1.Analysis on the chapter of rehabilitation definition in the fourth edition of rehabilitation medicine textbook
Hong ZHANG ; Yuan JIANG ; Fei LI
Chinese Journal of Medical Education Research 2013;(3):312-314
The definition of rehabilitation should reflect the connotation and extension of rehabilitation medicine system,moreover,special attention should be paid to the process of translation,applications and promotion due to its derivation from Latin.The fourth edition of rehabilitation medicine textbook which published by People's Medical Publishing House described the definition of rehabilitation inaccurately,although integrated the foreign authority definitions.The definition of ‘ re-learning’has been described by the textbook without considering logical sequence,which caused difficulty in explaining and comprehending between teachers and students in class.Besides,application of another term of rehabilitation medicine in the textbook is imprudence.
2.The effects of rosiglitazone on the endothelial regeneration and neointimal formation of balloon injured rat aortic
Yuan YAO ; Hong JIANG ; Chao XU
Chinese Journal of Interventional Cardiology 1996;0(01):-
Objective To investigate the effects of rosiglitazone on the endothelial regeneration and neointimal formation after balloon injury in rat aortic.Methods Endothelial denudation of aorta in SD rats were performed with 2 F Fogarty balloon catheter.Male Rats were randomly divided into the sham-operated group,the control group,and the RSG group.Aortic tissues were harvested 7 days and 14 days after the injury.The endothelial regeneration rate,serum NO level,IA/MA ratio and PCNA expression index were detected.Results RSG enhanced the reendothelialization of the injured aorta determined by Evans blue staining.The RA/TA ratio on the 7~(th) day and the 14~(th) day were 38.20% and 75.20%(P
3.Impacts of electroacupuncture combined with ultraviolet therapy on cytokines of herpes zoster at the acute stage in patients.
Hong ZHANG ; Xiaodan XU ; Jiao YANG ; Yuan JIANG
Chinese Acupuncture & Moxibustion 2015;35(2):145-148
OBJECTIVETo observe the effect of electroacupuncture (EA) combined with ultraviolet therapy on herpes zoster at the acute stage and the impacts on serum interleukin 2 (IL-2), interleukin 6 (IL-6) and interleukin 10 (IL-10) in the patients.
METHODSThirty-four patients of herpes zoster were randomized into a medicine group and a combined therapy group, 17 cases in each one. In the medicine group, the intravenous drops with acyclovir injection, muscular injection with cobamamide and the topical with acyclovir ointment were applied. Additionally, TDP was radiated locally. In the combined therapy group, on the basis of the treatment as the medicine group, EA and ultraviolet therapy were supplemented. The duration of treatment was 10 days in the two groups. Before and after treatment, blister relief, incrustation time and the visible analogue scale (VAS) were recorded in the two groups. The clinical efficacy was assessed in the two groups and the levels of serum IL-2, IL-6 and IL-10 were determined in the two groups.
RESULTSIn the combined therapy group, the time of blister relief and incrustation was earlier apparently than that in the medicine group (both P<0.05). VAS score after treatment were reduced as compared with that before treatment in the two groups (both P<0.01), and the reducing amplitude in the combined therapy group was larger than that in the medicine group (P<0.01). The total effective rate was 94. 1% (16/17) in the combined therapy group, higher than 76.4% (13/17) in the medicine group (P<0.05). After treatment, IL-2 levels were increased as compared with those before treatment in the two groups (both P<0.05), the levels of IL-6 and IL-10 were reduced obviously as compared with those before treatment in the two groups (all P<0.01). After treatment, the levels of IL-6, IL-10 were reduced much more apparently in the combined therapy group as compared with those in the medicine group (both P<0.05).
CONCLUSIONEA combined with ultraviolet irradiation more rapidly and effectively relief the symptoms of herpes zoster, significantly relief pain, shorten the duration of sickness, improve the body immunity and reduce nerve injury.
Acyclovir ; administration & dosage ; Adult ; Combined Modality Therapy ; Electroacupuncture ; Female ; Herpes Zoster ; blood ; drug therapy ; therapy ; Humans ; Interleukin-10 ; blood ; Interleukin-2 ; blood ; Interleukin-6 ; blood ; Male ; Middle Aged ; Treatment Outcome ; Ultraviolet Therapy
4.Relationship between serum hepatitis B virus covalently closed circle DNA and clinical stage as well as pathological grade of chronic hepatitis B in children
Xiaoyan LEI ; Yonghong SUN ; Julan YANG ; Hong YUAN ; Huiling JIANG
Chinese Pediatric Emergency Medicine 2013;20(3):292-294
Objective To study the relationship between serum hepatitis B virus covalently closed circle DNA (HBV cccDNA) as well as liver function and liver tissue pathological changes in children with chronic hepatitis B.Methods One hundred and twenty-four HBV-DNA positive children with hepatitis B were enrolled.Among 124 patients,65 cases were HBV carriers,59 cases were chronic hepatitis (mild in 31 cases,moderate in 18 cases and severe in 10 cases).HBV cccDNA in serum and liver function were detected,46 of which underwent liver biopsy and liver tissue inflammation and fibrosis grading classification was made.Results In moderate and severe cases,positive rates of serum HBV cccDNA (77.8%,100%) were higher than those of the HBV carriers and mild cases (32.3%,54.8%) (x2 =25.429,P < 0.01),indicating more severe illness in children,detection rate of serum HBV cccDNA was higher.ALT,AST,and TBIL were higher in serum HBV cccDNA positive group than those of negative group[(95.6 ± 18.2) U/L vs (52.5 ± 17.7) U/L,(88.8 ±20.3) U/L vs (48.4 ±21.4) U/L,(68.4 ±24.6) μmol/L vs (28.3 ± 23.9) μmol/L](t =15.572,10.750,17.067,P < 0.01).Serum HBV cccDNA and liver inflammatory activity and fibrosis showed no significant correlationship.Conclusion Serum HBV cccDNA is a sensitive indicator of viral replication,the more severe the disease situation,the peripheral HBV cccDNA detection rate is higher.But it is not entirely consistent with liver inflammation and fibrosis,so it can not completely reflect the degree of liver damage.
5.Plasma brain natriuretic peptide levels in elderly male patients with type 2 diabetes and primary osteoporosis
Hexin ZHENG ; Ying JIANG ; Hong HUANG ; Fang YUAN ; Tianfeng WU
Chinese Journal of Geriatrics 2013;(3):263-266
Objective To evaluate plasma natriuretic peptide brain (BNP) levels in elderly male patients with type 2 diabetes and primary osteoporosis.Methods A total of 122 elderly male patients with type 2 diabetes were divided into 3 groups according to bone mineral density(BMD):normal group (41 cases),osteopenia group (40 cases) and osteoporosis group (41 cases),and another 33 age matched healthy subjects as control group.Plasma BNP levels were determined by ELISA.Results Plasma BNP levels in osteoporosis group [(1.95 ± 0.49) pmol/L] and osteopenia group [(1.64±0.48) pmol/L] were significantly elevated compared with that in normal group [(1.32±0.38) pmol/L] and control group [(1.26±0.39) pmol/L] (all P<0.01).There was a statistical difference between osteoporosis group and osteopenia group (t=3.539,P<0.05),and also between normal group and control group (t=2.726,P<0.05).Plasma BNP levels had negative correlation with BMD of 2na-4th lumbar vertebra (r=-0.366) and femoral neck (r=-0.375),body mass index (r=-0.288) and estrodiol (E2) (r=-0.352) (all P<0.05); while had a positive correlation with parathyroid hormone (PTH) (r=0.353,P<0.05).Conclusions With BMD declining,plasma BNP levels are elevated in elderly male type 2 diabetes,which may be related to the compensatory increase in PTH and the decrease in estradiol.
6.Electrochemiluminescence Behavior of [ Ru(bpy) 3 ] [4-(Clph) 4 B] 2/N,N,N',N'-Tetrakis(propyl)-pentanediamine Nanopaticles Modified Electrode
Hong RAN ; Ping JIANG ; Baozhan ZHENG ; Hongyan YUAN ; Dan XIAO
Chinese Journal of Analytical Chemistry 2015;(11):1708-1715
A new organic-soluble co-reactant of N,N,N’,N’-tetrakis(propyl)-pentanediamine (TPPD) was synthesized and co-immobilized with tris ( 2, 2’-bipyridine ) ruthenium ditetrakis ( 4-chlorophenyl ) borate ([Ru(bpy)3][4-(Clph)4B]2) on an indium tin oxide (ITO) electrode for electrochemiluminescent (ECL) study. The hydrophobicity of TPPD prevented its leakage from the electrode surface, thus the long-term stability of the ECL electrode was enhanced. The TPPD/[Ru(bpy)3][4-(Clph)4B]2 modified-ITO electrode exhibited strong, stable and reproducible ECL signal. The ECL signal could be quenched efficiently by phenol with a quenching efficiency of 95. 4% in the presence of 0. 1 mmol/L phenol, demonstrating the potential of the modified electrode in determination of phenolic compounds. The transient-state of the electrogenerated chemiluminescence reaction was also investigated, which revealed that the TPPD/[Ru(bpy)3][4-(Clph)4B]2 modified-ITO electrode had a longer lifetime than conventional TPA-Ru(bpy)2+3 co-reactant system.
7.Analysis of mental status assessment of patiens with dento-maxillofacial deformities
Weijun YUAN ; Lili JIANG ; Bixia WANG ; Dedong YU ; Hong RUAN
Chinese Journal of Practical Nursing 2014;30(8):64-66
Objective To study the mental status of dento-maxillofacial deformities patients for orthognathic-orthodontic treatment,assess the testing results,and provide reference for doctors and nurses to evaluate mental features of patients.Methods 79 patients from a three-level and first-class hospital in Shanghai were collected from February 2011 to January 2012,who were to undergo orthognathic-orthodontic treatment.All the subjects filled in MMPI questionnaire before the operation.Results Scores of F and Pa subscales in male were significantly lower than the national norm.Scores of K and Mf subscales in female were significantly higher than the national norm.Scores of L,F,Hs,D,Pd,Pa,Pt,Sc,Si subscales were significantly lower than the national norm.Scores of F,Pa,Sc,Ma subscales in male were significantly higher than female.Scores of Mf subscales in female were significantly higher than male.Conclusions The whole personality of dento-maxillofacial deformities patients are normal.However,individualized personality deviation and psychological problems exist,including personality characteristics among different genders.
8.Serum and cord leptin levels in pregnancy-induced hypertension women
Hong LIU ; Xiaoya JIANG ; Yuan SUN ; Wenjin WU ;
Journal of Third Military Medical University 2003;0(08):-
Objective To investigate the changes of serum and cord leptin levels in pregnancy induced hypertension(PIH) women and the significance. Methods Immunoradioassay was used to measure the serum and cord blood leptin levels in 50 PIH women (PIH group) and 80 normal pregnant women(normal group). The correlative analysis of the results was performed. Results (1) Serum leptin level in PIH women was (40.02?8.92)?g/L, notably higher than that (24.67?5.23) in normal pregnant women( P
9.Analysis with capability of responding to emerging infectious diseases among medical university students in Chongqing city
Jiajia JIANG ; Yuan YANG ; Hong WANG ; Xiaojun TANG ; Fan ZHANG
Chongqing Medicine 2017;46(6):809-811
Objective To take Ebola virus disease (EVD) as an example and analyze the capability of responding to emerging infectious diseases among medical university students in Chongqing city.Methods Medical university students of 2 094 in Chongqing were selected and investigated by cluster sampling.Questionnaire content includes social demographic information,knowledge,attitude,practice (KAP) and related factors about EVD.The variables of the respondents were described using mean and standard deviation for continuous variables and frequency distributions for categorical variables.Influencing factors were analyzed by using multiple-linear regression model.Results The average scores of KAP regarding EVD were 9.51 ±-3.97,5.93± 1.85,3.35 ±1.43,respectively.Multiple-linear regression analysis showed that the influencing factors of KAP regarding EVD were gender (x2 =0.773,P=0.000),residence (x2 =0.886,P=0.014) and health habits (x2 =0.316,P=0.008);gender (x2 =0.474,P=0.000),grade (x2 =0.118,P=0.024),residence (x2 =0.401,P=0.016) and health habits (x2 =0.307,P=0.000);gender (x2 =0.223,P=0.001),major (x2 =0.152,P=0.000) and health habits (x2 =0.231,P=0.000).Conclusion The capability of responding to emerging infectious diseases is not optimistic among medical university students.Medical universities should perform effective intervention according to the characters of different clusters.
10.Content Determination of Ursolic Acid in Pedo-stomach-invigorating&Digestion-promoting Granule by TLC-scanning Method
Shubei WANG ; Hengjie YUAN ; Hong JIANG ; Ruipeng SHEN
China Pharmacy 2005;0(19):-
OBJECTIVE:To establish a method for the determination of ursolic acid in pedo-stomach-invigorating&digestion-promoting granule.METHODS:The determination was performed by TLC-scanning method in which chloro-form-acetone-glacial acetic acid(18∶2∶0.2)was used as developing solvent,and10%sulphuric acid ethanol solution was taken as developer,which were baked under110℃until limpid prunosus spots were occurred,the scanning method was dual wavelength reflection zigzag scanning with detection wavelength at520nm,reference wavelength at700nm,linearity parameter Sx=3and slit size at0.4mm?0.4mm.RESULTS:Ursolic acid has a good linear relation with peak area score when its sample size was within the range of2?g~10?g(r=0.9996),the average recovery is97.8%(RSD=1.4%).CONCLUSION:This me_ thod can be served as a quality control for pedo-stomach-invigorating&digestion-promoting granule.