1.Effect of acetamide on cardiac troponin I of rats with tetramine poisoning.
Yu-Jun MENG ; Jian-Ling SU ; Hong-Shun ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(11):668-669
Acetamides
;
pharmacology
;
Animals
;
Bridged-Ring Compounds
;
poisoning
;
Disease Models, Animal
;
Female
;
Male
;
Rats
;
Rats, Sprague-Dawley
;
Troponin I
;
blood
2.Analysis of the Volatile Oils in the Flowerbuds of Panax quinquefolium L.
Xiangying MENG ; Xianggao LI ; Hong ZHANG ; Yu HAN
Chinese Journal of Analytical Chemistry 2001;29(5):542-545
Thirty nine compounds in the volatile oils of the flowerbuds of Panax quinquefolium L.cultivated in China were isolated and identified with gas chromatography/mass spectre metry. To our great surprise,β-famensene,a sesquiterpene compound of them,alone account for 48.67% of the total volatile oils contents. This experimental result was contrasted with the volatile oils components of the different parts of Panax quinquefolium L.and Panax ginseng,anidentical genus plant,on chemical components and relative quantities.It was discovered that the only one common component is β-famensene in them and it is the highest value in determined relative contents. Above result provides scientific basis for biological synthesis of triterpenoid saponins.
4.Two lines tension relaxing correction for deviation of nasal septum.
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2013;48(12):1037-1038
Adolescent
;
Adult
;
Aged
;
Female
;
Humans
;
Male
;
Middle Aged
;
Nasal Septum
;
abnormalities
;
surgery
;
Rhinoplasty
;
methods
;
Young Adult
5.Analysis and prophylactico-therapeutic measures of the failure cause of replantation of severed finger
Qi-Ming CHEN ; Lin-Quan YU ; Hong MENG ; Xiao-Fang HONG ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
Objective To find out the causes of the failure of the replanted finger and to increase the survival rate of replantation.Methods The trauma,operation condition and nursing care after operation of the 24 failure cas- es of 31 replantation of severed fingers that have been treated in this hospital from January 1999 to December 2006 were retrospectively analyzed.Results Of the 31 necrotic fingers,there were 21 necrotic fingers caused by untimely treatment of vascular articulo,7 by infection,1 by smoking and 2 by uncooperative treatment because of out-of-bed activity.There were 9 replantation of fingers loss of blood supply in one day,12 fingers from one day to three days, 8 fingers from four days to seven days,2 fingers more than nine days.Conclusion The operation indication should be strictly mastered.There should be a complete debridement and haemostasis during the operation,the quality of vascular anastomose should be improved and the pressure of the anastomosing vascular should be avoided.Strict ob- servation after operation,intensive nursing and timely treatment of vascular articulo are the key factors for improving the survival rate of replantation of severed finger.
6.Cosmetic medicine of a bio-psycho-social model:theoretical analysis and designs of a clinical work system
Meng YU ; Jianning LI ; Hong TANG ; Wei YU ; Bailin PAN ; Hanbin SONG ; Lan ZHOU
Chinese Journal of Medical Aesthetics and Cosmetology 2011;17(2):132-135
Objective To establish a cosmetic medicine bio-psycho-social model and its theory frame and a new clinical work system. Methods The clinical observation and clustering analysis were used in this study, which based on the modern medicine patterns to carry on the logical proof, theory derivation and systematic design. Results The bio-psycho-social model of cosmetic me dicine with combination of the theory and practice was established, including its concept, theory constitution and clinical work system. Conclusion The bio-psycho-social model of cosmetic medicine can most scientifically and comprehensively explain this discipline rule and clinical work, and it will bring the profound influence on the development of the theory and practice in cosmetic medicine.
7.Effect of water temperature, stocking density and feeding cycle on growth of juvenile Poecilobdella manillensis.
Bo-xing CHENG ; Fei LIU ; Qiao-sheng GUO ; Hong-zhuan SHI ; Meng-meng LI ; Yu-xi LU
China Journal of Chinese Materia Medica 2015;40(6):1071-1074
The effect of water temperature, stocking density and feeding cycle on the growth of Poecilobdella manillensis juvenile was conducted P. manillensis was conducted respectively under different conditions: water temperatures(18, 22, 26, 30,34, 38 degrees C and CT), stocking density (75, 125, 200, 275, 350 individual/L) and feeding cycle(2, 4, 6, 8, 12, 16 d). After 30 days, survival rate, weight gain rate, specific growth rate were measured. There was a significant correlation between water temperature and specific growth rate (γ = -0.066x2 + 3.543 1x -38.09, R2 = 0.837 9). Based on the regression equation, the specific growth rate of P. manillensis achieved the maximum (9.461 4) at 26.84 degrees C. And the most optimal water temperature was 26-30 degrees C. Meanwhile, the survival rates of P. manillensis was 0 at 38 degrees C in 3 d. There was significant negative correlation between density and specific growth rate (γ = -0.005 7x + 9.197 3, R2 = 0.998 3) and between feeding cycle and specific growth rate (γ = -0.468 2x + 10.574, R2 = 0.998 8).
Animals
;
Annelida
;
growth & development
;
physiology
;
Body Size
;
Feeding Behavior
;
Temperature
;
Water
;
chemistry
9.Dynamic changes of cardiac structure and function in mice with abdominal aortic constriction.
Mao-Lin ZANG ; Meng-di YU ; Zhong-Hua CHEN ; Meng-Qi HUANG ; Peng LUO ; Hong-Kun FAN ; Chun YANG
Chinese Journal of Applied Physiology 2021;37(5):479-482
Animals
;
Cardiomegaly
;
Constriction
;
Heart
;
Mice
10.The role of ADME evaluation in translation research of innovative drug.
Yao LIU ; Lan HONG ; Lushan YU ; Huidi JIANG ; Jianzhong CHEN ; Qin MENG ; Shuqing CHEN ; Su ZENG
Acta Pharmaceutica Sinica 2011;46(1):19-29
New Chemical Entities (NCEs) development is a systematic long-term project that involves multiple disciplines. The translation research will help to build an advanced R&D system from the basic laboratory research, preclinical studies and clinical evaluation to clinical application of drug, for the purpose of shortening the R&D cycle and accelerate the launch of new drugs. In new drug R&D and its clinical application, drug disposition (absorption, distribution, metabolism, excretion, ADME) properties are important criteria for assessing drug-likeness of candidates. ADME evaluation of NCEs plays an important role in the translation research throughout innovative drug R&D process. Therefore, ADME evaluation at the early stage of drug design and development will be helpful to improve the success rate and reduce costs, and further access to safe, effective drugs.