1.Production and application of improvement of dyeing on syphilis quality control material
Jin YU ; Ru YANG ; Rong FU ; Hao BI
International Journal of Laboratory Medicine 2017;38(1):18-20
Objective The color of the syphilis quality control material adopted by most detection institutes was the same with the detected serum sample and they were all colorless,transparent or light yellow.There were cases of wrong adding,missing adding or insufficient adding due to the color of quality control materials which was hard to distinguish with naked eyes.To avoid this phenomenon,a new method was established for the distinction of quality control materials.Methods A new method of syphilis quality control materials that had been improved three concentrations control materials:0.125,0.250 and 0.500 NCU/mL.The syphilis diagnostic kit that was created by Shanghai Kehua and Xiamen Yingke was adopted to conduct detection and compare results.Results The difference between stained quality control material and unstained quality control materials had no statistical significance (P>0.05).Two different reagents were used to detect quality control materials of different concentration for 20 times and the CV were 11.7 %-13.4% and 9.3 %-12.9 % respectively.Two different reagents were used to detect quality control materials of different concentration for 30 days and the CV range were 10.1 %-13.4 % and 8.08 %-12.8 %.Conclusion Citric yellow staining does not influence the properties of syphilis control materials and it can be used stably for a long time.It is suitable for clinical lab application and promotion.
2.Experience of YU Ren-cun in Treating Cough and Asthma of Lung Cancer
Qi FU ; Hao WANG ; Dong HAN ; Jie YU
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(10):102-104
Professor YU Ren-cun believes that the responsibility of cough and asthma of lung cancer patients not only lies in the lungs, but also relates with spleen, kidney, heart and liver. Treatment should focus on the whole body and overall conditioning. Syndrome can be divided into 4 types: qi deficiency with phlegm resistance, yin deficiency with toxic heat, qi stagnation with blood stasis, and lung and kidney deficiency. Clinical treatment should pay attention to the combination of disease and syndrome, which can achieve satisfactory efficacy.
3.Large sessile colorectal polyps underwent endoscopic mucosal resection
Enda YU ; Ronggui MENG ; Honglian XU ; Miao LIN ; Chuangang FU ; Hao WAHG ; Hantao WAHG ; Liqiang HAO
Chinese Journal of Digestive Endoscopy 1996;0(05):-
1. 5 cm) sessile colorectal polyps referred for EMR. After submucosal injection of epinephrine, either en bloc or piecemeal snare polypectomy were performed. All resected specimens were retrieved for pathologic study. Follow-up colonoscopy was performed in all patients after EMR. Results All 157 polyps were removed completely. All lesions are larger than 1. 5cm, but 3 less than 1 cm on the submucosa of rectum. The largest one is 13 cm X 12 cm. No complication occurred. Histopathologic assessment of the resection specimens revealed the following: adenoma, 123; dysplasia, 80; mucosal carcinoma, 11; hyperplastic polyps, 20; rectal carcinoid, 3. Two patients who had rectal adenoma that was larger than 7cm recurrence happened at the resection site after 1 and 3 months follow-up respectively, than removed completely by hot biopsy forceps showed hyperplastic and villous adenoma on pathological study. No more residual tumor was detected for 6-12 months. Conclusion EMR with an intensive follow-up program is a safe and effective treatment for large sessile colorectal polyps and mucosal carcinoma.
4.A study on the number of lymph node harvested after radical resection of invasive rectal carcinoma
Hao WANG ; Chuangang FU ; Fuao CAO ; Haifeng GONG ; Enda YU ; Wei ZHANG ; Lianjie LIU ; Liqiang HAO ; Hantao WANG ; Ronggui MENG
Chinese Journal of General Surgery 2009;24(2):92-95
Objective To evaluate the number of lymph node harvested during radical resection of invasive rectal carcinoma(stage Ⅰ toⅢ).Methods From January 2000 to June 2008,the pathological data of colorectal carcinoma patients who were operated on were retrospectively reviewed.Exclusion criteria included recurrent colorectal tumor,Tis tumor,R1 or R2 resection,tumor resection transanally or endoscopically,synchronous diseases affecting the surgical procedure for the reetal cancer(familial adenomatous polyposis.synchronous coloreetal carcinoma)and rectal cancer receiving perioperative neoadiuvant chemoradiation.Statistical analysis was performed using Mann-Whitney Test and Chi-Square Test (SPSS 15.0).Results were expressed as mean±SEM.Results A total of 2282 patients were identified.including 1216 cases in the rectal carcinoma group and 1066 cases in the colon carcinoma group.There were no significant difference in gender(719/1216 vs.593/1066,P=0.092)and overall TNM stage (P=0.067)between the two groups.But patients of rectal cancer were younger(58.6±0.4 vs.62.0±0.4.P=0.000).The lymph node retrieval in the rectal carcinoma group was significantly less than that of colon carcinoma group(9.4±0.1 vs.10.5±0.1,P=0.000).There were significantly less rectal cancer patients with a 1ymph node harvest equal to or more than 12 nodes(P=0.000).Patients in the low rectal cancer group(≤7 cm from the anal verge.n=834)had less lymph nodes harvested than the mid-high rectal cancer group(>7 am and≤15 cm from the anal verge.n=382)(9.2±0.1 vs.9.9±0.2,P=0.009).Conclusion The lymph node harvest in the rectal carcinoma group was significantly less than that in the colon carcinoma group.A new standard may be necessary to define the adequate number of lymph nodes for rectal cancer.
5.Clinical and pathologic prognostic factors affecting local recurrence and overall survival in 1 166 rectal cancer resection patients
Qizhi LIU ; Zheng LOU ; Xianhua GAO ; Ronggui MENG ; Chuangang FU ; Enda YU ; Liqiang HAO ; Hantao WANG ; Hao WANG ; Wei ZHANG
Chinese Journal of General Surgery 2017;32(1):5-8
Objective To explore the clinicopathologic factors impacting recurrence and survival in rectal cancer patients after radical resection.Methods Clinicopathologic data of 1 166 patients with rectal cancer in Changhai Hospital,were recruited between 2005 and 2010.Kaplan-Meier analysis and the logrank test were used to evaluate the effects of the pathology on patients' survival.Cox regression model was used to assess independent factors associated with clinical prognosis.Results The 1,3,5-year overall survival rates were 94.3%,81.2% and 76.5%,median survival time was 53 months.328 patients had recurrence and metastases,with a median recurrence time of 18 months.The independent prognostic factors for overall survival time were CEA,CA19-9,tumor distance to dentate line,surgical modality,radical operation,tumor invasion,tumor differentiation,lymph node metastasis and postoperative treatment.Surgical treatment,radical operation or not,tumor invasion and lymph node metastasis were statistically significant associated with tumor recurrence and metastases.Conclusions The important factors inffuencing the prognosis of rectal cancer patients were CEA,CA19-9,tumor distance to dentate line,surgical modality,radial operation,tumor in vasion,tumor differentiation,lymph node metastasis,and post operative treatment.
6.Effect of integrated traditional Chinese and Western medicine therapy on progression of acute renal failure in patients with chronic renal insufficiency: a short-term clinical study
Peng FU ; Guang YU ; Xueqiang HUANG ; Jing XU ; Xiaobin MEI ; Hao WU ; Weijie YUAN
Journal of Integrative Medicine 2004;2(6):429-31
OBJECTIVE: To evaluate the effect of integrated traditional Chinese and Western medicine therapy on the progression of acute renal failure in patients with chronic renal insufficiency. METHODS: Thirty-two patients with chronic renal insufficiency developed acute renal failure recently were treated with Chinese herbs and western drugs intravenously and clysterizing of Chinese herbs liquid for 30 minutes, and the treatment course was 14 days. Assessment of liver and renal function, blood routine, electrolytes and endogenous creatinine clearance rate (Ccr) was performed before and 2 weeks after the treatment. RESULTS: The levels of hemoglobin (HB), white blood cell count (WBC) and serum electrolytes showed no significant changes after the treatment. The levels of blood urea nitrogen (BUN) and serum creatinine (SCr) decreased, while the level of Ccr increased significantly (P<0.05) after the treatment. The total effective rate was 65.6%. CONCLUSION: The integrated traditional Chinese and Western medicine therapy can effectively delay the deterioration of renal function in patients with chronic renal insufficiency accompanied by acute renal failure.
7.A systematic review for donor kidneys after resection of small renal cancer
Nengwang YU ; Shuai FU ; Xiaofei WANG ; Junwen HAO ; Aimin ZHANG ; Xiangtie LI
Chinese Journal of Organ Transplantation 2013;34(12):733-736
Objective To review the literature and synthesize current evidence on the use of kidneys with small renal cancer as donor kidneys.Method To locate eligible studies,four bibliographic databases including PubMed,Embase,Cochrane Library and ClinicalTrials.gov were screened,while key informants were collected and bibliographies of included studies were scrutinised.Two reviewers independently assessed studies for inclusion,extracted data.Data were synthesised as a narrative review.Results 1680 articles were found while eventually 15 studies were selected for this systematic review.All of the 15 included studies were case reports or case series.Totally 96 documented cases of donor kidneys after resection of small renal cancer were transplanted and no definite recurrence happened.Conclusion It is suggested from current limited evidence that cancer recurrence rate of allotransplanting kidney after resection of SRC was relatively low,thus it deserved much more well-designed clinical trials and clinical use.
8.Mortality in the aged patients with hip fractures treated by operations
Yu DANG ; Jing ZHOU ; Zhongguo FU ; Dianyin ZHANG ; Hao LU ; Tianbin WANG ; Hailin XU ; Baoguo JIANG
Chinese Journal of Orthopaedic Trauma 2009;11(7):642-644
Objective To analyze the mortality in the aged patients with hip fractures who have been treated by operations. Methods We collected the clinical data of 349 aged patients (60 to 98 years old) with hip fracture who had been treated by operations from March 1999 to January 2008 in our hospital. Their overall mortality and one-year mortality were analyzed to find the causes for death. Results Thirty-one cases died and the overall mortality was 8.9% (31/349). Nineteen patients died within one year and the one-year mortality was 5.4% (19/349). Three patients died in hospital after surgery, 28 patients died in the follow-up period. Cardiac event, pulmonary dysfunction, cancer, cerebral vascular disease, hepatic cirrhosis, multiple organs dysfunction and infection were sequentially the major causes for death. Statistical results showed the factors which had definitely influenced the mortality were age and sex. Patients treated with proximal femoral nail anti-rotation (PFNA) had the lower mortality than with proximal femoral nail (PFN). Conclusions Operations can lead to a low mortality for aged patients with hip fractures. Ad-equate preparation and mini-invasive surgery can reduce the mortality.
9.The diagnosis and treatment of early postoperative internal hernia
Hao WANG ; Yongqi SHAN ; Xiujun LIAO ; Ronggui MENG ; Chuangang FU ; Enda YU ; Wei ZHANG ; Lianjie HU
Chinese Journal of General Surgery 2008;23(5):350-352
Objective To investigate the clinical manifestations of early postoperative internal hernia. Methods Patients who were diagnosed with early postoperative small bowel obstruction(EPSBO)within 30 days after operation and underwent laparotomy between 1994 and 2006 were included for study.Clinical and radiological findings were analyzed. Results Totally 38 EPSBO patients were identined.among those,9 patients(23.7%)had an internal hera ag the cause of the howel obstruction.Other causes included intestinal adhesions in 27 patients(71.1%),gallstone ileus in 1 patient(2.6%)and stoma obstruction in 1 patient(2.6%).In the internal hernia group,6 cases were male and 3 cases were female witIl a mean age of 53.6 years.The mean time from the primary operation to symptom development was 7.8 d(range,2~17 d)and the mean time of conservative treatment Was 3.4 d(range,1~8 d).The main clinical features included:complete mechanical obstruction with symptoms rapidly progressing and early bowel strangulation.Specific radiologic abnormalities misht be identified,especially by contrast-enhanced CT.In this series,intestinal strangulation was found in 6 patients with bowel necrosis in 4 eases,necessitating howel resection in 5 patients.Wound infection developed in one cage and there was no perioperative death.Conclusion Internal hernia can occur early postoperatively and it bears a high risk of strangulation and bowel necrosis.Prompt operative intervention should be carried out in highly suspicious patients in order to avoid complications and achieve good outcome.
10.A cystic vestibular schwannoma with a fluid-fluid level.
Hui FU ; Shu-Yu HAO ; Gui-Jun JIA ; Jun-Ting ZHANG ; Li-Wei ZHANG
Chinese Medical Journal 2012;125(21):3920-3920