1.How much do community residents know about dermatosis and venereal diseases and its impact factors?
Qing XIANG ; Yu ZHU ; Yanming LIU
Chinese Journal of General Practitioners 2008;7(6):409-410
Randomized sampling-based questionnaire among 2000 community residents and personal contact with selected populations were conducted.Based on incidence or clinical featuxes of dermatosis and venereal diseases and recognition-related impact factor analyses,we provided evidence for community-based health education and behavior intervention.Our findings showed that itching was the most common skin disease,and fungous infection displayed an increasing trend.Viral diseases increased significantly in recent years.Patients failed to understand the skin diseases,although they partly had some misleading information about venereal diseases.Health care providers should perform more health education and behavior interventions regarding dermatosis and venereal diseases for community residents to improve their health condition or quality of life.
3.The value of isotropic scanning and lung care software of 16-slice spiral CT in the diagnosis of solitary pulmonary nodules
Rui XU ; Jian-Long LI ; Cheng XIANG ; Yu-Qing SHAN ;
Cancer Research and Clinic 2006;0(12):-
Objective To evaluate the diagnostic evaluation of isotropic scanning and Lung Care soft- ware in solitary pulmonary nodules,and to improve the diagnostic accuracy.Methods 52 patients suffered from SPN were included in our study.Two experts in CT analyzed the films.First,they read the axial images and made diagnosis.Then isotropic scanning and lung care software approaches were used on 16 spiral CT and another analysis were made again.The results were compared with pathological diagnosis respectively. Results Spiculated sign,lobulated sign,vessel convergence were found more on isotropic scanning approach, that had significant difference with axial images analysis(P
5.Matrix Metalloproteinase and Cerebrovsacular Diseases
Zhao-Bo ZHANG ; Qing-Hua LI ; Yu-Xiang WANG ;
International Journal of Cerebrovascular Diseases 2006;0(12):-
The recent studies have suggested that matrix metalloproteinases(MMPs)are close associated with the instability of atherosclerotic plaques,the formation and development of intracranial aneurysm,ischemic stroke and hemorrhagic transformation.The study and application of MMP inhibitor may become a new approach in the treatment of cerebrovascular diseases.
6.Color Doppler evaluation of tuberculous pelvic inflammation ovarian function
Qing-Yu XIANG ; Ling ZHANG ; Qing-Hua XIANG
Chinese Medical Equipment Journal 2017;38(12):73-76,83
Objective To observe the changes in ovary blood supply of the tuberculous pelvic inflammation patient before and after treatment by color Doppler to explore the influences of tuberculous pelvic inflammation on uterus and ovary functions from hemodynamic aspect as well as the rehabilitation of uterus and ovary functions after treatment.Methods The 17 tuberculous pelvic inflammation patients in the observation group and 17 healthy women at child-bearing period underwent color Doppler examination,and such indexes were measured as the peak systolic flow velocities of uterine artery and arteria ovarica (Vmax),resistance index (RI) and pulsatility index (PI).The measure values at all the stages were compared in the observation group,and then contrasted with those in the control group.The rehabilitation of ovary function was evaluated according to the measure values.Results The observation group had the Vmaxs of rami ovarii arteriae uterinae and arteria ovarica 3 months after treatment higher than those before treatment,and the Vmaxs of rami ovarii arteriae uterinae and arteria ovarica 1 a were significantly higher than those 6 months after treatment.The Vmaxs of rami ovarii arteriae uterinae and arteria ovarica in the observation group 3 months,6 months,1 a and 1.5 a after treatment were all higher statistically than those in the control group at corresponding periods.The observation group had the measure values of PI and RI before treatment as well as 3 months and 6 months after treatment obviously higher than those in the control group.The measure values of PI and RI 1 and 1.5 a after treatment in the observation group were also higher than those in the control group.Conclusion Uterine artery and arteria ovarica may have hemodynamic changes before and after pelvic tuberculosis treatment.Measuring the blood flow parameters of uterine artery and arteria ovarica before and after pelvic tuberculosis treatment contributes to evaluating pelvic tuberculosis treatment efficacy and predicting ovarian function rehabilitation after treatment.
7.Melancholia incidence in the convalescence period of cerebral hemorrhage and its correlated factors
Xiang-yu LIN ; Yu-hui LI ; Jing LI ; Jin-gang ZHANG ; Run-qing CHEN ;
Chinese Journal of Postgraduates of Medicine 2011;34(31):31-34
Objective To evaluate the melancholia incidence in the convalescence period of cerebral hemorrhage and its correlated factors.Methods Ninety-eight cerebral hemorrhage patients in the convalescence period were involved in this study.Melancholia was assessed by Hamilton depression scale (HAMD),neural functional deficiency was assessed by the national institute of health stroke scale (NIHSS),cognitive function deficiency was assessed by the Montreal cognitive assessment (MoCA) and neural functional deficiency recovery was assessed by modified Rankin scale (mRS).Hemorrhagic site and blood quantity were detected with CT.The blood flow of middle cerebral artery (MCA),anterior cerebral artery (ACA),posterior cerebral artery (PCA) was detected by TCD.Results The melancholia incidence in the convalescence period was 51.0%(50/98),34.0%(17/50) in males and 68.8%(33/48) in females,there was significant difference between the two (P < 0.05 ).The scores of NIHSS and mRS had significantly positive correlation with HAMD (P < 0.05 ),and had significantly negative correlation with MoCA (P < 0.05 ).When the hemorrhagic site was in frontal lobe and blood quantity was 20-40 ml,the melancholia incidence was increased [76.2% (16/21),62.5% (25/40)].The average blood velocity of MCA,ACA and PCA in melancholia patients was significantly slower than that without melancholia patients,while resistance index was significantly higher in melancholia patients (P < 0.05).Conclusions Melancholia incidence in the convalescence period of cerebral hemorrhage has positive correlation with sex,NIHSS,MoCA,hemorrhagic site and blood quantity.The average cerebral blood flow in the melancholia patients is significantly slower and resistance index is significantly higher.
8.Clinical features and correlation between radiographic parameters and incidence of calcaneal spur
Qing ZHANG ; Nan JIANG ; Weiran HU ; Zewei YU ; Xiang ZHANG ; Bin YU
Chinese Journal of Orthopaedic Trauma 2016;18(6):487-492
Objective To analyze the clinical features and the correlation between radiographic parameters and incidence of calcaneal spur in the patients from Nanfang Hospital,Southern Medical University,China.Methods Three experienced observers independently used the image acquisition and transmission system (PACS) to collect the data of lateral and axial X-ray images of calcaneus or ankle joint in neutral position from the patients with calcaneal spur and normal controls who had undergone radiological examination in Nanfang Hospital,Southern Medical University from July 2014 through December 2015.Ten radiological parameters of the foot (B(o)hler angle,Gissane angle,calcaneal inclination angle,talocalcaneal angle,talus horizontal angle,posterior facet inclination angle,calcaneal length,height of the posterior facet,absolute foot height,and calcaneal width) were measured in both the patients and normal controls.The location,morphology and length of calcaneal spurs were compared between genders,sides and age groups.Results A total of 216 parpatients were included in the study.Female patients were more than male ones,simple plantar spurs more than simple achilles tendon ones,type B spurs more than type A ones,the length of achilles tendon spurs larger than that of plantar ones,female plantar spurs more than males ones,and the length of right foot plantar spurs larger than that of left foot ones.All the differences above were statistically significant (P < 0.05).There were no significant differences in the location,morphology or length of calcaneal spurs between the age group of ≤ 60 years old and the age group of > 60 years old (P > 0.05).The incidence of calcaneal spur were significantly correlated to Gissane angle (P =0.000,OR =0.944,95% CI 0.917-0.973),posterior facet inclination angle (P=0.017,OR=0.957,95% CI 0.924-0.992) and height of the posterior facet (P =0.007,OR =0.933,95% CI O.886-0.981).Conclusions Calcaneal spur favored more females than males.Plantar spurs were more common than Achilles ones.Plantar spurs of Type B were more common than those of Type A.Achilles spurs were longer than plantar ones.More females suffered plantar spur than males.Right foot spurs were longer than left foot ones.Age had no significant influence on the spur characteristics.The incidence of spur might have been related to the Gissane angle,posterior facet inclination angle and height of the posterior facet of the foot.
9.A case-crossover study on the relationship between air pollution and acute onset of cerebral hemorrhage in Hangzhou city
Yu YE ; Xiu-Yang LI ; Kun CHEN ; Qing-Min LIU ; Hai-Qing XIANG
Chinese Journal of Epidemiology 2009;30(8):816-819
Objective To explore the relationship bet-ween air pollution and acute onset of cerebral hemorrhage in Hangzhou.Methods Time-stratified case-crossover study was used to analyze the effect of aerosol optical depth(AOD),PM10,SO2 and NO2 on the acute onset of cerebral hemorrhage.Conditional logistic regression was used to estimate the odds ratios(Ors) and their 95% confidence intervals(Cis) in relation to an increase of one unit of AOD and 10 μg/m3 of air pollutants.Results After adjusted temperature and relative humidity,the Ors of acute onset of cerebral hemorrhage by a unit increase in AOD at a 2 day-lag were 1.727(95%CI:1.103-2.703)in first half year and 2.412 (95%CI:1.230-4.733) at a 2 day-lag in spring.For a 10 μg/m3 increase in SO2,the Ors were 1.119(95% CI:1.019-1.229),1.230(95%CI:1.092-1.386),1.254(95%CI:1.076-1.460) in the whole year(2 day-lag),in first half year(2 day-lag) and in spring(2 day-lag),respectively.NO2 exposure in first half year(2 day-lag) was associated with cerebral hemorrhage,with OR as 0.841(95% CI:0.734-0.964).However,there were no statistical significances for AOD,SO2,NO2 in the rest time-periods(P>0.05).Additionally,no association was found between PM10 and the acute onset of cerebral hemorrhage in any time-periods(P>0.05).Conclusion Our data showed that there was association between air pollution and the acute onset of cerebral hemorrhage,especially in spring and in the first half of the year.
10.Role of bone marrow mesenchymal stem cells in the recovery of rat acute renal tubular damage
Xiang LIU ; Xue-Qing YU ; Jing NIE ; Zhi-Jian LI ; Xin AN ; Xiao-Yan LI ; Wen-Xing PENG ; Xiu-Qing DONG ;
Chinese Journal of Nephrology 2005;0(12):-
Objective To investigate whether mesenchymal stem cells can promote the recovery of acute renal tubular damage induced by mercuric chloride and to explore its possible mechanism.Methods Acute renal failure rat model was established by intraperitoneal injection of mercuric chloride.SD rats were randomly divided into three groups which were MSCs injection group, saline infusion group and normal control group.Seven days later,the changes of rat weight,survival,renal function and pathology were observed;PCNA,ED-1 and GFP were detected by immunohistochemistry; The expression of cytokines in kidney and the distribution of GFP plasmid-transfected MSCs in kidney were examined by RT-PCR.Results MSCs infusion ameliorated the decline of rat weight,survival, renal function,and pathological changes.PCNA and ED-1 positive cells in MSCs group were fewer than those in saline group.Expression of growth factors EGF,PDGF,HGF were obviously up- regulated and pre-inflammatory cytokines TNF-?was significantly reduced in MSCs-treated kidneys. GFP-labelled MSCs occurred occasionally in renal interstitium of MSCs-treated rats,but not in renal tubules.Conclusions Bone marrow mesenchymal stem cells can promote the recovery of acute renal tubular epithelial cells damage caused by mercuric chloride.The mechanism may partly depend on regulating the excretion of cytokines in renal microenvironment rather than completely depend on their differentiation to tubular cells.