No abstract available.
Chin* ; Polyps* ; Skin*

No abstract available.
Nevus, Epithelioid and Spindle Cell*

No abstract available.
Castration ; Granuloma ; Granuloma, Foreign-Body

BACKGROUND: Chronic urticaria is defined as repeated episodes of wheals lasting for 6 weeks or longer. Nowadays, the role of vitamin D in various chronic diseases is a matter of great interest, but limited data is available on the vitamin D status in patients with chronic urticaria. OBJECTIVE: The goal of this study was to investigate the relationship between vitamin D status and clinical characteristics of chronic urticaria. METHODS: The clinical records of 72 patients with chronic urticaria, 26 with acute urticaria and 26 with atopic dermatitis, along with 72 healthy controls, were retrospectively reviewed. RESULTS: The serum 25-(OH)D3 level was found to be significantly reduced in patients with chronic urticaria compared to those in the other groups. In particular, the proportion of patients with critically low vitamin D levels (<10 ng/ml) was significantly higher in the chronic urticaria group than in the other groups. The serum vitamin D levels showed significant negative associations with urticaria activity score and disease duration. In addition, serum vitamin D levels were significantly lower in subjects with a positive autologous serum skin test than in subjects with a negative result. CONCLUSION: In conclusion, the serum vitamin D level was more likely to be critically low in patients with chronic urticaria, and an inverse relationship with disease severity and disease duration was observed. These findings may open up the possibility of the clinical use of vitamin D as a contributing factor in the pathogenesis of chronic urticaria and a predictive marker for disease activity in chronic urticaria.
Chronic Disease ; Dermatitis, Atopic ; Humans ; Retrospective Studies ; Skin Tests ; Urticaria* ; Vitamin D* ; Vitamins*

Morphea, localized scleroderma, is a connective tissue disease characterized by localized, circumscribed sclerotic patches, or plaques of the skin. The pathogenesis of morphea is still unclear. Central diabetes insipidus is a disease characterized by excessive thirst and urination. In more than half of the cases of central diabetes insipidus, the etiology is still unknown. We experienced the case of morphea and verruca plana in a 32-year old female with a history of central diabetes insipidus. Central diabetes insipidus might have influenced disrupting the homeostasis of the endocrine or immune environment. In the state of disrupted homeostasis, there might be an increased chance for morphea and disseminated verruca plana to develop easily. Based on this, we suppose the possible mechanism about the morphea and disseminated verruca plana developed in central diabetes insipidus.
Connective Tissue Diseases ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Female ; Homeostasis ; Humans ; Scleroderma, Localized ; Skin ; Thirst ; Urination ; Warts

Morphea, localized scleroderma, is a connective tissue disease characterized by localized, circumscribed sclerotic patches, or plaques of the skin. The pathogenesis of morphea is still unclear. Central diabetes insipidus is a disease characterized by excessive thirst and urination. In more than half of the cases of central diabetes insipidus, the etiology is still unknown. We experienced the case of morphea and verruca plana in a 32-year old female with a history of central diabetes insipidus. Central diabetes insipidus might have influenced disrupting the homeostasis of the endocrine or immune environment. In the state of disrupted homeostasis, there might be an increased chance for morphea and disseminated verruca plana to develop easily. Based on this, we suppose the possible mechanism about the morphea and disseminated verruca plana developed in central diabetes insipidus.
Connective Tissue Diseases ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Female ; Homeostasis ; Humans ; Scleroderma, Localized ; Skin ; Thirst ; Urination ; Warts

No abstract available.
Ficusin ; Follow-Up Studies ; Isotretinoin ; Methotrexate ; Mycosis Fungoides

No abstract available.
Erythema Nodosum* ; Erythema* ; Valproic Acid*