BACKGROUND: Cardiac reserve indicators obtained under quiescent condition are used as evaluating index for cardiac reserve functions. However, most important aspect of cardiac dysfunction in heart failure is not the depressed cardiac performance noted at basal resting states, but rather the loss of cardiac reserve. OBJECTIVE: To develop a data processing and information management system for detecting cardiac reserve indicator with the widely used B mode ultrasound instrument in the ultrasonography field, and to provide guidance for B mode ultrasound instrument perfection. METHODS: General B mode ultrasound instrument as peripherals was connected with the pc by image acquisition card; ultrasound heart image diagnosis and management system including professional heart image acquisition and process and perfect data bank was develop. RESULTS AND CONCLUSION: An efficient and flexible mini picture archiving and communication system system was achieved, which realized image enhancement, geometric parameter measuring, convenient diagnosis report output, archive management and print function. Results demonstrated that with the powerful data process ability of PC, the system could improve the performance of the traditional ultrasound instrument in detecting cardiac reserve, which provide a powerful support for the further study.

Chromosomes, Human, Pair 22 ; Chromosomes, Human, Pair 9 ; Humans ; Leukemia, Promyelocytic, Acute ; genetics ; Male ; Middle Aged ; Translocation, Genetic

AIM: To investigate clinical effects of local resection of eyelid tumors and pathological examination or frozen section examination as well as the stage I recovery.
METHODS: For all 92 cases 92 eyes of eyelid tumor patients who underwent local resection, reconstruction in stage Ⅰ and routine pathological examination ( 37 cases of suspected malignant tumors using frozen section examination. If it was malignant, excision by Moths surgery) . Using free palate mucosa autograft in stage I or reconstruction by Hughes surgery combined with eye flaps repaired eyelid defects.
RESULTS: The postoperative pathological diagnosis:52 cases were benign tumors, and 40 cases malignant tumors. All cases of eye flaps and hard palate mucosa grafts were survived. Followed up for more than 6mo, no tumor were recurred. The appearance and function of eyelid were satisfactory.
CONCLUSION: In this group of cases, nearly half of eyelid tumors are malignant tumors. It should be treated and operated as early as possible. For suspected malignant tumors, we use frozen section examination to confirm its properties in order to excision cleanly in stageⅠ, reducing the recurrence and metastasis. According to the eyelid defect after resection, we could do repair operation in stage Ⅰ. The inner larger defect is repaired by using hard palate mucosa transplantation or Hughes surgery. The outer layer of the eyelid defect is repaired by using eye flap glide, the free flap, the kite flap, the simple suture, etc. It should be careful when using the hard palate mucosa transplantation in the upper eyelid defect.

Strain QJ16,one of some methanotrophic bacteria isolated from soil samples utilizing the separate device designed by our laboratory;was studied in detail and identified as one of the Genus methylomonas through 16S rDNA sequencing and comparison. The culturing and reaction conditions for methane utilization of this strain were investigated. The results indicated that the optimal conditions for the growth of strain QJ16 were methane gas as carbon source and the coexistence of NH4Cl and KNO3 as nitrogen source,the cultivation temperature of 30℃ and medium initial pH 6～7,and the optimal Cu2+ concentration of 15 ?mol/L.

Teaching purpose, teaching content, experiment and examination forms etc. were discussed, and how to practice the teaching of the public selective course Nutriology of Traditional Chinese Medicine was pointed out. All these are invaluable experience for the development and progress of this course.

Objective:To study the clinical features, experiences of diagnosis and treatment, and treatment process of ovarian nonspecific steroid cell tumor. Methods:The clinical materials of one case of ovarian nonspecific steroid cell tumor were retrospectively analyzed,and the related literaturels were reviewed. Results:The patient displayed amenorrhea and masculine characteristics.Preoperative ultrasonography demonstrated the solid tumor of 53 mm ×39 mm on the right ovary,consideration for the right side of ovarian malignant tumor,and laparotomy was performed.The pathologic results showed that the tumor cells were arranged in nests,and the cytoplasm was bright or eosinophilic, and the nucleus were round or oval with nucleolus.The immunohistochemical staining results revealed that calretinin,vimentin and inhibin were positive in the tumor cells.The patient was diagnosed with ovarian nonspecific steroid cell tumor.The postoperative follow-up of 3 months was performed,and there was no recurrence.Conclusion:The diagnosis of ovarian nonspecific steroid cell tumor should be combined with the clinical manifestation and pathologic results,and operion is the main treatment method.

Objective To explore the expression of 10 kDa interferon-gamma-induced protein(IP-10)in pathological scar and its role in the pathogenesis of pathological scar.Methods Imrnunohistochemistry was performed to detect the expression and distribution of IP-10 in 28 patients with keloid(group K),34 patients with hypertrophic scar(group HS),and 20 normal controls(group N).The data were collected and analyzed statistically.Results The expression of IP-10 was significantly higher in groups K and HS than in group N(P＜0.01),but no significant difference in the expression of IP-10 was found between groups K and HS.Conclusion IP-10 may enhance the formation of pathological scar by attracting T lymphocytes and inducing immune/inflammatory response.

Objective To understand the research status and development tendency of domestic geriatrics.Methods To analyze all the key words in the academic articles from five representative Chinese journals of geriatrics from 2009 to 2013 through key words frequency analysis.Results From 2009 to 2013,the 55212 key words in 15314 articles were analyzed.The percentages of the articles indexing 3,4 and 5 keywords were 39.3％ (6012/15314),33.3％ (5092/15314) and 13.9％(2123/15314),respectively.There were 45 high-frequency keywords,among which 17 key words (37.8％) were in the top 30 every year.The main research object of geriatrics was Aged,the main research contents were common diseases in the elderly,including Diabetes Mellitus,Coronary Artery Disease,Alzheimer's Disease,Hypertension,Cerebral Infarction,Cognition Disorders and etc.The Risk Factors,Therapeutics and Prognosis of these common diseases were always explored.Co-words analysis showed that there were 51 pairs of key words with a frequency more than or equal to 20.Conclusions The hot-spot of geriatric research in our country is relatively concentrated.We should pay attention to body disease,and focus on the mental health problems in the elderly.

Objective To investigate the characteristics of the author groups in 《Chinese Journal of Geriatrics》,in order to provide references for the future construction and development of the author ranks.Methods Bibliometric method was used to analyze the quantity of papers,region distributions,core authors and cooperative rate in 《Chinese Journal of Geriatrics》 from 2009 to 2013.Results The total amount of papers published in 《Chinese Journal of Geriatrics》》 from 2009 to 2013 was 1636,involving 31 provinces,autonomous regions,municipalities and administrative region.Among these,Beijing,Zhejiang,Tianjin and Jiangsu were the 3 top contributing regions,accounting for 54.0 percent (884/1636 papers).The 1636 papers were contributed by 1435 authors (first authors),of whom 1275 authors published only one paper,accounting for 87.7％ (1275/1435),and their papers accounted for 77.9％ of the total published papers (1275 /1636).27 authors had high yield of 3 or more papers published and deep influence,and they published 95 papers (5.8％).The degree of cooperation was 4.6 (7599 /1636),and the cooperation rate was 93.8％ (1534/1636) within the five years.Conclusions 《Chinese Journal of Geriatrics》is quite influential and attractive in the fields of geriatrics,and a good cooperative relationship is displayed between different authors and authors' institutions.

Adult ; Female ; Humans ; Male ; Occupational Diseases ; Organometallic Compounds ; poisoning