Objective To study the nursing features and effects of using insulin pump in gestational diabetes , and to grope for pregnant women during pregnancy care and education mode , how to make the gestational diabetes pregnant women safely through pregnancy to ensure that maternal and child health.Methods A retrospective analysis were done on 47 cases of gestational diabetes pregnant which treated by insulin pump from January 2004 to January 2009, reinforced therapy of using insulin pump and comprehensive care measures including mental nursing, diet therapy, appropriate physical training, skill nursing, healthy education and so on were taken.Results The blood glucose of all patients were well controlled, there were no complication of hypoglycemia reaction, hypoglycemia reaction, diabetic hyperosmolar coma, diabetic ketoacidosis and fetal distress in uterus.Conclusion It is considerable significance that perfect pregnancy care, active and effective nursing inter-vention for reducing infant and maternal complications and ensuring maternal and child health .

OBJECTIVE:To select an optimal extraction technique of Whitmania pigra whiman.METHODS:The af?fecting factors such as variety of solvent,temperature,time,the amount of solvent and the frequency of the extraction were studied on the basis of protein content in the hirudo extract and activated partial thromboplastin time(APTT).RESULTS:The optimum extraction result was obtained in4%NaCl solvent of10-fold as much as the medicine with3times of extraction at60℃for6h((3h+2h+1h).CONCLUSION:The present technique is simple,scientific and practicable.

Central exudative chorioretinopathy( CEC),also known as idiopathic choroidal neovascularization (ICN),was more common in middle-aged,appearing the isolated macular choroidal neovascularization lesions ( CNV ).CNV can cause macular hemorrhage,exudativeing and scarring and therefore affect the patient' s central vision.The etiology of CEC is below understanding,and the treatment aimed at CNV.The clinical management of CEC include photodynamic therapy ( PDT),the administration of antibody of vascular epithelial growth factor ( VEGF ),adrenal glucocorticoid drug,combined therapy,transpupillary thermotherapy (TTT),laser photocoagulation,ratiotherapy,surgery,Chinese traditional medicine and gene therapy.The various treating approaches and their mechanisms were reviewed.

CCN1 is a novel extracellular matrix-associated signaling protein which possesses 381 amino-acid residues to compose 4 distinct structural modules with 38 conserved cysteine residues.This protein has a variety of properties in cardiovascular system,affecting the cellular behaviors such as differentiation,proliferation and migration of vascular endothelial cells,smooth muscle cells and cardiac myocytes,that suggested an essential roles of CCN1 in angiogensis,vascular injury,cardiac development and myocardial infarction.

OBJECTIVE To study air disinfection methods in unremitting operating room,we compared effect of using trioxide disinfector(used in operating room "A") with YKX/G100-type medical air disinfection and purification machine(used in operating room "B") in disinfecting air inside unremitting operating room.METHODS To observe the killing effect on air natural bacteria of the two methods,we used natural sedimentation monitoring the different stages sampling before and after sterilization and at the beginning stage of the unremitting operation.RESULTS Both the two methods could achieve the air natural bacteria eradication rate above 85%.The air bacteria colony number obviously upgraded after the beginning of unremitting operation in operating rooms "A";but in operating rooms "B",the number fell-off slowly.CONCLUSIONS The medical air disinfection and purification machine can shorten the interval of operations,it is the better approach of continuous air disinfection in solving the unremitting operating room with personnel existence.

Objective To analyze the distribution and drug sensitivity of pathogenic bacteria in urinary tract infection,and to provide evidences for rational use of antibiotics in clinic.Methods The data from 3 677 midstream urine specimens for bacterial culture were retrospectively analyzed.VITEK-2Compact was used to identify bacteria and test drag sensitivity.And WHONETS.6 was used to statistically analyze the data.Results Of 649 strains of pathogenic bacteria from urinary tract infection patients,there were 439 strains of gram-negative bacteria,accounted for 67.6％,among which there were 301 (46.4％) strains of Escherichia coli,and 74 (11.4％) strains of Klebsiella pneumoniae;there were 121 strains of gram-positive cocci,accounted for 18.7％,among which there were 97(14.9％) strains of Enterococcus,and 22 (3.4％) strains of Staphylococcus;there were 89 strains of fungi,accounted for 13.7％.According to drug susceptibility,the sensitive rates of Escherichia coli and Klebsiella pneumoniae to imipenem,cefotetan,piporacillin-tazobactam and amikacin were all over 87.0％.The drug sensitivity of Enterococcus to vancomycin and linezolid were both 100.0％.As to drug resistance to other drags,Enterococcus faecium was higher than Enterococcus faecalis.Conclusion Escherichia coli is the primary pathogenic bacteria of urinary tract infection.Every bacteria strain has a high drug resistance.In clinic,hospital should perform urine bacterial culture and drug sensitivity tests timely,and use antibiotics rationally in order to reduce the production and growth of drug-resistant bacteria.

BACKGROUND: Officers and intellectuals are bearing heavy government affairs and tasks of teaching and scientific research. It is practically important to acknowledge and master their body constitution, which can help to instruct them to scientifically build their bodies.OBJECTIVE: To investigate the body function and shape as well as body constitution of scientific researchers and officers in Handan, and analyze the existing problems and bring out the settlement.DESIGN: Cross-sectional study.SETTING: Hebei Provincial Committee Party School.PARTICIPANTS: A total of 499 subjects, aged 20-59 years, including238 males and 261 females were selected from government officers, university teachers and scientific researchers of institute and aeademy by using stratified and cluster random sampling. Subjects aged 20-39 were divided into adult group A (50.5%), and those with the age ranged 40-59 were taken as adult group B (49.5%).METHODS: All subjects fulfilled the questionnaire (including whether they had hospitalized history, and the smoking condition, exercise condition, reasons why did not participate in the sports, sports items that patients took part in, the place they conducted athletic activities, time of each exercise and exercise times per week etc.) and were measured of the body constitution.MAIN OUTCOME MEASURES: ①Indexes of body function and shape,including body height, body mass, chest circumference, waistline, hip circumference and skinfold at all parts of body as well as the pulse in quiet state, systolic blood pressure (SBP), diastolic blood pressure (DBP) and lung capacity etc. ②Indexes of body constitution, including grasp force,bend-ahead in sitting, stand up on one leg with eyes closed, choice reaction time simple reaction time, back strength, 10 m×4 shuttle run, and pushup (male)/sit-up (female) etc. The results of test were scaled according to the Report of Monitoring of Chinese Adult Constitution, edited by the State Physical Cultural Administration. Those with the score greater than 17 points passed, while those less than 17 points failed.③The relationship between status quo of body constitution and life style.RESULTS: A total of 499 subjects were involved in the analysis of results.①With the age increasing, the body mass in males and females were increased with circumferences being enlarged and subcutaneous fat increased, and the shape was in horizontal development. The body function in females with the age ranged 20-40 were relatively stable, and began to descend at 40. The body function in adult males descended gradually and stably with the descending speed lower than in females. The force, bursting strength of lower limbs, position sense, coordination of sight and proprioceptive sense, speed in motion and response etc. Of adult males were better than males, while the extensibility and tenacity of joint, muscle and tendon were superior in females than in males. All indexes of constitution in males aged 20-40 were better, while the tenacity and speed in motion and response of males older than 40 began to decay rapidly. ②The pass rate in males of adult group A was 87.5% and was 87.3% in females, while that in males of adult group B was 80.2% and was 74.8% in females. ③The pass rate in populations with exercise custom was greatly higher than in those without it, while the proportion of exercise people accounted little in the subjects. It accounted for 40.7% in males of adult group A and for 28.6% in females, and it accounted for 37.3% in males of adult group B, and for 31.6% in females. ④Body constitution in people who never smoke and occasionally smoke were better than in those often smoke. The pass rate in people who had been hospitalized was a little lower. ⑤The pass rate in subjects who exercised three or four times each week was much higher,and it was the highest in subjects exercised 30-60 minutes each time.CONCLUSION: ①The constitution in population older than 40 is significantly worse and worse. ②Sports activities can remarkably promote the body constitution.③Smoking has obvious side effects on body constitution.④It can reinforce the body constitution by doing sports activity for 30-60 minutes and 3 or 4 times each week.

A retrospective survey wag performed among medical staff in a hospital during 2006-2008 with physical examinations and reviews of medical records.Nonalcoholic fatty liver disease(NAFLD)related factors were compared and analyzed for them.Overall detection rate of NAFLD was 13.9%(230/1655)in 2006 and 18.9%(344/1817)in 2008,with statistically significant difference(χ2=15.549,P＜0. 01 ). Among people surveyed over 30 years old, detection rate of NAFLD was 9.4%, 17. 8% and 21.7% for those aged 30 -39, 40 -49 and 50 years and over, respectively in 2006, while 14. 4%, 28. 2% and 30. 5% , respectively in 2008. Detection rate presented a increasing trend in those of younger age. Relative risk for fatty liver was 1. 859 for those with obesity and overweight. Prevalence of NAFLD in medical staff increases year by year. Medical staff should attend for their own health and take measures to prevent them from its potential risk factors and pay more attention to behavioral intervention for NAFLD.

Objective To observe autonomic nerve function damage in diabetic patients with gastrointestinal symptoms. Methods Twenty-four patients of diabetes mellitus (DM) with gastrointestinal symptoms, as well as 20 cases of DM without gastrointestinal symptoms and 17 health volunteers were recruited from the clinic of gastroenterology, Jishuitan Hospital, Beijing during December 2008 to May 2009, and standard cardiovascular reflex test was performed for all of them to determine their functions of the autonomic nerve. Results Respiratory rate (an indicator of parasympathetic nerve function) was ( 14 ± 5 ) times per minute in patients of DM without dyspepsia, obviously lower than that in healthy controls [(20±10) times per minute], and that in patients of DM with dyspepsia was (9 ±6) times per minute, obviously lower than that in healthy controls and asymptomatic ones ( P ＜ 0. 05 ). Scores of five indicators of the autonomic nerve functions, and the sympathetic, parasympathetic nerve and overall autonomic nerve functions were significantly higher in patients of DM with gastrointestinal symptoms than those in the patients without dyspepsia and healthy controls. Abnormality rate of autonomic nerve functions was 96 percent (23/24) in the patients with dyspepsia, 58 percent (14/24) in those definitely and seriously involved, and five percent (1/20) in those without dyspepsia. Conclusions Autonomic neuropathy exists in most diabetic patients with dyspepsia, both sympathetic and parasympathetic nerve involved. Impairment of parasympathetic nerve function occurs earlier than that of sympathetic nerve in patients of DM.

Objective To analyze the clinical value and safety of capsule endoscopy in the digestive tract diseases.Methods 55 cases of inpatients or outpatients were given the capsule endoscopy examination.The positive detection rate and safety were observed.Results The positive detection rate was 87.3％,the diagnostic rate was 50.9％.Capsule retention in the body happened in 2 cases (1 case of small intestine space-occupying lesions,decided to take the operation,another 1 case got Crohn's disease,intestinal incomplete obstruction),the occurrence rate was 1.5％.Conclusion The capsule endoscopy make up some shortcomings of the traditional gastrointestinal endoscope,but also show some drawbacks,so improving performance of instrument of the capsule endoscopy,expanding the scope of application of capsule endoscopy will be the development direction of the capsule endoscopy in the future.