1.Effect of Yupingfeng Powder on Immune Function in Cough-variant Asthma Patients at Remission Stage
Yu ZHANG ; Zhongde ZHANG ; Xi ZHANG
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(06):-
Objective To observe the effect of Yupingfeng Powder(YP) on IgE level and T lymphocyte subpopulations of CD4+ and CD8+ in cough-variant asthma patients at remission stage.Methods Seventy-four cough-variant asthma(CVA) patients at remission stage were randomized into two groups.The treatment group(N=36) received oral use of YP and the control group(N=38) received oral use of placebo,the treatment lasting 8 weeks.The changes of serum IgE level and T lymphocyte subpopulations of CD4+ and CD8+ were observed before and after treatment.Results After treatment,serum IgE level and CD4+ percentage were decreased,CD8+ percentage increased,and CD4+/CD8+ decreased in the treatment group(P0.05),but were significant between the control group and the treatment group after treatment(P
2.ADVANCES ON ALGICIDAL SUBSTANCES PRODUCED BY ALGICIDAL BACTERIA
Yong ZHANG ; Yu XI ; Gang WU ;
Microbiology 1992;0(01):-
In recent years,more and more researchers have realized the possibility that algicidal bacteria could be a useful tool in reducing the impact of harmful algae blooms. In this review, the ecological roles of algicidal substances was briefly discussed, then special emphasis placed on the categories and extract methods of algicidal substances which have been reported. Some ideas for the further studies on algicidal substances were also proposed.
4.Clinical analysis of elderly patients with osteoporotic hip fractures
Chinese Journal of General Practitioners 2017;16(8):618-620
Clinical data of 448 patients aged ≥60 years with osteoporotic hip fractures admitted in Shanghai Huashan Hospital between January 2010 and December 2014 were retrospectively analyzed.Among 448 cases,there were 143 males and 305 females;196 cases aged 80-89 years (43.8%) and 137 cases aged 70-79 years (30.6%);304 cases of femoral neck fracture (67.9%) and 144 cases of intertrochanteric femoral fracture (32.1%);the fractures caused by fall in 328 cases (73.2%) and comorbidity with hypertension and diabetes mellitus in 415 cases (92.6%).Two hundred and sixty eight patients were followed up for 2 years,among whom re-fractures occurred in 17 cases.The study indicates that health education is important for prevention of osteoporotic fractures in elderly people.
5.Re-recognition and thinking of membrane anatomy.
Chinese Journal of Gastrointestinal Surgery 2021;24(12):1119-1121
6.Garcinol inhibits proteasome and suppresses tumor growth via targeting RPN6
Ying YU ; Xi-song KE ; Xue ZHANG
Acta Pharmaceutica Sinica 2025;60(2):408-416
Garcinol, a benzenetriol compound extracted from
7.Correlation of Lactate Dehydrogenase and Neuron?specific Enolase with Prognosis of Extensive Small Cell Lung Cancer
Xi YU ; Xi YU ; Binbin ZHANG ; Bijie YANG ; Zhe ZHANG ; Mingxia MA ; Jiayun ZOU ; Mingfang ZHAO
Journal of China Medical University 2017;46(5):425-428
Objective To determine whether neuron?specific enolase(NSE)affects the prognosis of extensive small cell lung cancer by analyz?ing the association between NSE before treatment and disease progression and overall survival of patients. Methods This study retrospectively an?alyzed 83 inpatients in the medical oncology department of the First Affiliated Hospital of China Medical University from March 2008 to September 2014. The Kaplan?Meier method and Cox proportional hazards models were used to analyze relevant factors affecting the prognosis of extensive small cell lung cancer;statistical significance was determined for a P value less than 0.05. Results The lactate dehydrogenase(LDH)level be?fore treatment was significantly associated with the progression?free survival(PFS)(P=0.001)and overall survival(OS)(P=0.036). The NSE level before treatment was also significantly associated with the PFS(P=0.007)and OS(P=0.013). Conclusion LDH and NSE affect progno?sis and survival of patients with extensive small cell lung cancer.
8.Correlation of Hemoglobin and Bilirubin with Prognosis of Extensive Stage Small Cell Lung Cancer
Xi YU ; Binbin ZHANG ; Xi YU ; Bijie YANG ; Zhe ZHANG ; Mingxia MA ; Jiayun ZOU ; Mingfang ZHAO
Journal of China Medical University 2017;46(2):112-115
Objective To explore the factors that affect the prognosis of extensive small cell lung cancer by analyzing the association between lab-oratory indicators before treatment of extensive small cell lung cancer patients and the initial evaluation results with disease progression and overall survival. Methods This study retrospectively analyzed 96 cases of hospitalized patients in the medical oncology department of The First Hospital of China Medical University from March 2008 to September 2014. Kaplan-Meier method and Cox proportional hazards models were adopted to ana-lyze the relevant factors affecting the prognosis of extensive small cell lung cancer. P<0.05 was considered statistically significant. Results There was no obvious correlation between HB level before treatment with PFS of patients(P=0.179),but there was obvious significant correlation be-tween HB level and OS of patients(P=0.041). Our results showed that the TBIL level of patients before chemotherapy was significantly associated with the PFS(P=0.039)and OS(P=0.026)of patients. Conclusion HB and TBIL levels are the influencing factors that affect the prognosis and survival of patients with extensive small cell lung cancer.
9.Kinetics of Fed-batch Cultivation on Recombinant Escherichia coli Containing Human-like-Collagen cDNA
Yu MI ; Xiu-Fu HUA ; Dai-Di FAN ; Xi ZHANG ;
China Biotechnology 2006;0(04):-
The kinetics of batch and fed-batch cultures of recombinant Escherichia coli to produce humanlike collagen were investigated. Through examining the density of substrate and the amount of mushrooms and the density of products during the process of fermenting, a set of kinetic models are set up. The influence of cell without plasmid was considered. The results show that the kinetic model may well simulate the fermenting process.