1.Detection of HPV-DNA and SCCAg in the Follow-up of Cervical Squamous Cell Carcinoma Patients
Yu HUANG ; Qi ZHOU ; Dong WANG
Journal of Medical Research 2006;0(12):-
Objective To investigate the infection of human papilloma virus(HPV) and expression of serum squamous cell antigen (SCCAg) in the follow - up of 120 cervical squamous carcinoma patients who had received operation or operation combined with radiotherapy or only radiotherapy. Methods 120 cases of therapical cervical squamous carcinoma patients were detected HPV - DNA by HC - Ⅱ and serum SCCAg using immunohistochemical method. Results The positive rate of HPV - DNA and serum SCCAg was 49.17% and 17.50% , with a significant difference between them( P 0.05 ). Conclusion HPV - DNA test with HC - Ⅱ for follow - up of cervical squamous carcinoma patients was feasible. It was more sensitive than serum SCCAg. But it suggested that high risk type HPV -DNA test combined with serum SCCAg may be the independent prognostic factors.
2.QA and QC of Intravenous Injection in Radiology Department
Yan PENG ; Yueyong QI ; Yu ZHOU
Chinese Medical Equipment Journal 2003;0(10):-
Objective To investigate the quality assurance (QA) and quality control (QC)of intravenous injection in the radiology department. Methods The data from 1352 cases of intravenous injection in the radiology department were analyzed retrospectively. Results The bulge in region of the intravenous injection have been found in 28 cases, regional cyanochroia in 52 cases, allergic response in 25 cases, hypoglycemia response in 58 cases. Conclusion It is important to strengthen the QA and QC of intravenous injection in the radiology department.
3. Expression of galectin-3 in cervical cancer and its clinical significance
Tumor 2011;31(2):148-153
Objective: To evaluate the expression of galectin-3(Gal-3) in cervical cancer tissues and its correlation with clinicopathological and survival variables. Methods: One hundred and seventy-four patients with International Federation of Gynaecology and Obstetrics (FIGO) stage I/II cervical carcinoma undergoing radical surgery were selected, and their cervical cancer tissues were collected. The expression of Gal-3 protein in cancer tissues was semi-quantitatively tested by tissue microarray and immunohistochemical analysis. Then the correlations of the expression of Gal-3 with the clinicopathological parameters, treatment outcomes and the survival of these patients were evaluated. Results: The positive expression rate of Gal-3 was 54.0% (94/ 174) in the cervical cancer tissues. In a univariate analysis, the positive expression of Gal-3 was closely correlated with non-squamous cell carcinoma (P=0.006), lymph vascular-space invasion (LVSI, P=0.048), deep-muscle invasion ( P= 0.001) and pelvic lymph-node metastasis (P<0.001). The multivariate analysis revealed that the expression of Gal-3 was one of the independent risk factors for predicting pelvic lymph-node metastasis. The risk factors including FIGO stage II (P<0.001), LVSI ( P=0.013), positive parametrium invasion (P=0.015), pelvic lymph-node metastasis (P<0.001) and the positive expression of Gal-3 (P=0.013) were significantly correlated with poor overall survival in these patients with cervical cancer. The tumor remission rate was lower in patients with up-regulated expression of Gal-3 (39.7%) than that in patients with down-regulated or invariant expression of Gal-3 (70.0%) after receiving preoperative radiotherapy. Conclusion: Positive expression of Gal-3 protein is a predictive factor for pelvic lymph node metastasis and worse overall survival in patients with cervical cancer. Up-regulated expression of Gal-3 protein may be associated with the resistance to radiotherapy.
4.Non-optic nerve transecting evisceration combined with first stage hydroxyapatite orbital implantation
Yahlong BI ; Xiangsong HU ; Qi ZHOU ; Songyi WU ; Shifang YU
Chinese Journal of Medical Aesthetics and Cosmetology 2012;18(1):27-30
Objective To observe the clinical effects of a new method:non-optic nerve transecring evisceration combined with first stage hydroxyapatite orbital implantation.Methods One hundred and twenty two eyes (122 cases) were randomly divided into group A and group B,evisceration was first undertaken,the scleral wall was superior-temporally to inferior-nasally dissected and double scleral petals were placed before the implanted hydroxyapatite artificial eyeball.The difference between group A and group B was:in group A,the optic nerve was transected behind the eyeball,but in group B,a 2 mm outside the optic nerve scleral circle cutting was taken.Hemostasis time before implantation,tensile force during conjunctival suture,pain during surgery,palpebral fissure height after eye speculum wearing,operation time consuming,pain after surgery,conjunctival edema and congestion,and ocular prosthesis wearing time were compared between the two groups.Results In groups A and B,the intra-operative hemostasis time were (23.46 ± 6.96)mins and (5.49 ± 1.72)mins,the tensile force score during conjunctiva suture were 3.39±0.74 and 0.45±0.59,the score of pain in the first day were 2.8 ±0.68 and 1.47 ± 0.67,the ocular prosthesis wearing time after surgery were (6.27±2.73) and (3.07 ± 2.11)weeks,respectively.The differences of all the parameters above were with statistical significance between groups A and B (P<0.01).During 2 years follow-up,no complications such as orbital implant exposure or infection happened.Conclusions Compared to traditional methods,the non-optic nerve transecting evisceration method has merits of less impairment,short time-consuming,less pain,and quicker postoperative recovery.
5.The effects of pulmonary rehabilitation on the hospitalization rates and exercise endurance of patients with moderate or severe chronic obstructive pulmonary disease
Guihua CHEN ; Xiangdong ZHOU ; Lehua YU ; Yiqun LIU ; Qi LI
Chinese Journal of Physical Medicine and Rehabilitation 2012;34(6):444-447
Objective To investigate the effects of exercise therapy and health education on the hospitalization and exercise endurance of patients with moderate or severe chronic obstructive pulmonary disease (COPD).Methods A total of 86 patients with moderate or severe but stable COPD were divided randomly into an observation group (n=46) and a control group (n=40).The patients in both groups accepted general respiratory medical therapy.The patients in the observation group also accepted additional pulmonary rehabilitation therapy which consisted of exercise and health education while the patients in the control group only accepted health education and rehabilitation training guidance by telephone instead of standardized pulmonary rehabilitation therapy.The average recurrence of hospitalization,length of stay,and total bed time of all of the patients was tracked for a year before and after enrolment.Their 6 minute walking distance (6MWD) and quality of life (QOL) as reflected by using a scale recommended by the Chinese Society of Respiratory Disease before and after entering the study were evaluated.Results There was no significant difference between the groups in the year before entering the study in terms of their average frequency of hospitalization,length of stay or total bed time.In the year after enrollment average frequency of recurrence requiring hospitalization,length of stay and total bed time in the observation group all decreased significantly compared with the previous year,and all were significantly lower than in the control group.There were no significant differences between the groups in average 6MWD or average QOL score at entry,but in the subsequent year both groups' results improved significantly.Conclusion Long term pulmonary rehabilitation can not only enhance exercise endurance,it also improves QOL and relieves the economic burden of COPD patients on society.
6.Effect of Anti-polluted Mattress Protecting Covering
Suqin TANG ; Fenglian ZHOU ; Linna WANG ; Qi YU ; Hong XIAO
Chinese Journal of Nosocomiology 1994;0(01):-
OBJECTIVE To discuss the available methods of preventing the mattress pollution in the wards of the(hospital), and to keep the mattresses clean and dry and eliminate the hidden danger of nosocomial infection.(METHODS) The mattress protective covering is used of a new type of textile materials,and then applied into clinic.Selected 100 pieces of mattresses in the wards,divided them equally into two groups at random,the(experimental) group and the control group.After cleaning and pasteurization(surface) sampling and bacterial culturing for every mattress were undertaken.For the experimental group,spread the protective(covering) before the sheet,and for the control group,used the sheet directly.The colony number of each group was compared in the 3rd,7th,and 14th days.RESULTS The mattresses of experimental group were clean,light polluted and with less colonies,and that of the control group were heavy polluted and with more colonies.The comparisons of the total colony number and the number of every sampling point in the 3rd,7th,and 14th days of the two groups showed that there was a(significant) difference(P
7.Comparison of dexamethasone and granisetron for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy
Xiangmei BU ; Xiaoliang QI ; Zhou WANG ; Wenbin YU
Chinese Journal of Current Advances in General Surgery 1999;0(04):-
Objective:To compare dexamethasone and granisetron for the prevention of PONV(Postoperative nausea and vomiting) after LC(Laparoscopic cholecystemy).Methods:A total of 80 patients were randomly divided into four groups(n= 20 each).A:dexamethasone 8 mg group;B:granisetron 3 mg,C:combined application group,D were the control group.All patients were given the similiar standardized anesthesia and operative treatment.PONV were assessed during the first 24 h after operations.Results:Group A,B and C got higher scores of PONV than the control group(P
8.Tissue Equalization Technique Applied in DR Thoracolumbar Vertebral Body Photography
Yu ZHOU ; Yueyong QI ; Kaiyu JING ; Daoyou XI
Chinese Medical Equipment Journal 2003;0(10):-
Objective To assess the examinational value of tissue equalization (TE)technique in DR thoracolumbar vertebral body photography. Methods 48 cases were reformed using the conventional DR method in the thoracolumbar vertebral body photography,compared with the TE technique in DR thoracolumbar vertebral body photography. Results The details in different thickness area of body could be revealed clearly in the same image produced by TE technique. The visualization of image details could be obviously improved by using the TE technique. Conclusion It is important to apply the TE technique in DR thoracolumbar vertebral body photography.
9.Construction and application of picture archiving and communication system based on digital teaching platform of medical imaging
Liguang ZOU ; Dong ZHANG ; Yueyong QI ; Yu ZHOU ; Qichuan ZHANG
Chinese Journal of Medical Education Research 2012;11(1):53-56
Picture archiving and communication system ( PACS ) based on digital teaching platform of medical imaging consists of web teaching system and teaching resource library of medical imaging.The web teaching system includes four function modules of classroom management,work management,teaching management and test management.The teaching resource library includes script,pictures,and audio,video and animation materials of theoretical books,typical cases,examination techniques and medical imaging equipments.Utilized in theoretical and practical classes,the teaching characteristic of medical imaging is made prominent,and the subjective motility of the students is brought into play.