1.Nervous System Injury after Radiotherapy
Chinese Journal of Rehabilitation Theory and Practice 2007;13(9):862-863
Radiotherapy,as one of the combined treatments of malignancy tumor,plays an important role in some kinds or some special positions.But the rays can also damage the tissues around which resulted in some complications.The nerve tissue is vulnerable and the treatment results are limited.The damage manifestations of nervous system after radiotherapy were reviewed,and the knowledge of this problem was hoped to developed.
2.Evaluation of Different Screening Methods in Diagnosis of Cervical Cancer
Yuebo YANG ; Yu ZHANG ; Hong TANG
Chinese Journal of Primary Medicine and Pharmacy 2010;17(z2):27-29
Objective To retrospectivly analyze the value of Pap smear,liquid-based cells, colposcopy and colposcopic cervical biopsy in the diagnosis of cervical cancer. Methods 116 cases of cervical cancer were retrospectively analyzed, and the value of Pap smear,liquid-based cells ,colposcopy,and colposcopic cervical biopsy in the diagnosis of cervical cancer were investigated. Result 116 patients were pathologically diagnosed with cervical cancer before and after surgery. Pap smear was performed for 30 patients (25.9%) ,and 10 patients (33.3%) were detected with HSIL. Liquid-based cells was performed for47 patients (40.5%) ,and 25 patients (53.1%) were detected with HSIL. Colposcopy was performed for 99 patients (85.3%), and 75 patients (75.8 % ) were detected with HSIL or invasive cancer. Preoperative colposcopic biopsy was performed for 99 patients, and the pathological coincidence rate was 94.9%. There was no significant difference statistically between two cytology screening ( P > 0.05 ). There was significant difference statistically between liquid-based cells and colposcopy ( P < 0.01 ). There were significant differences statistically among liquid-based cells,colposcopy ,and colposcopic cervical biopsy ( P <0.01 ). Conclusion Cytology, colposcopy, colposcopic cervical biopsy could not be individually more complete and accurate detection of cervical cancer. Colposcopy,colposcopic biopsy than cytology had higher accurate rate of diagnosis of cervical cancer. A reasonable combination of multiple detection methods could improve the diagnostic accuracy of cervical cancer.
3.The implementation effect and its influencing factors of clinical medical talents cultivation scheme in Xinjiang Medical University
Jinhua TANG ; Yu CHEN ; Huixia ZHANG
Chinese Journal of Medical Education Research 2011;10(7):773-776
ObjectiveTo understand the implementation effect and its influencing factors of clinical medical undergraduates' talents cultivation scheme in Xinjiang Medical University. Methods 421 clinical medical students completed questionnaire. The main contents of the survey are general situation, the factors and the implementation effect of the cultivation scheme, and so on. Results①The talents cultivation scheme is reasonable and feasible. ②The main factors which affect talents cultivation scheme of our school are the teaching plan arrangement and practical course arrangement. ③Talents cultivation scheme in the implementation process achieved some success, but the cultivation of humanistic quality should be enhanced, etc. ConclusionRenewed the education conception, optimize the clinical teaching structure, integrated teaching contents, updated teaching methods and means, and strengthened students' humanistic quality are the key factors of the higher medical institutions to cultivate high quality and comprehensive talents.
4.Carbamazepine induced megaloblastic anemia:a case report
Jun ZHOU ; Fengyun TANG ; Yu ZHANG
Chinese Journal of Geriatrics 2016;35(6):677-
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5.Investigation on Water Source Pollution by Cryptosporidium parvum and Giardia lamblia in the Small Towns and Villages in Shenzhen,China
Shuyuan YU ; Fei TANG ; Zhicheng ZHANG
Journal of Environment and Health 1989;0(06):-
Objective To investigate the water source pollution by parasitic protozoa in small towns and villages in Shenzhen,China,in order to present the data to establish the national hygienic standard for controlling parasitic protozoa pollution.Methods The samples of water source were collected from 8 village level water plants in Shenzhen.Giardia lamblia and Cryptosporidium were detected,according to the EPA methods,by filtering,rinsing,magnetic isolation and staining.Results Giardia lamblia was found in water sources of 6 water plants and Cryptosporidium was found in one water plant.Conclusion At present,some water sources of village level water plants where the reservoirs were used as the water source in Shenzhen have been polluted by Giardia lamblia and Cryptosporidium,that indicates the potentiality of the water-born-diseases in that areas.
6.Effect of Retroviral Vector-Mediated IL6/IL2 Fused Gene Transduction on B16 Melanoma Cells Adhesive and Metastatic Potential
Xiaodan YU ; Peixian TANG ; Mingwei ZHANG
Chinese Journal of Cancer Biotherapy 1995;0(02):-
In order to examine the feasibility of cytokine fusion gene transfer into tumor cells, a retroviral vector (pLXSN) for human interleukin 6/interleukin 2 (IL6/IL2) fusion gene was constructed by using PCR and ligating the 2 genes with a synthesized flexible linker. The IL6/IL2 fused gene was introduced into B16 melanoma cell line mediated by retrovirus and the changes of adhesive and metastatic ability of fused gene-modified cells were detected. The B16-IL6/ IL2 cells showed efficient expression of both cytokines and decreased binding affinity with extracellular matrix (Laminin and Matrigel), accompanying with decreased experimental metastatic potentials. These data suggest that the mechanism involving the decreased metastases may relate with the changes of biological characteristics and immune stimulating activity of gene-modified cells.
7.Comparison of tensile properties of palmar or dorsal placement of stitches in repairing the tendons across the joints
Yu ZHANG ; Jinbo TANG ; Bin WANG
Chinese Journal of Orthopaedic Trauma 2002;0(01):-
Objective This study was designed to evaluate the biomechanical properties in tendons across the joints when Palmar or dorsal stitches were used. Methods Twenty porcine tendons were transected and then repaired in zone Ⅱand divided into two groups,using modified Kessler by placing the stitches in volar or dorsal part of tendons.The repaired tendons were placed on a joint model with flexion of 60?. An instron tensile testing machine was used to investigate 2 mm gap formation force and ultimate tensile strength. Results 2 mm gap formation force and ultimate tensile strength were both higher when dorsal placement of stitches was used. Conclusions Dorsal placement of stitches was recommended for repairing the tendons across the joints because it can offer greater tensile strength.
8.Effects of Naolisu Granules on the Rat Models with Cerebral Ischemia
Xingrong TANG ; Shuibing ZHANG ; Shangzhen YU
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(05):-
[Objective] To observe the effect of Naolisu Granules (NG) for experimental cerebral ischemia in rats. [Methods] Rat models with cerebral ischemia was set up by embolization of middle artery. To observe the effects of NG on cerebrovascular permeability, cerebral water content was examined and cerebral Evans blue (EB) content was detected with chromatometry. Meanwhile, the effect of HG on cerebral histological structure was observed with hematoxylin and eosin(HE) staining method. [Results] NG decreased cerebral capillary permeability and cerebral edema ( P
9.Comparison of tensile strength between 4 different epitendinous sutures
Yu ZHANG ; Jinbo TANG ; Renguo XIE ;
Chinese Journal of Orthopaedic Trauma 2002;0(03):-
Objective To evaluate the effects of 4 different epitendinous sutures on the tensile strength of the repaired tendons. Methods 40 plantar flexion deep tendons from pigs were divided into 4 groups randomly, with 10 in each group. After the core suture of Modifier Kessler was applied, 4 epitendinous sutures at different distances from suture sites to broken ends (4mm, 7mm, 10mm, 12mm) were used respectively in each group to repair the transected tendons. MTS Instron 4411 was used to test the repaired tendons. Tensile strengths at 2mm gap formation and at the peak were collected for statistical analyses by ANOVA. Results In this test, the tensile strength was found to increase with the distance from suture sites to broken ends. The tensile strength in the 4mm group was significantly lower than that in the others. There was little statistical difference between the other 3 groups. Conclusion Tensile strength of the repaired tendon tends to increase with the distance from suture sites to broken ends in epitendinous suture.
10.The value of serum procalcitonin in the treatment of acute exacerbation of asthma
Wei LONG ; Jianguo TANG ; Juan XIE ; Yu ZHANG ; Yicui ZHANG
Chinese Journal of Emergency Medicine 2010;19(9):927-930
Objective To evaluate the value of serum procalcitonin (PCT) in antibiotics used for the treatment of acute exacerbation of asthma. Method From February 2007 to July 2009, a total of 158 patients with asthma were randomly (random number) assigned to PCT group ( n = 77) or to control group ( n = 81 ). The PCT levels of all patients were measured. On the bases of routine treatment, the employment of antibiotics in control group was determined by the guidebook, and patients in the PCT group were treated with antibiotics guided by the levels of serum PCT. The antibiotics treatment was employed as PCT level >0.25 ng/mL, and was not employed as PCT level < 0.25 ng/mL. The rates of antibioties employment were observed. Results The rate of antibiotics employment in PCT group (45.4%) was lower than that of the control group (77.8%) (x2 = 17.15,P =0.000). Conclusions PCT could be used safely as guidance of antibiotics employment for the treatment of patients with acute exacerbation of asthma, leading to appropriate use of antibiotcs.