Early detection of pancreatic cancer is difficult and most of patients with pancreatic cancer present with locally advanced stage disease or distant metastasis on diagnosis. Micrometastasis occurs in the majority of pancreatic cancers larger than 2 cm in diameter and making early diagnosis and treatment essential to improve the prognosis. Small pancreatic tumors less than 2 cm in diameter can be missed on transcutaneous ultrasound, CT and MRI. Endoscopic ultrasound (EUS) has been considered the most sensitive modality in evaluation of pancreatic lesions. It can be placed in close proximity to the pancreas and provide real-time, high resolution imaging using a high frequency ultrasound probe to find lesions as small as 5 mm. Recently, small pancreatic tumors have been increasingly detected with the widely used EUS. The development of new techniques such as EUS elastography, contrast-enhanced harmonic EUS (CEH-EUS) and fine needle aspiration biopsy (EUS-FNAB) have enhanced the ability of EUS in detection of small solid pancreatic tumors as well as in differentiation of malignancies from benign tumors.

Objective To investigate whether intervention with two different dosage of atorvastatin may benefit to plasma level of fibrinogen (Fg) in patients with acute cerebral infarction. Methods One hundred and two patients with acute cerebral infarction were randomly assigned into three groups:the control group (33 cases) treated without lipid-lowering drugs, 10 rag (30 cases) and 20 mg (39 cases) atorvastatin group with 3 days of treatment. Before and after the treatment, the plasma levels of Fg and lipids were detected.Results The treatment of 10 mg atorvastatin did not significantly decrease the level of Fg. Compared to the control group, the level of Fg was markedly reduced by 20 mg atorvastatin (21.6% vs 3.2%,P< 0.05). No changes of lipid levels were observed in any group before and after the treatment, whilst there was no relation between the decreasing percentage of Fg and that of TC(r = 0.125 ,P= 0.618), TG(r = 0.147,P = 0.573) or LDL- C (r = -0.279, P = 0.235 ), HDL-C (r = -0.021, P = 0.157). Conclusion Treatment with high dose atorvastatin (20 mg) for 3 days could reduce the level of Fg, and improve the function of vascular endothehum,which may promote the stabilization of atherosclerotic plaque.

Caries is one of the most common chronic progressive oral diseases. TCM medicinal herbs have many advantages compared with traditional dental drugs for caries (such as fluoride). In recent years, cariogenic TCM medicinal herbs have attracted the attention of many domestic and foreign scholars. Caries is not caused by a single factor. The development of caries is closely related to bacterial biofilms that are formed by streptococcus mutans, streptococcus sanguis, actinomyces inside, actinomyces and lactobacillus. Therefore, this article took a brief overview of TCM medicinal herbs and their active ingredients that inhibit the bacterial biofilms.

Objective:To study the effects of 3 extracts from Chinese gall on the growth and metabolism of 6 kinds of oral bacteria.Methods:Through a series of extraction and purification,3 active monomer,gallnut extract gallic acid,methyl gallate and gallic acid ethyl ester were selected.Streptococcus mutansUA159(UA159),Actinomyces viscosus (Av),Porphyromonas gingivalis (Pg),Enterococcus faecalis (Ef),Fusobacterium nucleatum(Fn) and Candida albicans (Ca) were treated by the extracts respectively,The growth and metabolism of the becteria were studied by liguid dilution method.Results:The MIC(mg/ml) of Gallic acid anainst the bacteria was 2.5-5,methyl gallate 2.0-4.0 and gallic acid ethyl ester 1.25-2.5.The extracts at 1 mg/ml could inhibit the growth,acid production and extracellular polysaccharides of the 6 oral pathogens.And ethyl gallate showed the strongest effects.Conclusion:Gallic acid and methyl gallate and ethyl gallate at low concentration may inhibit the growth,acid metabolism and glucose metabolism of oral bacteria.

The changes of cerebral hemodynamics, morphology and hemodynamics of carotid artery in carotid endarterectomy were monitored using transcranial Doppler in combination with color duplex ultrasound. It is helpful to reduce the occurrence of intraoperative cerebral ischaemia and timely guides surgeons to perform the second repair. This article reviews the application values of ultrasonic technology in carotid endarterectomy.

Medical students′ professional spirit cultivation is an important content as well as a basic require-ment of the Preeminent Doctor Education and Training Plan. Currently, there are several problems in medical tal-ents′professional spirit cultivation, such as the unstandardized curriculum, the lack of subjective experience, and the ignorance of the unity of education stages, student differences and coherence. This study intends to explore thedouble teacher method, in which both clinical teaching doctors and medical ethics teachers engage in the medi-cal students′professional spirit cultivation. Its purpose is to build a bridge between medical ethics education in uni-versities and the clinical practice, and further to integrate them through doctors′ and teachers′ joint participation, which will significantly enhance medical students′practice ability of medical moral.

OBJECTIVE:To establish a method for the bacterial endotoxin test of chlorphenamine maleate injection. METHODS: The interference test and bacterial endotoxin test of 28 batches of chlorphenamine maleate injections from 14 manufacturers were carried out in accordance with the bacterial endotoxin test approved by Chinese Pharmacopeia (2005 edition). RESULTS: Diluted to a concentration of below 0.025 mg?mL-1,the samples showed no interference action on bacterial endotoxin test. The limit value of the bacterial endotoxin was 5 EU?mg-1. The results of the bacterial endotoxin test of the 28 batches of samples were all accorded with the standard of the established quality control. CONCLUSION: The established TAL method is applicable for bacterial endotoxin test of chlorphenamine maleate injection.

It is written in statue of population and birth control in Ji Lin province that women who are in legal marriageable age and decide to be terminally single can employ assistecl procreative methods to give birth to one child, which causes profound despondence nationwide. Ties essay discusses the law problems about procreation right in single women in order to improve the law and protect peoples rights.

The promulgation of regulations of coping with public health affairs outbreak offers the powerful legal protection. In order to enhance the consciousness implementary, we must go along with futher discussion of ethical principle in the regulations. By doing this, we expect to enhance the responsibility, collaboration and dedication consciousness of people, then to prevent and control the occurrences of public health affairs outbreak effectively.

With the development of medicine and the raising of people' s health sciousness, the structure of harmoaious medicine ethic views will be more important. It will have great directive meaning on the innovation development of medicine ethincs system, have fatal practical meaning on protesting people's livesand health, and also have far- reaching meaning on the persistent development of health career.