Objective In this report the proteomics technique was used for analysis of the Molecu-lar marker related acute rejection after liver transplantation.Methods Highly abundant proteins in human serum were deleted using Aurum Serum Protein Mini Kit and separated by 2-DE.The maps were analyzed by ImageMaster 2D Platinum software.The differential proteins on the gel were did in gel digestion with trypsin and then identified by nanoUPLC-ESI-MS/MS.Results Reproducible 2-DE image was successfully ob-tained.2 up-regulated expressed protein spots were identified clearly are serum amyloid A protein.Conclu-sions In this study, it was confirmed that SAA expression upregulate after transplantation in patients with acute rejection by proteomics technique, This method may provide clues to the early diagnosis of liver al-lograft rejection.

Children are special groups who grow rapidly,the characteristics of physical growth are discontinuous,and individual in different stages.Growth level,growth velocity and proportion of body need in consideration for a proper assessment and explanation of growth status in children.

The medical ethics professionals which have resourceful ethical knowledge ought to give full play to subjects superiority in the review of the clinical trials involving human subjects. Before ethical review, it is needed to learn the series of international and domestic laws, regulations, and documents, and communicate with peers timely. In the review, they should focus on the necessity and security of the research project, conduct a compre-hensive review combined with the principle of medical ethics, and master the review key point of informed consent, to fulfill their duty of protection of human rights of subjects.

Objective To investigate the clinical effects of VATS lobectomy and VATS segmentectomy in the treatment of old age patients with non small cell lung cancer for stage Ⅰ.Methods 140 patients with non small cell lung cancer for stage Ⅰ were chosen and randomly divided into two group including group A(70 patients)with VATS lobectomy and group B(70 patients)with VATS segmentectomy;and the perioperative clinical indicators,level of lung function and CRP before and after operation and survival rate with follow-up of both groups were compared.Results The operation time,intraoperative blood loss amount,chest drainage volume and time and hospitalization staying time of group B[(118.15±33.61)min,(59.25±10.61)ml,(641.56±135.17)ml,(3.42±0.77)d and(5.08±1.32)d] were significantly better than group A[(135.33±40.10)min,(83.33±14.15)ml,(783.89±180.61)ml、(4.38±0.94)d和(6.52±1.58)d](P<0.05).There was no significant difference in the number of lymph node dissection between group A(12.67±2.64)and group B(12.38±2.58)(P<0.05).The levels of FVC and FEV1 after operation of group B was significantly higher than group A(P<0.05).The levels of CRP after operation of group B was significantly lower than group A(P<0.05).There was no significant difference in the 1 year survival rate with follow-up between group A(94.29%)and group B(94.29%)(P>0.05).Conclusion Compared with VATS lobectomy,VATS segmentectomy in the treatment of old age patients with non small cell lung cancer for stage Ⅰ can efficiently reduce surgical trauma degree,accelerate the recovery process of body,protect the lung ventilation function and be helpful to reduce the inflammatory response levels.

OBJECTIVE: To provide reference for the application of automatic tablet packing machine in the inpatients dispensary.METHODS: The working principle and flow,the main structure and function of the automatic tablet packing machine used in our hospital were introduced,and its application value was evaluated and the problems remained to be dealt with were pointed out.RESULTS: The automatic tablet packing machine had the advantages of high accuracy and efficiency,and reduced working intensity,however,the costs for the packaging and consumables,and the low drug quality were the problems remained to be solved.CONCLUSIONS: Automatic tablet packing machine is suitable for the dispensing of oral single dose of tablets for inpatient patients,and it helps to improve the work quality and the service level in the dispensary for inpatients.

0.05).There was significant difference in time of treatment and severeness score after three days and seven days(P

Objective To observe the effect on depressurization and quality of life through Jiangya capsule combined with nimodipine treatment.Methods Randomized,blind and control trial was applied.One hundred and twenty elderly isolated systolic hypertension (EISH) patients were randomly assigned to Jiangya capsule combined with nimodipine group (treatment group) 60 cases (6 cases were lost and 54 cases were in analysis) or nimodipine group (control group) 60 cases (13 cases were lost and 47 cases were in analysis).Treatment group was administrated with Jiangya capsule and nimodipine,and control group was administrated with nimodipine and Jiangya capsule placebo.The course of treatment was 4 weeks.The blood pressure and quality of life of the two groups were observed before and after treatment.Results SBP was obviously decreased in treatment group compared with control group (P0.05).Symptom scores of yin deficiency and yang hyperactivity syndrome in treatment group was improved and superior to the other syndromes in treatment group and control group (P

Child ; Humans ; Male ; Thyroiditis, Suppurative ; pathology

The antifungal susceptibility testing is playing important roles which include: understanding the susceptibility of the fungus to the antifungal agents and monitoring the resistance during therapy.Our purpose in this editorial is to tell the readers the proper application of MIC detection;to emphasize the clinical relevance of the in vitro susceptibility,and especially,to introduce the recent clinical study data which give the detailed explanation on the clinical relevance of MIC.

The introduction of lipid-formula Amphotericin B,Voriconazole,and Echinocandins,including Caspofungin and Micafungin,reflect the trend that the antifungal drugs are being developed along to a direction with high effect,broad spectrum,and low toxicity.These drugs undoubtedly provide novel useful approaches to the treatment of invasive fungal infections.Compared to the traditional antifungal drug,such as amphotericin B and Fluconazole,these drugs have the character of good effect and low adverse effect,which will be very important to prophylaxis and treatment for systemic fungal infections.The information concerning for these issues is being reviewed in this paper.