No abstract available.
Alcoholics* ; Humans

This study was performed to investigate the stimulating effect on oocyte maturation and cumulus cell expansion in TC199 media by human cord serum (HCS) supplementation. Immature mouse oocyte cumulus complexes (OCCs) were cultured in TC199 media supplemented with bovine serum albumin (BSA), HCS and human chorionic gonadotropin (hCG) instead of luteinizing hormone (LH) respectively, and the expression of cumulus expansion and oocyte maturation were observed. After 4hr and 24hr culture with or without OCCs, media containing 0.4% BSA, 10% HCS and 10 lU hCG respectively were collected and analyzed for changing concentrations of estradiol (E2), progesterone(P4), testosterone(T), and PGF2. There were no elevation of E2, T, and PGF2 by OCCs culture, but minute elevation of P4 level by 24hr OCCs culture in hCG supplementation (p=0.048). The stimulating pattern of cumulus expansion of OCCs by HCS and hCG supplementation was similar to our previously report using Ham's F-10 media, however oocyte maturation rates after 24hr OCCs culture in all media were increased by 20~30% compared to Ham's F-10 media. These results suggest that LH in HCS induce cumulus expansion probably by P4 secretion of OCCs, and TC199 is efficient media for immature mouse oocyte maturation.
Animals ; Chorionic Gonadotropin ; Cumulus Cells* ; Dinoprost ; Estradiol ; Humans* ; Luteinizing Hormone ; Mice ; Oocytes* ; Serum Albumin, Bovine

The authors performed a retrospective review on 27 eyes of 23 children with vitreous hemorrhage, to assess the natural history, the outcome of vitrectomy and the important prognostic factors. Mean age was 3. 7 years(range: birth~13.5 years). The causes of vitreous hemorrhage included trauma(6 patients), retinopathy of prematurity(5 patients), persistent hyperplastic primary vitreous(4 patients)and others(8 patients). Spontaneous absorption of vitreous hemorrhage in 11 of 27 eyes was observed and took mean 2. 5 months. Sixteen eyes had undergone vitrectomy for persistent vitreous hemorrhage(mean duration: 3. 4 months). Follow up period was mean 32. 8 months(range: 20~79 months). Visual improvement was achieved in 70%of all patients and there was no statistical significance between spontaneous absorption group and vitrectomy group. Deprivation amblyopia was complicated in 7 of 9 patients whose visual acuity could be measured in both eyes. anisometropic myopia(> OR =2. 0 diopter)was observed in 7 of 14 patients. Our results supported that causes of vitreous hemorrhage in children was variable and early vitrectomy and postoperative correction with occlusion therapy might be essential in treatment of childhood vitreous hemorrhage.
Absorption ; Amblyopia ; Child* ; Follow-Up Studies ; Humans ; Natural History ; Prognosis* ; Retrospective Studies ; Visual Acuity ; Vitrectomy ; Vitreous Hemorrhage*

Sixteen eyes of 8 premature infants with stage 3 retinopathy of prematurity were treated with cryotherapy. Transconjunctival or transscleral cryotherapy was applied to the avascular retina with a cataract cryoprobe under general anesthesia. The mean follow up period was 8.2 months with a range of 4.5 to 14 months. Twelve(75%) of 16 treated eyes showed complete resolution of retinopathy of prematurity, while 4(25%) of 16 treated eyes showed cicticial change: 1 eye became cicatricial Grade I and 3 eyes Grade II.
Anesthesia, General ; Cataract ; Cryotherapy* ; Follow-Up Studies ; Humans ; Infant, Newborn ; Infant, Premature ; Retina ; Retinopathy of Prematurity*

Sixteen eyes of 8 premature infants with stage 3 retinopathy of prematurity were treated with cryotherapy. Transconjunctival or transscleral cryotherapy was applied to the avascular retina with a cataract cryoprobe under general anesthesia. The mean follow up period was 8.2 months with a range of 4.5 to 14 months. Twelve(75%) of 16 treated eyes showed complete resolution of retinopathy of prematurity, while 4(25%) of 16 treated eyes showed cicticial change: 1 eye became cicatricial Grade I and 3 eyes Grade II.
Anesthesia, General ; Cataract ; Cryotherapy* ; Follow-Up Studies ; Humans ; Infant, Newborn ; Infant, Premature ; Retina ; Retinopathy of Prematurity*

LYODURA(R) is commercial name of a cleaned, desantigenized, desenzymatised, rendered free of pyogenics, sterilized by gamma rays, and lyophilized dura. Frontalis suspension with LYODURA(R) was performed to a total of 16 patients(21 lids) of congenital ptosis with levator muscle function of 3mm or less in the ptbtic lid. The follow-up period ranged from 2 to 39 weeks with a mean of 19.6 weeks. Postoperative lid levels were judged good, fair, and poor. Good results occurred in 12 of 21 procedures(57.1 %) and fair results in 6 of 21 prqcedures(28.6%). The summation of these two indicates an overall satisfactory result of 18 of 21 cases(85.7%).
Follow-Up Studies ; Gamma Rays

LYODURA(R) is commercial name of a cleaned, desantigenized, desenzymatised, rendered free of pyogenics, sterilized by gamma rays, and lyophilized dura. Frontalis suspension with LYODURA(R) was performed to a total of 16 patients(21 lids) of congenital ptosis with levator muscle function of 3mm or less in the ptbtic lid. The follow-up period ranged from 2 to 39 weeks with a mean of 19.6 weeks. Postoperative lid levels were judged good, fair, and poor. Good results occurred in 12 of 21 procedures(57.1 %) and fair results in 6 of 21 prqcedures(28.6%). The summation of these two indicates an overall satisfactory result of 18 of 21 cases(85.7%).
Follow-Up Studies ; Gamma Rays

Lyodura(R) is a commercial name of a cleaned, desantigenized, desenzymatized, rendered free of pyogenics, sterilized by gamma rays, and lyophilized dura. Frontalis suspension with Lyodura(R) was performed on a total of 16 patients (21 lids) of congenital ptosis with levator muscle function of 3mm or less in the ptotic lid. The follow-up period ranged from 2 to 39 weeks with a mean of 19.6 weeks. Postperative lid levels were judged good, fair, and poor. Good results occurred in 12 of 21 procedures (57.1%) and fair results in 6 of 21 procedures (28.6%). The summation of these two indicates an over all satisfactory result of 18 of 21 cases (85.7%).
Blepharoptosis/*congenital/therapy ; Child ; Child, Preschool ; Collagen/*therapeutic use ; Eyelids/surgery ; Humans ; Infant

The authors reviewed 3145 pediatric patients who visited the emergecy room in this hospital during 3yrs period from Jan. 1989 to Dec. 1991. 1) Among the patients visiting the emergency room, the patients under 15 years of age were 26.4% (3145) of total emergency patients (11930). 2) yearly distribution of patients were decreased 17% between 1989 and 1991. 3) Monthly distribution of visits showed higher incidence in June and July. The male to female ratio was 1.5:1. 4) Weekly distribution of visits showed higher incidence on Sunday and Saturday, relatively. 5) Most popular time of visiting the emergency room was between 8:00 PM to 12:00 PM during which time 29.5% of all pediatric patient were seen. 6) Distribution of age showed peak incidence between 6 and 12 years of age (30.9%). 7) 65.18% of total emergency room isits were pediatric patients. 8) Distribution of cases was as follows: Respiratory disease 37%, accident, GI disease in turn listed respectively in ecreasing order of freqency. 9) The admission rate through emergency was 8.5% of total pediatric emergency patients. 10) 82.3% of total emergency visits had medical insurance coverage, 7% had no insurance and 10.7% were on medical aid program.
Emergencies* ; Emergency Service, Hospital* ; Female ; Humans ; Incidence ; Insurance ; Insurance Coverage ; Male

The retinal vascular changes and the results of treatment were studied in five incontinentia pigmenti patients. All patients were female and had a mean follow-up of 4 1/2 years (7 months~7 1/2 years). Abnormal retinal vascular changes included peripheral avascular retina, retinal and preretinal neovascularization, and dilated, tortuous retinal vessels. Two of them were treated; one received a cryotherapy and the other a laser photocoagulation to the avascular retinal area and showed regression of abnormal vessels. At last follow-up, no eye developed retinal detachment, but traction of the peripheral retina by a vitreous band was visible in three patients. One showed a degenerative macula and an atrophy of the retinal pigment epithelium in the papillomacular bundle area. Our result suggests that incontinentia pigmenti eyes may show retinal vascular changes very similar to that in retinopathy of prematurity, and can be effectively treated by destroying an avascualr retina if indicated.
Atrophy ; Cryotherapy ; Female ; Follow-Up Studies ; Humans ; Incontinentia Pigmenti* ; Light Coagulation ; Retina ; Retinal Detachment ; Retinal Pigment Epithelium ; Retinal Vessels ; Retinaldehyde* ; Retinopathy of Prematurity ; Traction