Child ; Child, Preschool ; Humans ; Leukemia ; immunology ; prevention & control ; Vaccination

ObjectiveTo observe the effect of nursing interventions on improvement of psychological actions and quality of life of patients with Alzheimer disease. Methods50 patients with senile dementia diagnosed in our hospital were chosen.They were divided into the observation group and the control group with 25 patients in each group.All patients were taken with AD routine nursing care after admission.The observation group was taken with rehabilitation nursing interventions based on AD routine nursing care.The mini-mental state examination (MMSE)and the daily life ability scale (ADL)were used to evaluate the quality of life after nursing intervention. ResultsThe patients' MMSE score in the observation group was significantly higher than the control group,the difference was statistically significant.The ADL score of the observation group was significantly lower than the control group,the difference was statistically significant. ConclusionsThe use of integrated care intervention can significantly improve the cognitive function in AD patients,and improve daily living ability and quality of life significantly.

Objective Vascular mild cognitive impairment(VaMCI) refers to mild cognitive impairment caused by or associated with vascular causes.This study aims to investigate the characteristics of the cognitive impairment in patients with vascular mild cognitive impairment (VaMCI).Methods Seventy-five patients with VaMCI(VaMCI group) and 38 healthy old subjects whose age, sex and education level match the VaMCI group patients(control group) were recruited from the department of Neurology, Beijing Chaoyang Hospital, Capital Medical University between Jan 2016 and June 2016.The neuropsychological examinations were used to evaluate the severity of cognitive impairment, specifically including the Minimum Mental State Examination(MMSE), Montreal cognitive assessment scale(MoCA), Clinical Dementia Rating(CDR), Activity of Daily Living Scale(ADL), Hachinski ischemic score table, Hamilton Depression Scale(HAMD) and Auditory Verbal Learning Test(AVLT).The Fazekas scale was used to assess the severity of white matter lesions, and the medial temporal lobe atrophy rating scale(MTA) was used to evaluate the atrophic severity of medial temporal lobe.Results The overall cognitive function score in VaMCI group was significantly lower than the control group [MMSE [25.7±2.3 vs 28.4±2.0] MoCA [22.8±3.9 vs 26.3±3.7]], the differences was statistically significant(P<0.05);as well as the AVLT-I [5.1±1.0 vs 8.9±1.9], AVLT-D [3.7±1.0 vs 9.8±1.5] and AVLT-R [7.6±1.9 vs 12±1.5] scores in VaMCI group was significantly lower than the control group, the differences was statistically significant(P<0.05), which suggested patients with VaMCI have overall cognitive impairment, especially memory impairment.But Fazekas and MTA scores in VaMCI groups were higher than the control group, the differences was statistically significant(P<0.05).Correlation analysis showed that the scale of medial temporal lobe atrophy had a negative relationship with the performance of MoCA (r=-0.434,P=0.002).Conclusion Our findings demonstrate patients with VaMCI have significant cognitive impairment, especially memory impairment, which may be correlated to the severity of the white matter lesions and the medial temporal lobe atrophy.

Arteriovenous fistula (AVF) and arteriovenous malformation (AVM) are the common intracranial vascular malformations. The experimental models of AVF and AVM include animal models, in vitro models and biomathematical models. These models could be used to investigate the pathophysiological characters of AVF and AVM, to simulate the clinical treatment, and to examine the materials for embolization therapy. This article reviewed the formation of these models, evaluated their advantages and disadvantages, and briefly introduced their applications.

Helicobacter Infections ; complications ; Helicobacter pylori ; Hematologic Diseases ; complications ; Humans

Adult ; Arterio-Arterial Fistula ; complications ; Coronary Vessels ; pathology ; Embolization, Therapeutic ; Humans ; Male ; Myocardial Ischemia ; etiology ; therapy ; Pulmonary Artery ; pathology

Objective To explore the effect of percutaneous interventional radiofrequency thermocoagulation target ablation combined with nerve block in the treatment of lumbar disc herniation, and to provide reference for clinical application. Methods Randomly selected from May 2015 to May 2017 treatment of lumbar disc herniation in 150 cases, according to the different treatment methods were divided into observation group and control group. The observation group of 78 cases, including percutaneous interventional radiofrequency thermocoagulation target ablation combined with nerve block treatment; the control group of 72 cases, simply accept the nerve block treatment. The degree of lumbar dysfunction was evaluated by Osw estry Lumbar Dysfunction Index (ODI) before and after treatment. The efficacy of the two groups was evaluated by modified MacNab score. Adverse reactions were observed during the two groups. Results There was no significant difference between the two groups. After 2 weeks of treatment, the scores of ODI were significantly lower than those before treatment (P<0.05). The ODI score of the observation group was significantly lower than that of the control group (P<0.05). The effective rate was 96.2% (75/78) and the excellent and good rate was 91.03% (71/78). The effective rate was 90.28% (65/72) and the excellent and good rate was 65.28% (47/72). The excellent and good rate of the observation group was significantly higher than that of the control group (P<0.05). There were no significant adverse reactions in the two groups. Conclusion Percutaneous interventional radiofrequency thermocoagulation target ablation combined with nerve block treatment of lumbar disc herniation significantly, high safety.

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Objective To observe the effect of laser of Q Switch Nd:YAG 1 064nm wave length laser in the treatment of naevus fusco caerulens zygomaticus. Methods Since October 2000, forty nine cases of naevus fusco caerulens zygomaticus had been treated once every three months. Results Thirty two cases had been treated three times, and seventeen cases, four times. The total effective rate was 100 %. The pigmentation of all the cases were darker after the first treatment, later as the treatment progressed, the pigment became lighter. No pigment loss was seen. Conclusion Q switch Nd:YAG 1 064 nm wavelength laser has a good effect in the treatment of naevus fusco caerulens zygomaticus. It is safe and reliable.