the 24-hour urine samples were collected, and the urine oxalic acid levels were determined using HPLC and the results were compared with those of catalytic spectrophotometry using oxidation of methyl. During the HPLC, the samples were separated on Aglient 5TC-C18 (250×4.6 mm,5 Μm), eluted with mixture of methanol (0.1 mol/L) and ammonium acetate (15:85) at 1.2 ml/min, and detected at 314 nm, with the column temperature being 20 ℃.
RESULTSThe standard curves of high and low concentrations of oxalic acid were y=5909.1x+378730, R² =0.9984 and y=7810.5x-16635, R² =0.9967,respectively. The lowest detectable concentration in this method was 5 Μg/ml. The linear high concentration range of oxalate stood at 62.50-2000.00 Μg/ml, and the linear low concentration range of oxalate stood at 6.25-100.00 Μg/ml. Its average recovery was 95.1%, and its within-day and day-to-day precisions were 3.4%-10.8% and 3.8%-9.4%. Both HPLC and catalytic spectrophotometry showed significantly higher urinary oxalic acid concentration and 24 h urine oxalate level in EG group compared with the control group [urinary oxalic acid concentration: (736.35 ± 254.52) Μg/ml vs.(51.56 ± 36.34) Μg/ml,(687.35 ± 234.53) Μg/ml vs.(50.24 ± 42.34) Μg/ml;24 h urine oxalate level: (11.23 ± 4.12)mg vs.(0.87 ± 0.45)mg,(9.89 ± 3.55)mg vs. (0.77 ± 0.65)mg; all P<0.01]. No statistically significant difference was observed in the results of urinary oxalate concentration and 24 h urine oxalate level between HPLC and potassium chromate oxidation of methyl red spectrophotometry (all P>0.05).
CONCLUSIONHPLC is a simple, rapid, and precise method in detecting urine oxalate level in rats with renal calcium oxalate calculus, with high recovery rate.
Acetates ; Animals ; Azo Compounds ; Calcium Oxalate ; Calculi ; Chromates ; Chromatography, High Pressure Liquid ; Kidney ; Male ; Oxalates ; Potassium Compounds ; Rats ; Rats, Wistar ; Spectrophotometry ; Water
7.Effect of Different Effective Parts of Taohe Chengqitang on Synthesis and Degradation of Extracellular Matrix in HK-2 Cells Induced by TGF-β1
Shan-shan ZHOU ; Zhong-zhu AI ; Wei-nan LI ; Yuan-ming BA
Chinese Journal of Experimental Traditional Medical Formulae 2020;26(19):127-134
Objective:To explore the effect of different effective parts of Taohe Chengqitang on the synthesis and degradation of extracellular matrix in human kideny-2(HK-2) cells induced by transforming growth factor-
8.Active Components and Mechanism of Rhei Radix et Rhizoma on Renal Fibrosis Based on Network Pharmacology
Shan-shan ZHOU ; Zhong-zhu AI ; Wei-nan LI ; Yuan-ming BA
Chinese Journal of Experimental Traditional Medical Formulae 2020;26(10):163-172
Objective::To explore the active components, potential targets and signaling pathways of Rhei Radix et Rhizoma in the treatment of renal fibrosis based on the network pharmacology method, and then to verify the target genes
9.Fluoride Exposure, Follicle Stimulating Hormone Receptor Gene Polymorphism and Hypothalamus-pituitary-ovarian Axis Hormones in Chinese Women.
Ming Xu ZHAO ; Guo Yu ZHOU ; Jing Yuan ZHU ; Biao GONG ; Jia Xiang HOU ; Tong ZHOU ; Li Ju DUAN ; Zhong DING ; Liu Xin CUI ; Yue BA
Biomedical and Environmental Sciences 2015;28(9):696-700
The effects of fluoride exposure on the functions of reproductive and endocrine systems have attracted widespread attention in academic circle nowadays. However, it is unclear whether the gene-environment interaction may modify the secretion and activity of hypothalamus-pituitary- ovarian (HPO) axis hormones. Thus, the aim of this study was to explore the influence of fluoride exposure and follicle stimulating hormone receptor (FSHR) gene polymorphism on reproductive hormones in Chinese women. A cross sectional study was conducted in seven villages of Henan Province, China during 2010-2011. A total of 679 women aged 18-48 years were recruited through cluster sampling and divided into three groups, i.e. endemic fluorosis group (EFG), defluoridation project group (DFPG), and control group (CG) based on the local fluoride concentration in drinking water. The serum levels of gonadotropin releasing hormone (GnRH), follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) were determined respectively and the FSHR polymorphism was detected by real time PCR assay. The results provided the preliminary evidence indicating the gene-environment interaction on HPO axis hormones in women.
Adolescent
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Adult
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Age Factors
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Asian Continental Ancestry Group
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China
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Cross-Sectional Studies
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Estradiol
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blood
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Female
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Fluoridation
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adverse effects
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Fluorides
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administration & dosage
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adverse effects
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urine
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Follicle Stimulating Hormone
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blood
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Gene-Environment Interaction
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Gonadotropin-Releasing Hormone
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blood
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Humans
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Hypothalamus
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physiology
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Luteinizing Hormone
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blood
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Middle Aged
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Ovary
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physiology
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Pituitary Gland
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physiology
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Polymorphism, Single Nucleotide
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Receptors, FSH
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genetics
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Tobacco Smoke Pollution
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Young Adult
10.Expert consensus on the prevention and treatment of adverse reactions in subcutaneous immunotherapy(2023, Chongqing).
Yu Cheng YANG ; Yang SHEN ; Xiang Dong WANG ; Yan JIANG ; Qian Hui QIU ; Jian LI ; Shao Qing YU ; Xia KE ; Feng LIU ; Yuan Teng XU ; Hong Fei LOU ; Hong Tian WANG ; Guo Dong YU ; Rui XU ; Juan MENG ; Cui Da MENG ; Na SUN ; Jian Jun CHEN ; Ming ZENG ; Zhi Hai XIE ; Yue Qi SUN ; Jun TANG ; Ke Qing ZHAO ; Wei Tian ZHANG ; Zhao Hui SHI ; Cheng Li XU ; Yan Li YANG ; Mei Ping LU ; Hui Ping YE ; Xin WEI ; Bin SUN ; Yun Fang AN ; Ya Nan SUN ; Yu Rong GU ; Tian Hong ZHANG ; Luo BA ; Qin Tai YANG ; Jing YE ; Yu XU ; Hua Bin LI
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2023;58(7):643-656