1.Progresses in studies on neonatal septicemia.
Chinese Journal of Pediatrics 2010;48(1):32-35
Humans
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Infant, Newborn
;
Sepsis
;
diagnosis
2.The correlation between serum osteocalcin and parathyroid hormone levels in cancer patients and bone metastasis.
Cheng-yu JIN ; Yu-lin LI ; Tong ZHANG
Chinese Journal of Oncology 2008;30(8):614-615
Adult
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Aged
;
Aged, 80 and over
;
Bone Neoplasms
;
blood
;
secondary
;
Female
;
Humans
;
Male
;
Middle Aged
;
Neoplasms
;
blood
;
pathology
;
Osteocalcin
;
blood
;
Parathyroid Hormone
;
blood
3.Analysis of paraquat intoxication epidemic (2002-2011) within China.
Yu YIN ; Xiang GUO ; Shou Lin ZHANG ; Cheng Ye SUN
Biomedical and Environmental Sciences 2013;26(6):509-512
Adolescent
;
Adult
;
Child
;
Child, Preschool
;
China
;
epidemiology
;
Disease Outbreaks
;
Female
;
Herbicides
;
poisoning
;
toxicity
;
Humans
;
Infant
;
Infant, Newborn
;
Male
;
Middle Aged
;
Paraquat
;
poisoning
;
toxicity
;
Risk Factors
;
Time Factors
;
Young Adult
4.A study of the relationship between pathological anatomy of pancreaticobiliary maljunction and pancreatic and biliary diseases
Lin CHENG ; Ziqin ZHANG ; Chenglin WANG ; Yongqiang YU
Chinese Journal of Hepatobiliary Surgery 2011;17(10):801-804
The widespread availability of multi-detector spiral CT and its post processing techniques,and MRI,provide us with important tools to carry out anatomical studies on pancreaticobiliary maljunction (PBM).Determining the relationship between PBM and biliary diseases contributes not only to a better understanding of pathogenesis and pathological process of biliary diseases,but it also provides evidence for prophylactic treatment.The present study reviewed the definition,classification,pathological anatomy of PBM,relationship between PBM and pancreaticobiliary diseases,and clinical treatments of PBM.
6.Imaging diagnosis of osteopoiknosis: a report of 6 cases in four generations of one family and 3 sporadic cases.
Wu-jiang YU ; Ting-song FANG ; Lin-gang CHENG
China Journal of Orthopaedics and Traumatology 2016;29(6):566-569
OBJECTIVETo analyze the imaging features of osteopoikilosis and its diagnosis knowledge.
METHODSThe imaging data of 9 patients with osteopoikilosis were analyzed retrospectively, including 6 familial cases and 3 sporadic cases. In 6 familial cases,there were 4 males and 2 females with an average age of 28 years old ranging from 10 to 63 years. Clinical manifestations of 1 familial case were left knee pain and limitation of activity for 3 years, and other 5 cases without clinical manifestation. In 3 sporadic cases, there were 2 males and 1 female with an average age of 33.7 years old ranging from 25 to 44 years. Three sporadic cases had obvious injury history with following up from 6 to 12 months. All imaging results of 9 cases were observed.
RESULTSThe imaging data of 6 familial osteopoikilosis showed the multiple round or oval nodes within bone with clear margins, uniform density, different size. The occurrence of the hyperostotic spots preferentially localized in the epiphyses and metaphyses of the long bones, and carpus and tarus. X-ray features of 3 sporadic osteopoikilosis were similar to that of 6 familial cases and for 6 to 12 months follow-up X-ray features were unchanged.
CONCLUSIONThe imaging features of osteopoikilosis are relatively specific such as the multiple mottling dense focal within bone with clear border and bilateral symmetry, and the focus located on cancellous bone and the diaphyses usually is unaffected. The imaging is a valuable examination for the accurate diagnosis of osteopoikilosis.
Adolescent ; Adult ; Child ; Female ; Humans ; Male ; Middle Aged ; Osteopoikilosis ; diagnosis ; diagnostic imaging ; Pedigree ; Radiography ; Young Adult
8.Significance of transcatheter arterial chemoembolization combined with sorafenib for the treatment of primary hepatocellular carcinoma
Lin ZHENG ; Chenyang GUO ; Hailiang LI ; Hongtao CHENG ; Pu YU
Chinese Journal of Digestive Surgery 2013;(3):236-237
Transcatheter arterial chemoembolization (TACE) was the preferred method of non-operation treatment for hepatocellular carcinoma (HCC).Radical resection of HCC remains difficult,extrahepatic metastasis was not easy to deal with,and repeated treatment aggravated the liver injury,so the long-term efficacy was poor.Sorafenib could control tumor angiogenesis and block the proliferation of tumor cells.A male patient with primary HCC and in the stage Ⅱb according to the Chinese clinical liver cancer staging system was treated by TACE combined with sorafenib and antiviral treatment in Henan Cancer Hospital.After the treatment,the intrahepatic lesions were inactive,and the pulmonary metastasis was partially relieved.The patient was followed up till May 2012,and the survival time was 39 months.The hepatic function was normal,and the hepatitis B virus (HBV) replication was negative.No intervention treatmentrelated complications were detected,and the KPS score was 100.
9.The Effects of Suanzaoren decoction on hippocampus, cortex BDNF and TrKB geneexpression in depression rats
Xusheng TIAN ; Haiyang YU ; Yan YAN ; Lin SONG ; Wei CHENG
International Journal of Traditional Chinese Medicine 2014;(7):633-636
Objective To investigate the effect of Suanzaoren Decoction on hippocampus, cortex BDNF and TrKB gene expression in depression model rats. Methods Depression rat models were established by social-isolated raise and chronic stress stimulation. Suanzaoren decoction was administrated to the models. RT-PCR was adopted to detect the expression of mRNA BDNF and TrKB genes. Results The mRNA expression of BDNF and TrKB in cortex of Suanzaoren decoction high dose group、medium dose group and clomipramine group(0.213±0.094, 0.639±0.023, 1.032±0.015, 1.089±0.014, 1.580±0.012, 1.860±0.019)were all higher than the model group(0.032±0.008, 0.001±0.000), showing a significant difference among four groups (P<0.01), and the mRNA expression of BDNF and TrKB in hippocampus of Suanzaoren decoction high dose group, medium dose group and clomipramine group(0.213±0.094, 0.639±0.023, 1.032±0.015, 1.089±0.014, 1.580± 0.012, 1.860±0.019)were higher than the model group (0.021±0.015, 0.125±0.013), there was a significant difference between four groups(P<0.01). Compared with the model group, the mRNA expression of low-dose group of Suanzaoren decoction in both cortex and hippocampus of BDNF and TrKB was not significantly different to the model group(P>0.05). Conclusion Suanzaoren decoction can increase the expression of BDNF and TrKB gene, promote neuronal proliferation, and resist depression.
10.Integrated CAMVA and BCOP methods to predict eye irritation caused by cosmetics
Yao QIN ; Shujun CHENG ; Jiancong HUANG ; Lin HUANG ; Yu CHEN
Chinese Journal of Comparative Medicine 2014;(6):78-82
Objective To explore the use of integrated two methods in vitro in prediction of eye irritation caused by cosmetics.Method Chorioallantoic membrane vascular assay ( CAMVA), bovine corneal opacity and permeability (BCOP) and Draize rabbit eye irritation test were used to determine the predictive potential of eye irritation of 60 kinds of cosmetics.Results CAMVA method was able to distinguish 41 non-irritant samples and 18 irritant samples.BCOP method was able to predict 35 non-irritant samples , 21 mild-moderate irritant samples and 4 severe irritant samples . Combination of CAMVA and BCOP methods could obviously improve the identification ability of irritation , and the classification consistency with Draize rabbit eye irritation testing reached 98.3%.Conclusions The integrated test strategy combined BCOP with CAMVA can be used to appropriately predict ocular irritation of cosmetics , with a prediction range covering non-irritant to severe irritant samples .