The fibre projections of the caudate nucleus to the cerebral cortex and the nonspecific thalamic nucleus in the rabbit were studied by tracing the degenerated axons and terminal fibres from electrolytic lesions in the head portion of the nucleus on sections prepared with Nauta and Glees methods.The results were as follows:The efferent fibres from the head portion of the caudate nucleus were projected to frontal (especially the praecentral areas) and limbic cortex, and terminated in all the layers of the cerebral cortex.The efferent fibres from the head portion of the caudate nucleus were projectet to the centromedian nucleus and parafascicular nucleus of the nonspecific thalamic nuclei.The above observations suggest that the projection of the efferent fibres from the caudate nucleus to the cerebral cortex and nonspecific thalamic nuclei may be a parf of the nonspecific conducting pathway; and the caudate nucleus is not only a part do the extrapyramidal system but a structure of the nonspecific conducting system which may serve as the morphological basis for the role played by the caudate nucleus in the acupunctural analgesia.

Objective To explore the efficacy of captopril and methylprednisolone in the implosive therapy of RNS.Methods 21 cases of RNS who have captopril 1.25 mg/d and intravenous dripping methylprednisolone of 20mg/kg·d sustained 1-2h for 3 days,if non-remissions,using once more after a week.Results 21 cases of children with complete remission in 13 cases,partial remission in 5 cases,non-remission in 3 cases.The overall response rate was 86%.In complete remission 13 cases,4 cases remission after 2 courses treatment,5 cases remission after four courses treatment,4 cases remission after 6 courses treatment.Conclusion Combined captopril with methylprednisolone in treating refractory nephritic syndrome can improve the rate of remission.

? Diabetic retinopathy is one of those significant complications of diabetes.With the increasing number of diabetic patients, blind caused by diabetic retinopathy is a serious threat to human health which cannot be neglected, but there is no highly effective treatment for it. Consequently, early detection and preventive treatment for it are important.Currently, studies have found that urine microalbumin had a close relation with diabetic retinopathy and that urine microalbumin might play an important role in early predicting of diabetic retinopathy. The review is about the diagnostic significance of urine microalbumin test for early diabetic retinopathy.

Objective To evaluate the effect of bandage rollers compression on pocket hemostasis in patients after implantation of permanent pacemaker.Methods A total of 591 patients after implantation of permanent pacemaker were enrolled in this study and divided into trial group and control group.The wounds of 296 patients in trial group received compression by two bandage rollers,which were placed parallelly on the wound side by side,above the pocket of pacemaker,fixed by 3M adhesive tapes so that no bleeding of wound and no shifting of rollers.6 hours after the operation,the tapes and bandage rollers were released.The wounds of 295 patients in control group received compression by 1 000 g sand bag which were taken off 6 hours after the operation.The safety and effects of hemostasis in patients between the two groups were compared.Results The incidences of incision bleeding,pocket hematoma and pocket skin pressure injury were not significantly different between the two groups(P>0.05).The incidences of postoperative pain,urinary retention and insomnia were significantly different between the two groups(P<0.05).Conclusion The incidences of postoperative pain,urinary retention and insomnia are significantly reduced in patients who received bandage roller compression.

Glycosylated hemoglobin A1c(HbA1c)is the products of slow,continuous non-enzymatic saccharification reaction,which can reflect the average blood glucose of 2~3 months of the patients,and it is the most important index for long-term monitoring of glucose.There are so many methods for detecting HbA1c that America,Japan and Swede proposed their own standardized detection methods to reduce the difference laboratories.However,these methods were non-specific.A new method for was developed by International Federation of Clinical Chemistry and laboratory medicine (IFCC) in 2007,which was of high specificity,but which resulted in relatively low glycosylated hemoglobin.To avoid the confusion in reference value of glycosylated hemoglobin,average blood glucose was recommended by American Diabetes Association (ADA),European Association for the Study of Diabetes (EASD),and International Diabetes Federation (IDF).This paper review the origin of average blood glucose substituting HbA1c,relationship of HbA1c with average blood glucose,and the international multiple-center research of ADAG and its enlightenment,and we also discuss the relevant development in future.

Objective To study effect of triple viable bacterium of bacillus (small peifeikang) on the intestinal microflora and inflammation factors in patients with infectious diarrhea.Methods From October 2010 to October 2014, 120 patients with infectious diarrhea were chosen as study objects, 30 cases of health examination were selected as healthy control group, All patients were divided into 2 groups:60 patients in small peifeikang group and 60 patients in control group.The therapeutic effect and the change of intestinal microflora and inflammation factors were compared between two groups.Results The effective rate of small peifeikang groupwas 100.00%, while that of control group was 96.67%,the difference had statistical significance (χ2 =5.52,P<0.05).The symptom disappearance time of diarrhea, vomiting and fever had statistical difference between two groups (P<0.05), that of dehydration had no statistical significance.After treatment, in small peifeikang group and control group, the number of bifidobacterium, lactobacillus, and B/E value had decreased significantly (P<0.05), and the number of intestinal bacteriahad increased significantly(P<0.05).The distribution of intestinal flora in small peifeikang group was better than that of control group, and the difference had statistical significance(P<0.05).After treatment, in small peifeikang group and control group, the level of endotoxin, IL -6, TNF-αand CRP had decreased significantly( P <0.05).The extent of decreasing in small peifeikang group was more significant than that of control group, and the difference had statistical significance ( P <0.05 ) . Conclusion The triple viable bacterium of bacillus can promote the recurrence of patients with infectious diarrhea by adjusting the distribution of intestinal microflora, and by its immune regulation function.

OBJECTIVE: To investigate the effect of aerobic exercise on immune factor IL-4, TNF-alpha in patients with allergic rhinitis, which provide a theoretical basis for the treatment of allergic rhinitis. METHOD: Thirty-two allergic rhinitis patients were selected and divided into a control group (14 people) and the experimental group (18 people). During the treatment, both groups receive conventional symptomatic treatment. Meanwhile, aerobic exercise therapy is applied to the experimental group for 40 - 60 minutes a day, 3 - 4 days a week. Serum IL-4, TNF-alpha and allergic rhinitis symptoms graded scoring were tested before and after 6 month therapy. RESULT: After six months of exercise intervention, the 11-4, and TNF-alpha levels of experimental group were significantly lower than the level of control group. The symptoms score is also significantly decreased in experimental group. CONCLUSION Aerobic exercise had good therapeutic effect in patients with allergic rhinitis. The mechanism may be that aerobic exercise can reduce the level of IL-4 and TNF-alpha, which can relieve infiltration and activation of inflammatory cells.
Adolescent ; Adult ; Exercise ; Exercise Therapy ; Female ; Humans ; Interleukin-4 ; blood ; Male ; Rhinitis, Allergic ; Rhinitis, Allergic, Perennial ; blood ; therapy ; Tumor Necrosis Factor-alpha ; blood ; Young Adult

Objective To explore the neuroprotective effect of magnesium sulfate on radiation induced neural stem cell injury. Methods Brain tissue was obtained from new-born sprague-dawley rats within 24 hours, and the cerebral hemisphere was dissociated to culture the neural stem cells. After being identified by immunofluorescence method, the neural stem cells were randomly divided into 3 groups as blank control group, experimental control group and experimental group. The neural stem cells of experimental control group and experimental group were irradiated with 2 or 4 Gy of gamma rays. The proliferation and the cell cycle of neural stem cells were detected at different time-points ranging from 24 h,48 h, 72 h after irradiation with CCK-8 and FCM. Results Compared with the blank control group, the proliferation rate of experimental control group was significantly reduced ( t = 5. 33-8.44, P ＜ 0. 05 ), and the G1 phase arrest of experimental control group was significantly enhanced ( t = 30. 60-71.22, P ＜ 0. 05 ).Compared with the experimental control group, the proliferation of experimental group significantly increased excluding that of 24 h ( t = 2.45-4. 71, P ＜ 0.05 ), the apoptosis rate of experimental group significantly decreasd (t = 6.73-41.12, P ＜ 0.05 ), which was closer to the blank control group.Conclusion Magnesium sulfate can alleviate the injury of proliferation and decrease the cell apoptosis in the early stage after irradiation.

Objective To develop a multi-parametric objective evaluation protocol and investigate its correlation with perceptual analysis of continuous speech for objectivity and quantitatively. Methods The voice samples were collected from 135 patients with dysphonia and 29 subjects with normal voice. The objective parameters, including fundamental frequency (F 0), intensity, jitter, signal-to-noise ratio, Lyapunov coefficient (LC),oral airflow (OAF), vocal range (Range) and maximum phonatory time (MPT) which were measured mainly on a sustained /a/ and estimated subglottic pressure (ESGP) which was determined on a series of /pa/,were recorded on an "EVA" workstation which was developed in French. According to the G (overall dysphonia) component of the GRBAS score on a 4-point scale ranging from 0 for normal to 3 for severe dysphonia, the perceptual analysis was done by a jury composed of 4 experienced listeners and the voice samples (continuous speech) were from the same patients with normal voices and normal intensity. Results Using the discriminate analysis, a seven parameters protocol (Range, LC, ESGP, MPT, OAF, signal-to-noise ratio and F 0) was developed. Result showed that this protocol allowed 84% concordance with jury classification.Conclusion The objective voice evaluation is multi-parametric and is able to reflet the result of perceptual analysis.

The measures taken by Library of Southern Medical University to improve the use of its electronic re-sources were described according to the major problems in use of electronic resources in domestic college and uni-versity libraries from resources assessment, resources integration and revealing, resources popularization and librarians support, with certain rational suggestions proposed for increasing the utilization ratio of electronic resources, inclu-ding popularization of resources, training of user information literacy, and improvement of users ability.