1.Clinical data analysis of severe acute paraquat poisoning.
Chinese Journal of Industrial Hygiene and Occupational Diseases 2010;28(10):786-787
Adolescent
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Adult
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Female
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Herbicides
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poisoning
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Humans
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Male
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Middle Aged
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Paraquat
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poisoning
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Rural Population
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Young Adult
2.Remote intelligent Brunnstrom assessment system for upper limb rehabilitation for post-stroke based on extreme learning machine.
Yue WANG ; Lei YU ; Jianming FU ; Qiang FANG
Journal of Biomedical Engineering 2014;31(2):251-256
In order to realize an individualized and specialized rehabilitation assessment of remoteness and intelligence, we set up a remote intelligent assessment system of upper limb movement function of post-stroke patients during rehabilitation. By using the remote rehabilitation training sensors and client data sampling software, we collected and uploaded the gesture data from a patient's forearm and upper arm during rehabilitation training to database of the server. Then a remote intelligent assessment system, which had been developed based on the extreme learning machine (ELM) algorithm and Brunnstrom stage assessment standard, was used to evaluate the gesture data. To evaluate the reliability of the proposed method, a group of 23 stroke patients, whose upper limb movement functions were in different recovery stages, and 4 healthy people, whose upper limb movement functions were normal, were recruited to finish the same training task. The results showed that, compared to that of the experienced rehabilitation expert who used the Brunnstrom stage standard table, the accuracy of the proposed remote Brunnstrom intelligent assessment system can reach a higher level, as 92.1%. The practical effects of surgery have proved that the proposed system could realize the intelligent assessment of upper limb movement function of post-stroke patients remotely, and it could also make the rehabilitation of the post-stroke patients at home or in a community care center possible.
Algorithms
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Arm
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physiopathology
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Artificial Intelligence
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Humans
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Movement
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Recovery of Function
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Reproducibility of Results
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Software
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Stroke Rehabilitation
3.Clinical efficacy of combined portal vein resection and construction in the treatment of hilar cholangiocarcinoma: A Meta-analysis
An YU ; Qiang HUANG ; Chenhai LIU ; Xiansheng LIN ; Fang XIE
Chinese Journal of Digestive Surgery 2017;16(1):65-70
Objective To systematically evaluate the safety and effectiveness of combined portal vein resection and reconstruction in the resection of hilar cholangiocarcinoma.Methods Literatures were researched using Cochrane Library,PubMed,Embase,China Biology Medicine disc,China National Knowledge Infrastructure,Wanfang database,VIP database from January 31,2006 to January 31,2016 with the key words including “hilar cholangiocarcinoma”“Klatskin tumor”“Bile duct neoplasm”“Vascular resection”“portal vein resection”“肝门部胆管癌”“血管切除”“门静脉切除”.The clinical studies of resection of hilar cholangiocarcinoma with portal vein resection and construction and without vascular resection and construction were received and enrolled.Two reviewers independently screened literatures,extracted data and assessed the risk of bias.Patients who underwent resection of hilar cholangiocarcinoma combined with portal vein resection and reconstruction were allocated into the portal vein resection group and patients who didn't undergo vascular resection were allocated into the no vascular resection group.Analysis indicators included (1) results of literature retrieval;(2) results of Meta-analysis:① incidence of postoperative complications (hepatic failure,biliary fistula,intra-abdominal hemorrhage),② postoperative mortality,③ patients' prognosis,④ related indicators of postoperative pathology (lymph node metastasis rate,moderate-and low-differentiated rate,nerve invasion rate,negative rate of resection margin).The heterogeneity of the studies was analyzed using the I2 test.The hazard ratio (HR) and 95% confidence interval (CI) were used for assessing the prognostic indicators.The incidence of complications,mortality and pathological indicators were evaluated by the odds ratio (OR) and 95% CI.Results (1) Results of literature retrieval:13 retrospective studies were eurolled in the meta-analysis,and the total sample size was 1 668 cases including 437 in the portal vein resection group and 1 231 in the no vascular resection group.(2) Results of Meta-analysis:① incidence of postoperative complications was respectively 39.86% in the portal vein resection group and 35.27% in the no vascular resection group,with no statistically significant difference between the 2 groups (OR =1.12,95% CI:0.82-1.53,P >0.05).The results of subgroup analysis showed that hepatic failure,biliary fistula and intra-abdominal hemorrhage were postoperative main complications,and the incidences were 17.09%,8.79%,6.25% in the portal vein resection group and 10.62%,9.69%,2.51% in the no vascular resection group,respectively,with no statistically significant difference between the 2 groups (OR =0.48,1.13,0.82,95% CI:0.23-1.02,0.45-2.83,0.21-3.12,P > 0.05).② Postoperative mortality was respectively 5.38% in the portal vein resection group and 3.88% in the no vascular resection group,with no statistically significant difference between the 2 groups (OR =1.16,95% CI:0.62-2.14,P > 0.05).③ There was statistically significant difference in patients' prognosis between the 2 groups (HR =1.81,95% CI:1.52-2.16,P < 0.05).④ The related indicators of postoperative pathology:lymph node metastasis rate,moderate-and low-differentiated rate and negative rate of resection margin were 41.55%,76.42%,63.74% in the portal vein resection group and 33.42%,66.75%,64.29% in the no vascular resection group,respectively,with no statistically significant difference between the 2 groups (OR =1.45,1.59,0.67,95% CI:0.95-2.21,0.97-2.61,0.37-1.20,P > 0.05).The nerve invasion rate was 83.47% in the portal vein resection group and 64.90% in the no vascular resection group,with a statistically significant difference between the 2 groups (OR =2.61,95 % CI:1.45-4.70,P < 0.05).Conclusion Combined portal vein resection and reconstruction is safe and feasible in the treatment of hilar cholangiocarcinoma,and the prognosis of patients with portal vein invasion is worse than that without portal vein invasion.
4.The Measurement of Hippocampal T_2 Relaxation Time in Healthy Chinese and Its Influencing Factors
Chun FANG ; Erzhen WANG ; Qiang BAO ; Fangrong YU ; Lizhang WANG
Journal of Practical Radiology 1991;0(03):-
0.05).However,HCT2s of right side and left side were significantly negatively correlated to age(r=-0.606,-0.522;P=0.000,0.000).Conclusion HCT2s in healthy Chinese aged 10~59 year measured on SE dual echo images are quite stable,and age is an influencing factor of HCT2,but not side,sex and handedness.
6.Microglandular adenosis of breast: report of a case.
Gui-mei QU ; Zhi-qiang LANG ; Wei-dong YAO ; Guo-hua YU ; Wen-fang YU
Chinese Journal of Pathology 2007;36(9):643-644
7.Applied research of intermaxillary fixation screw in the jaw fracture.
Wei HUANG ; Zhi-qiang CAO ; Dong FANG ; Zhen-yu HU
Chinese Journal of Plastic Surgery 2004;20(5):364-365
OBJECTIVETo evaluate and generalize the application of intermaxillary fixation screw in the jaw fracture.
METHODS41 cases of jaw fracture have been treated with intermaxillary fixation screw.
RESULTSBoth function and appearance have recuperated in 40 cases except 1 case has light malocclusion.
CONCLUSIONSApplication of intermaxillary fixation screw advanced the traditional therapy.
Adolescent ; Adult ; Bone Screws ; standards ; Female ; Humans ; Jaw Fractures ; surgery ; Male ; Maxillary Fractures ; surgery ; Middle Aged ; Orthopedic Fixation Devices ; standards ; Reconstructive Surgical Procedures ; instrumentation ; methods ; Treatment Outcome
8.Study on the perioperative changes of electrogastrogram of thoracic (tube) stomach in patients with esophageal cancer
Yang YUAN ; Boxiong CAO ; Yan XIA ; Qiang FANG ; Bo XIAO ; Yu QIU ; Guangguo REN
Chinese Journal of Digestive Surgery 2015;14(12):997-1001
Objective To investigate the perioperative characteristics and changing trends of gastric electrical activity of thoracic (tube) stomach in patients with esophageal cancer.Methods The clinical data of 30 patients with esophageal cancer who were admitted to the Sichuan Cancer Hospital between March 2013 and November 2013 were prospectively analyzed.All the eligible patients underwent esophageal cancer resection by Ivor-Lewis according to the inclusion criteria.The electrogastrograms of patients were recorded at preoperative day 1 and at postoperative day 3,7, 11 and 30.The electrogastrograms of patients at preoperative day 1 were used as the control.The parameters of electrogastrogram were analyzed including main frequency, coefficient of dominant frequency instablility, main power, postprandial/preprandial power ratio, percentage of normal gastric slow wave,percentage of slow gastric slow wave and percentage of tachycardia gastric slow wave.Measurement data with normal distritution were presented as x ± s, and measurement data with skew distritution were presented as M (Qn).The postoperative time and pre-and post-prandial electrogastrograms were compared by the repeated measures two-way ANOVA.The comparison between groups were evaluated with the LSD test and analysis of variance.Results Thirty patients were screened for eligibility with a mean age of 62 years (range, 49-75 years), including 26 males and 4 females.The pre-and post-prandial main frequencies were changed from 2.83 ± 0.13 and 3.01 ± 0.17 before operation to 2.66 ± 0.10 and 2.82 ± 0.10 at postoperative day 30 with coherent changing trend.The main frequencies at postoperative each time points were significantly lower than those before operation while postprandial above indicators were higher than preprandial those, showing a significant increasing trend with the passage of postoperative time (F =285.62, P < 0.05).There was no interaction between the time and meal (F =0.22, P > 0.05).The pre-and post-prandial coefficients of dominant frequency instablility were changed from 0.133 ±0.031 and 0.045 ±0.019 before operation to 0.150 ±0.043 and 0.115 ±0.010 at postoperative day 30 with coherent changing trend, and coefficients of dominant frequency instablility at postoperative each time points were significantly higher than those before operation while postprandial above indicators were lower than preprandial those, showing a significant reducing trend with the passage of postoperative time (F =16.51, P < 0.05).The pre-and post-prandial main powers were changed from (85 ± 15) μV and (149 ± 23) μV before operation to (74 ± 9) μμV and (98 ± 10) μV at postoperative day 30, and main powers at postoperative each time points were significantly lower than those before operation, showing a significant increasing trend with the passage of postoperative time (F =48.45, P < 0.05).There was interaction between the time and meal (F =7.39, P < 0.05).The postprandial/preprandial power ratio was changed from 3.00 ± 0.35 before operation to 2.52 ± 0.25 at postoperative day 30, and postprandial/preprandial power ratios at postoperative each time points were significantly lower than those before operation, showing a significant increasing trend with the passage of postoperative time (F =26.66, P < 0.05).The pre-and post-prandial percentages of normal gastric slow wave were changed from 81% ± 6% and 94% ± 5% before operation to 57% ± 5% and 70% ± 5% at postoperative day 30 with coherent changing trend, and percentages of normal gastric slow wave at postoperative each time points were significantly lower than those before operation while postprandial above indicators was lower than preprandial those, showing a significant increasing trend with the passage of postoperative time (F =49.36,P <0.05).There was no interaction between the time and meal (F =0.24, P > 0.05).The pre-and postprandial percentages of slow gastric slow wave were changed from 17% ± 7% and 4% ± 4% before operation to 32%±4% and 21%±4% at postoperative day 30 with coherent changing trend, and percentages of slow gastric slow wave at postoperative each time points were significantly higher than those before operation while preprandial above indicators were higher than postprandial those, showing a significant reducing trend with the passage of postoperative time (F =46.54, P < 0.05).There was interaction between the time and meal (F =18.12, P < 0.05).The pre-and post-prandial tachycardia gastric slow wave percentages were changed from 1.55% (1.04%,2.21%) and 1.95% (1.74%, 4.22%) before operation to 8.97% (5.76%, 12.02%) and 12.41% (8.04%,16.85%) at postoperative day 30 without completely coherent changing trend, and percentages of tachycardia gastric slow wave at postoperative each time points were significantly higher than those before operation while postprandial above indicators were higher than preprandial those, showing a significant difference between before operation and postoperative day 3 (Z =11.47, 13.28, P < 0.05) and no significant difference among the postoperative day 7, 11, 30 (Z =1.88, 0.31, 0.03, P > 0.05).There was no interaction between the time and meal (F=0.85, P<0.05).Conclusions After the esophagectomy, gastric electrical activity of thoracic (tube) stomach is also retained before and after the meal.There are significant differences among the main frequency, main power, coefficients of dominant frequency instablility, postprandial/preprandial power ratio,percentage of normal gastric slow wave, percentage of slow gastric slow wave, percentage of tachycardia gastric slow wave of thoracis (tube) stomach, they have changed dynamically in the perioperative period.
9.Extraskeletal myxoid chondrosarcoma:a clinicopathological analysis
Sangao FANG ; Yu LI ; Qiang MA ; Juan DU ; Li LIN ; Hualiang XIAO
China Oncology 2013;(9):728-732
Background and purpose: Extraskeletal myxoid chondrosarcoma (EMC) is a malignancy of uncertain differentiation tumor characterized by a multinodular structure and abundant myxoid matrix. Its preferred sites were the deep soft tissues of the extremities. The aim of this study was to investigate the clinicopathologic characteristics, diagnosis and differential diagnosis of EMC. Methods: Seven cases of EMC were analyzed for clinicopathological and immunohistochemical features with review of the related literature. Results: It occurred predominantly in females (male/female=2︰5). Five cases were located in low extremities and two in upper limb girdles, more commonly near the joint. Grossly, the masses showed as grey, lobular and somewhat transparent with a relatively well-deifned margin. Microscopically, the small ovary or plump spindle-shaped cells arranged in strand and cord patterns and lobular architecture which separated by delicate fibrous networks with an abundant myxoid but hypovascular background. And the tumors were immunoreactive for vimentin, and partly for S-100 and EMA, meanwhile, negative for CK. Conclusion:EMC is a rare soft tissue sarcoma with distinctive histopathological features. It should be distinguished from some mimics especially those tumors with a myxoid stroma or chondroid differentiation, such as chordoma and chondrosarcoma.
10.Assessment of ascending aortic elasticity in hypertension patients by quantitative tissue velocity imaging.
Yongping, LU ; Youbing, DENG ; Qiang, WANG ; Fang, CHEN ; Yanling, HUANG ; Yanfen, LV ; Huali, ZHANG ; Fei, YU
Journal of Huazhong University of Science and Technology (Medical Sciences) 2009;29(6):782-5
The elasticity of the ascending aorta in healthy volunteers and hypertension patients were examined by using quantitative tissue velocity imaging (QTVI), and the age-related change in the ascending aortic elasticity was investigated. The anterior and posterior walls of the ascending aorta were imaged with tissue Doppler method in all the subjects and QTVI was performed. Stable curves were obtained from 173 hypertension patients and 185 healthy adults. The peak early diastolic velocity (V(e)), peak late diastolic velocity (V(a)) and peak systolic velocity (V(s)) were measured. The relation of age with these measures was assessed. The results showed that the elasticity of the ascending aorta was much lower in the hypertension patients than in normal controls (P<0.05), and the elasticity was decreased with age in both groups (P<0.05). Our results suggested that QTVI, a new non-invasive ultrasonic technique, is helpful for the assessment of the aortic elasticity in hypertension patients.